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The map label for this gene is fabZ

Identifier: 82701800

GI number: 82701800

Start: 763662

End: 764102

Strand: Direct

Name: fabZ

Synonym: Nmul_A0667

Alternate gene names: 82701800

Gene position: 763662-764102 (Clockwise)

Preceding gene: 82701799

Following gene: 82701801

Centisome position: 23.98

GC content: 53.74

Gene sequence:

>441_bases
ATGGATATCCATGAAATTCTGAAATACCTTCCTCACCGTTACCCCTTGCTCCTCGTCGATCGCGTTCTCGCTTTCGAACC
GGGAAAGAGCCTCACCGCGCTCAAGAACGTAACGATCAACGAACCTTTTTTTACGGGACACTTTCCTCATCATCCCGTCA
TGCCCGGGGTATTGGTGATCGAAGCGCTGGCGCAGGCTGCCGCTCTTCTGACGCTCAAAACATCCAATGTGGAAGCCGAC
GAGAATTCCATCTATTATTTCGTTGGCATCGATAATGCGCGTTTCAAGCGGCCGGTGGAACCGGGCGATCAACTGATACT
CAAGGCTACAGTTCTGAAGGAGAGGATCGGAATCTGGAAATATGCGGCACGGGCGGAAGTGGACGGCCGCGTTGCCGCCG
AGGCCGAACTGATGTGTACCGTCAGGCCAAAAGAGACCTGA

Upstream 100 bases:

>100_bases
GTCAGGGACAACGGGCAAGTCCGTCTCTCCTCCGATCATCTCAATCCTCTGATCATCCTTTATCCACTTCTTATCAAGAA
CCCGGGAAAACATCGCGCTA

Downstream 100 bases:

>100_bases
AATACCTGCGGAAAAACGGCAGAGTTGATCCATGTGCAGCAATGAATATCCTTGGGTCTGCGGTGTGGATGAGGCCGGCC
GGGGGCCGCTGGCAGGACCG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MDIHEILKYLPHRYPLLLVDRVLAFEPGKSLTALKNVTINEPFFTGHFPHHPVMPGVLVIEALAQAAALLTLKTSNVEAD
ENSIYYFVGIDNARFKRPVEPGDQLILKATVLKERIGIWKYAARAEVDGRVAAEAELMCTVRPKET

Sequences:

>Translated_146_residues
MDIHEILKYLPHRYPLLLVDRVLAFEPGKSLTALKNVTINEPFFTGHFPHHPVMPGVLVIEALAQAAALLTLKTSNVEAD
ENSIYYFVGIDNARFKRPVEPGDQLILKATVLKERIGIWKYAARAEVDGRVAAEAELMCTVRPKET
>Mature_146_residues
MDIHEILKYLPHRYPLLLVDRVLAFEPGKSLTALKNVTINEPFFTGHFPHHPVMPGVLVIEALAQAAALLTLKTSNVEAD
ENSIYYFVGIDNARFKRPVEPGDQLILKATVLKERIGIWKYAARAEVDGRVAAEAELMCTVRPKET

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=54.6762589928058, Blast_Score=166, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_NITMU (Q2YB97)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411366.1
- ProteinModelPortal:   Q2YB97
- SMR:   Q2YB97
- STRING:   Q2YB97
- GeneID:   3785152
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0667
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q2YB97
- ProtClustDB:   PRK00006
- BioCyc:   NMUL323848:NMUL_A0667-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16364; Mature: 16364

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: ACT_SITE 47-47

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIHEILKYLPHRYPLLLVDRVLAFEPGKSLTALKNVTINEPFFTGHFPHHPVMPGVLVI
CCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEHEECCCCCCCEEECCCCCCCCCCHHHHH
EALAQAAALLTLKTSNVEADENSIYYFVGIDNARFKRPVEPGDQLILKATVLKERIGIWK
HHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCHHEEHHHHHHHHHHHHHH
YAARAEVDGRVAAEAELMCTVRPKET
HHHHCCCCCCEECCEEEEEEECCCCC
>Mature Secondary Structure
MDIHEILKYLPHRYPLLLVDRVLAFEPGKSLTALKNVTINEPFFTGHFPHHPVMPGVLVI
CCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEHEECCCCCCCEEECCCCCCCCCCHHHHH
EALAQAAALLTLKTSNVEADENSIYYFVGIDNARFKRPVEPGDQLILKATVLKERIGIWK
HHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCHHEEHHHHHHHHHHHHHH
YAARAEVDGRVAAEAELMCTVRPKET
HHHHCCCCCCEECCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA