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The map label for this gene is iscR [H]

Identifier: 82701827

GI number: 82701827

Start: 801292

End: 801810

Strand: Direct

Name: iscR [H]

Synonym: Nmul_A0694

Alternate gene names: 82701827

Gene position: 801292-801810 (Clockwise)

Preceding gene: 82701826

Following gene: 82701828

Centisome position: 25.16

GC content: 53.37

Gene sequence:

>519_bases
ATGAGGCTAACAACCAAAGGACGGTTTGCAGTAACGGCGTTGCTTGATCTTGCGCTGCAACGCCAGACGCGTCCTGTGAC
ACTTGCGGAAATCAGTCAGCGCCAGCAGATTTCGCTATCTTATCTTGAGCAATTGTTCGCCAAACTGCGTTCCCGAGGAC
TCGTCGATAGTGTAAGAGGCCCGGGTGGCGGCTATTGCCTTGCGAAAGACATGGGGCAAGTGTCGGTTGCCGAGATCATT
CTCGCGGTTGACGAACCTATCGATTCAACTCAGTGCAATGGAAAGGAGAATTGCCACAACGACAGGAAATGCATGACGCA
TGACTTGTGGACAAAGCTCAACGAACTGATTTTCGACCACCTCGGCGCAGTTACGCTGAAACAACTGGTCGATGAGCAGA
GGGAAAGAGAGGAAAGGCGGAAGGCAAGAGAGGCAGGGGTGGTGCAGATGCTGGATATGCGGAAGGCTGGGTCTGAAAAG
GTCATACCCGATCGGAGCCGCACTGCAGTTTCTGCCTGA

Upstream 100 bases:

>100_bases
GTTGACTAAATCAGTCATCTATTGAACTTCTGCTGACTGAGATATTTCTGAACCTATCTACTTAATCCGTGAAGCCATCG
AGAGCAAAGAGGAGTTCATC

Downstream 100 bases:

>100_bases
CTTCAATTCTGAATGCCGAACGCTTACTTTCGTTGTCATAATCGCATGATGGTAGACGGAGAATGGCGATGTCAATAACA
CTGACTGAAAACGCGGCAAA

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRLTTKGRFAVTALLDLALQRQTRPVTLAEISQRQQISLSYLEQLFAKLRSRGLVDSVRGPGGGYCLAKDMGQVSVAEII
LAVDEPIDSTQCNGKENCHNDRKCMTHDLWTKLNELIFDHLGAVTLKQLVDEQREREERRKAREAGVVQMLDMRKAGSEK
VIPDRSRTAVSA

Sequences:

>Translated_172_residues
MRLTTKGRFAVTALLDLALQRQTRPVTLAEISQRQQISLSYLEQLFAKLRSRGLVDSVRGPGGGYCLAKDMGQVSVAEII
LAVDEPIDSTQCNGKENCHNDRKCMTHDLWTKLNELIFDHLGAVTLKQLVDEQREREERRKAREAGVVQMLDMRKAGSEK
VIPDRSRTAVSA
>Mature_172_residues
MRLTTKGRFAVTALLDLALQRQTRPVTLAEISQRQQISLSYLEQLFAKLRSRGLVDSVRGPGGGYCLAKDMGQVSVAEII
LAVDEPIDSTQCNGKENCHNDRKCMTHDLWTKLNELIFDHLGAVTLKQLVDEQREREERRKAREAGVVQMLDMRKAGSEK
VIPDRSRTAVSA

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=133, Percent_Identity=57.1428571428571, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 19308; Mature: 19308

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTALLDLALQRQTRPVTLAEISQRQQISLSYLEQLFAKLRSRGLVDSVRG
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
PGGGYCLAKDMGQVSVAEIILAVDEPIDSTQCNGKENCHNDRKCMTHDLWTKLNELIFDH
CCCCEEHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGAVTLKQLVDEQREREERRKAREAGVVQMLDMRKAGSEKVIPDRSRTAVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLTTKGRFAVTALLDLALQRQTRPVTLAEISQRQQISLSYLEQLFAKLRSRGLVDSVRG
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
PGGGYCLAKDMGQVSVAEIILAVDEPIDSTQCNGKENCHNDRKCMTHDLWTKLNELIFDH
CCCCEEHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGAVTLKQLVDEQREREERRKAREAGVVQMLDMRKAGSEKVIPDRSRTAVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]