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The map label for this gene is holC [H]

Identifier: 82701878

GI number: 82701878

Start: 868688

End: 869110

Strand: Reverse

Name: holC [H]

Synonym: Nmul_A0745

Alternate gene names: 82701878

Gene position: 869110-868688 (Counterclockwise)

Preceding gene: 82701879

Following gene: 82701877

Centisome position: 27.29

GC content: 54.61

Gene sequence:

>423_bases
ATGACGGAAATCGACTTCTACTCGGGCGGGGGAGACCGGCTCCATACCGCCTGTCGTCTGGTTGCAACAGCCGTGCGGAA
AGGATTCAAGGTCATGATTTACGCGCCTGACATGGCTACGGTCGAGCAGATCGATAAGTTGTTGTGGACTTTCTCTGCGA
CCGATTTTATTCCGCACTGCCAGACAGACGACAAGCTGGCTGAGTTCACGCCGGTAACACTCAGCGATAGTGGAAGGAAT
CCGCCGCACGATGATGTATTGCTCAACCTGGGCCCTGAAAACCCTCCTTTCTTCAGCCGCTTCCGGCGACTCATTGAAAT
TGCGGGCAACACGGACGAAGATACCCAGGCCGCAAGGAAACGCTACCGGTTTTATCAGGATCGTGGTTACGAAATACGGC
ATCACCGCCTTGGTGCCGTATAG

Upstream 100 bases:

>100_bases
CGGTACCGCTGCTCACCCAGTTTTTGATCAGCCGGACTACCAGACAACCCGGTAGCACTGGCGAGACCGGCAGCCGCAAG
AACCGGCGCAAATCGAAGGA

Downstream 100 bases:

>100_bases
GCAGACAGACACCAAATCATGCCAAATCGCGCAGCAGGTATCAATTCCCGGAGTTCCGCCCCCTCTCTTTATCAACCGGC
ATTTCAATGACAAACAGCAA

Product: DNA polymerase III chi subunit, HolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTEIDFYSGGGDRLHTACRLVATAVRKGFKVMIYAPDMATVEQIDKLLWTFSATDFIPHCQTDDKLAEFTPVTLSDSGRN
PPHDDVLLNLGPENPPFFSRFRRLIEIAGNTDEDTQAARKRYRFYQDRGYEIRHHRLGAV

Sequences:

>Translated_140_residues
MTEIDFYSGGGDRLHTACRLVATAVRKGFKVMIYAPDMATVEQIDKLLWTFSATDFIPHCQTDDKLAEFTPVTLSDSGRN
PPHDDVLLNLGPENPPFFSRFRRLIEIAGNTDEDTQAARKRYRFYQDRGYEIRHHRLGAV
>Mature_139_residues
TEIDFYSGGGDRLHTACRLVATAVRKGFKVMIYAPDMATVEQIDKLLWTFSATDFIPHCQTDDKLAEFTPVTLSDSGRNP
PHDDVLLNLGPENPPFFSRFRRLIEIAGNTDEDTQAARKRYRFYQDRGYEIRHHRLGAV

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 16021; Mature: 15890

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIDFYSGGGDRLHTACRLVATAVRKGFKVMIYAPDMATVEQIDKLLWTFSATDFIPHC
CCCCCEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCC
QTDDKLAEFTPVTLSDSGRNPPHDDVLLNLGPENPPFFSRFRRLIEIAGNTDEDTQAARK
CCCCCHHHCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
RYRFYQDRGYEIRHHRLGAV
HHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure 
TEIDFYSGGGDRLHTACRLVATAVRKGFKVMIYAPDMATVEQIDKLLWTFSATDFIPHC
CCCCEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCC
QTDDKLAEFTPVTLSDSGRNPPHDDVLLNLGPENPPFFSRFRRLIEIAGNTDEDTQAARK
CCCCCHHHCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
RYRFYQDRGYEIRHHRLGAV
HHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9864319; 10984043 [H]