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The map label for this gene is aroK

Identifier: 82701785

GI number: 82701785

Start: 749996

End: 750583

Strand: Reverse

Name: aroK

Synonym: Nmul_A0652

Alternate gene names: 82701785

Gene position: 750583-749996 (Counterclockwise)

Preceding gene: 82701787

Following gene: 82701777

Centisome position: 23.57

GC content: 55.95

Gene sequence:

>588_bases
ATGATTTCAACAGATGCAGTTGCTCCCGCAGTTGATGTGAAAGGGGAGGCTGGCGATCGCGCAGCCACCGGAAACATCTT
TCTGGTCGGGATGATGGGGGCCGGAAAAACGACGGTGGGCAGGCTCCTCTCCCATTTTCTGGAAAAAACCTTTTACGATT
CGGATCGGGAAATACAGAAACGAACGGGTGTCAGTATTCCCACGATCTTCGAGATCGAAGGAGAAGAAGGCTTTCGCAGG
CGCGAAACCGAGATACTGTCCGAACTCATGAATGCAAGGAATATCATTCTGGCAACGGGAGGCGGAGCCGTATTGAGTGG
AGTAAACCGGGCAATGCTGAAGCACGGCGGCACGGTGATATATCTGCGAGCGTCCATCGACGACCTGTGGCGCCGCACCC
GGCATGACAAGAACCGTCCGCTGCTGCAAACTTCCGACCCGCGCGCACGACTGGCTGAACTGTTTGTGCAGCGTGACCCC
TTATATCGGGAGACGGCCCATATCGTAGTTGAGAGCGGGAAGCGAAGCCCCCGGCATCTGGCTCAATCACTGGCACAGCA
ACTGACGATCTCATCCCGCACCGGATAA

Upstream 100 bases:

>100_bases
GTAGCGGCCTTTTGATATTCCTGTGAAGAATCGGCCGGAGTACTGAAAACTCGGGTAGTGGAATAGGTGCAATACTTATA
TTTCCGCTACAATTCTCCCA

Downstream 100 bases:

>100_bases
AATAAGAACCGTAGGAAGTTCTGTTCGTTTCCCTTTCCGTCGTTTGGAAAACTGCTACTCGGCCAAGGGTGGTCTGTCCG
GGAACAGCACATCGGTAAAA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MISTDAVAPAVDVKGEAGDRAATGNIFLVGMMGAGKTTVGRLLSHFLEKTFYDSDREIQKRTGVSIPTIFEIEGEEGFRR
RETEILSELMNARNIILATGGGAVLSGVNRAMLKHGGTVIYLRASIDDLWRRTRHDKNRPLLQTSDPRARLAELFVQRDP
LYRETAHIVVESGKRSPRHLAQSLAQQLTISSRTG

Sequences:

>Translated_195_residues
MISTDAVAPAVDVKGEAGDRAATGNIFLVGMMGAGKTTVGRLLSHFLEKTFYDSDREIQKRTGVSIPTIFEIEGEEGFRR
RETEILSELMNARNIILATGGGAVLSGVNRAMLKHGGTVIYLRASIDDLWRRTRHDKNRPLLQTSDPRARLAELFVQRDP
LYRETAHIVVESGKRSPRHLAQSLAQQLTISSRTG
>Mature_195_residues
MISTDAVAPAVDVKGEAGDRAATGNIFLVGMMGAGKTTVGRLLSHFLEKTFYDSDREIQKRTGVSIPTIFEIEGEEGFRR
RETEILSELMNARNIILATGGGAVLSGVNRAMLKHGGTVIYLRASIDDLWRRTRHDKNRPLLQTSDPRARLAELFVQRDP
LYRETAHIVVESGKRSPRHLAQSLAQQLTISSRTG

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=46.0606060606061, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1786587, Length=174, Percent_Identity=34.4827586206897, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_NITMU (Q2YBB2)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411351.1
- ProteinModelPortal:   Q2YBB2
- SMR:   Q2YBB2
- STRING:   Q2YBB2
- GeneID:   3785137
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0652
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- PhylomeDB:   Q2YBB2
- BioCyc:   NMUL323848:NMUL_A0652-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 21542; Mature: 21542

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 55-55 BINDING 79-79 BINDING 101-101 BINDING 139-139 BINDING 158-158 BINDING 175-175

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTDAVAPAVDVKGEAGDRAATGNIFLVGMMGAGKTTVGRLLSHFLEKTFYDSDREIQK
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RTGVSIPTIFEIEGEEGFRRRETEILSELMNARNIILATGGGAVLSGVNRAMLKHGGTVI
HCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
YLRASIDDLWRRTRHDKNRPLLQTSDPRARLAELFVQRDPLYRETAHIVVESGKRSPRHL
EEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHEECCCCCHHHH
AQSLAQQLTISSRTG
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MISTDAVAPAVDVKGEAGDRAATGNIFLVGMMGAGKTTVGRLLSHFLEKTFYDSDREIQK
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RTGVSIPTIFEIEGEEGFRRRETEILSELMNARNIILATGGGAVLSGVNRAMLKHGGTVI
HCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
YLRASIDDLWRRTRHDKNRPLLQTSDPRARLAELFVQRDPLYRETAHIVVESGKRSPRHL
EEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHEECCCCCHHHH
AQSLAQQLTISSRTG
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA