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The map label for this gene is pkn1 [H]

Identifier: 82702016

GI number: 82702016

Start: 1008576

End: 1009298

Strand: Reverse

Name: pkn1 [H]

Synonym: Nmul_A0887

Alternate gene names: 82702016

Gene position: 1009298-1008576 (Counterclockwise)

Preceding gene: 82702018

Following gene: 82702014

Centisome position: 31.7

GC content: 54.91

Gene sequence:

>723_bases
ATGCAACTCATGAAATTGGTATATCTTCGCCCCCTGCACACCTCAGCTTTAGCGCTATTCATAAGCATTGTCGCGCTCTT
TTGCAATCCGGTGACGGCGAGCGAAAACAATACCTTGAACTCCGCAAAAGCGTGCCCCGTCTGTCCTGAAATGGTATCCA
TTGCAGGCAAGAAATTTGCCATGGGTAAATACGCCGTAACGTTCGACGACTGGGAGGCGTGTGTTGAAGGAGGCGGCTGC
GGTGGGTATGTTCCCCCCGATAATGGCTGGGGGCGCGGTAAAAGACCGGTTGTGAATGTAAGCTGGGATGACGCGCAAGC
TTACTTGCGATGGCTGTCGGATAAGTCCGGCAAGACTTACCGGCTGCCCACGGAAGAGGAATGGGAAGTTGCCACCCTGG
CCGGCGCGACTACTCAATACTATTGGGGCAACGACGTCGGGCGCAATAACGCCAATTGCGATGGATGCGGGAGCGAGTGG
GATAACAGGAGAACCGCTCCTGTCGGCAGTTTCAAACCTAATGCCTTTGGCCTGTACGATATGATGGGGAATGTCTGGCA
GTGGATGGATACCTGCCGGAAAGGGAATTGTGCAAAACGCCTCCTGTGCGGTGGCTCCTGGAATCACCGGCCCCAGGACA
TGCGGGCGGGTATGTGCAACTGGTTCGATACCAACAAACGTATGCGCTATCTGGGTTTTCGACCTGCAATGACGGTGCCC
TGA

Upstream 100 bases:

>100_bases
CATATTGCCTGCATTAATCTGATTCTTCGTGAAGTTTTGGATATCAACGGCTTTTCTATACAATTATCGAATTTGCTGGC
CAGTCTTTTCACTTGCTCAG

Downstream 100 bases:

>100_bases
AGCACACCTGCTCTTTTTTTCCCCTTTCCCCCAATTTTTTATTCTCCCCCGACCTCTCTTCCGCAAGTGAGAGAGGGGAG
TGAGGACCTCGGCCGGATTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MQLMKLVYLRPLHTSALALFISIVALFCNPVTASENNTLNSAKACPVCPEMVSIAGKKFAMGKYAVTFDDWEACVEGGGC
GGYVPPDNGWGRGKRPVVNVSWDDAQAYLRWLSDKSGKTYRLPTEEEWEVATLAGATTQYYWGNDVGRNNANCDGCGSEW
DNRRTAPVGSFKPNAFGLYDMMGNVWQWMDTCRKGNCAKRLLCGGSWNHRPQDMRAGMCNWFDTNKRMRYLGFRPAMTVP

Sequences:

>Translated_240_residues
MQLMKLVYLRPLHTSALALFISIVALFCNPVTASENNTLNSAKACPVCPEMVSIAGKKFAMGKYAVTFDDWEACVEGGGC
GGYVPPDNGWGRGKRPVVNVSWDDAQAYLRWLSDKSGKTYRLPTEEEWEVATLAGATTQYYWGNDVGRNNANCDGCGSEW
DNRRTAPVGSFKPNAFGLYDMMGNVWQWMDTCRKGNCAKRLLCGGSWNHRPQDMRAGMCNWFDTNKRMRYLGFRPAMTVP
>Mature_240_residues
MQLMKLVYLRPLHTSALALFISIVALFCNPVTASENNTLNSAKACPVCPEMVSIAGKKFAMGKYAVTFDDWEACVEGGGC
GGYVPPDNGWGRGKRPVVNVSWDDAQAYLRWLSDKSGKTYRLPTEEEWEVATLAGATTQYYWGNDVGRNNANCDGCGSEW
DNRRTAPVGSFKPNAFGLYDMMGNVWQWMDTCRKGNCAKRLLCGGSWNHRPQDMRAGMCNWFDTNKRMRYLGFRPAMTVP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=125, Percent_Identity=39.2, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI194248088, Length=125, Percent_Identity=39.2, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI226437577, Length=125, Percent_Identity=39.2, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI257470977, Length=108, Percent_Identity=39.8148148148148, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI38202250, Length=108, Percent_Identity=39.8148148148148, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI257470975, Length=108, Percent_Identity=39.8148148148148, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20130397, Length=129, Percent_Identity=35.6589147286822, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 26817; Mature: 26817

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
9.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLMKLVYLRPLHTSALALFISIVALFCNPVTASENNTLNSAKACPVCPEMVSIAGKKFA
CCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEE
MGKYAVTFDDWEACVEGGGCGGYVPPDNGWGRGKRPVVNVSWDDAQAYLRWLSDKSGKTY
CCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEE
RLPTEEEWEVATLAGATTQYYWGNDVGRNNANCDGCGSEWDNRRTAPVGSFKPNAFGLYD
ECCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
MMGNVWQWMDTCRKGNCAKRLLCGGSWNHRPQDMRAGMCNWFDTNKRMRYLGFRPAMTVP
HHHHHHHHHHHHCCCCHHHHHEECCCCCCCCHHHHCCCCCEECCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MQLMKLVYLRPLHTSALALFISIVALFCNPVTASENNTLNSAKACPVCPEMVSIAGKKFA
CCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEE
MGKYAVTFDDWEACVEGGGCGGYVPPDNGWGRGKRPVVNVSWDDAQAYLRWLSDKSGKTY
CCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEE
RLPTEEEWEVATLAGATTQYYWGNDVGRNNANCDGCGSEWDNRRTAPVGSFKPNAFGLYD
ECCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
MMGNVWQWMDTCRKGNCAKRLLCGGSWNHRPQDMRAGMCNWFDTNKRMRYLGFRPAMTVP
HHHHHHHHHHHHCCCCHHHHHEECCCCCCCCHHHHCCCCCEECCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]