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The map label for this gene is nadA [H]

Identifier: 82701738

GI number: 82701738

Start: 686851

End: 687951

Strand: Direct

Name: nadA [H]

Synonym: Nmul_A0605

Alternate gene names: 82701738

Gene position: 686851-687951 (Clockwise)

Preceding gene: 82701737

Following gene: 82701739

Centisome position: 21.57

GC content: 55.59

Gene sequence:

>1101_bases
ATGCAAGCGGAAGCCATTGCCTTTGAACGTTTCGATAACCTGAATGACGATGACTGCGAGCAGCGCATCGTCCAGGCGAA
AGCAGCGCTGGGAAGGCGCGCGGTAATACTCGCCCATCATTATCAGCGCCCGGATGTTTACAAACACGCCGATCTTACCG
GGGATTCACTGCAGCTCTCGCGCCTTGCTTCAGGGACCGATGCGGATTACCTGGTGTTCTGCGGCGTGCATTTCATGGCC
GAAGTGGCCGATATTCTTTCCAAGCCCGAGCAGATCACCATTCTGCCCGATCTTTCCGCGGGTTGCTCCATGGCGGATAT
GGCGAGTCTTCTCAAGGTGCAGCGCGCGTGGCATGAGCTCTCGGAAGTGCTCGATCCCGATGAAGTGGTCACGCCGGTAA
CTTACATCAACTCTGCCGCTGATCTCAAAGCTTTCTGCGGTGAACACGGCGGCATTGTCTGCACATCCAGCAATGCCATG
AAAATTTTGCAGTGGTCCTTTTCCCGCAGGGAAAAAGTACTGTTTTTTCCGGATCAGCACTTGGGGCGCTGGAGCGGGCA
CAAGCTGGATATTCCACTCGAACAGATGGCGGTGTGGGATTTCGATGAACCCATGGGTGGGCTTTCGCCCGAGCAGATCA
GGAATGCGAAAATCCTCTTGTGGAAGGGGCATTGCTCCGTACACCAGATGTTCCAGCCCCAGCACATACTTCGTTTTCGC
AACCAGCACCCCGAGGGGAAAGTGATTTCGCATCCCGAGTGCAGTTTCGAGGTATGTAAAAACTCGGATTACGTTGGCTC
CACCGACTATATCATCAGGACCATCCGGGAAGCGGAGCCTGGAACACGCTGGCTGGTGGGAACGGAGCTGAACCTGGTCA
ATCGTATTGCCGAGGAATTCAAGGCCCAGGGAAAAATCGTCCAGTTCATGGCATCGACGATCTGCATGTGTTCCACCATG
GCGCGCATCGATCCGCAGCACCTGGCCTGGGCGCTGGAAAACCTGGTTGCGGGGAAGGTGGTAAATCAGATCAAAGTGCC
GGCAGCCGATGCAGTTCTGGCGAAACGTGCCCTGGAGCGCATGCTTGAGGTTTCGCGATAA

Upstream 100 bases:

>100_bases
GCGGGTATGCGGGTCCAATAGTACGTTTGGAACCTCTGCAGTTTCTTATTACCTCTGTCTTATATTACCTGCGGTTTTTA
AAGGAAAAACGGAGTAGGCC

Downstream 100 bases:

>100_bases
TGAAAAAATACAATTGCGCCCCGTCCCGTTCGTCATATGCTCAATAAGCTGCATATCGCTACCTATAACATTCACAAAGG
GTTTTCTCATTTCAATCGGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQAEAIAFERFDNLNDDDCEQRIVQAKAALGRRAVILAHHYQRPDVYKHADLTGDSLQLSRLASGTDADYLVFCGVHFMA
EVADILSKPEQITILPDLSAGCSMADMASLLKVQRAWHELSEVLDPDEVVTPVTYINSAADLKAFCGEHGGIVCTSSNAM
KILQWSFSRREKVLFFPDQHLGRWSGHKLDIPLEQMAVWDFDEPMGGLSPEQIRNAKILLWKGHCSVHQMFQPQHILRFR
NQHPEGKVISHPECSFEVCKNSDYVGSTDYIIRTIREAEPGTRWLVGTELNLVNRIAEEFKAQGKIVQFMASTICMCSTM
ARIDPQHLAWALENLVAGKVVNQIKVPAADAVLAKRALERMLEVSR

Sequences:

>Translated_366_residues
MQAEAIAFERFDNLNDDDCEQRIVQAKAALGRRAVILAHHYQRPDVYKHADLTGDSLQLSRLASGTDADYLVFCGVHFMA
EVADILSKPEQITILPDLSAGCSMADMASLLKVQRAWHELSEVLDPDEVVTPVTYINSAADLKAFCGEHGGIVCTSSNAM
KILQWSFSRREKVLFFPDQHLGRWSGHKLDIPLEQMAVWDFDEPMGGLSPEQIRNAKILLWKGHCSVHQMFQPQHILRFR
NQHPEGKVISHPECSFEVCKNSDYVGSTDYIIRTIREAEPGTRWLVGTELNLVNRIAEEFKAQGKIVQFMASTICMCSTM
ARIDPQHLAWALENLVAGKVVNQIKVPAADAVLAKRALERMLEVSR
>Mature_366_residues
MQAEAIAFERFDNLNDDDCEQRIVQAKAALGRRAVILAHHYQRPDVYKHADLTGDSLQLSRLASGTDADYLVFCGVHFMA
EVADILSKPEQITILPDLSAGCSMADMASLLKVQRAWHELSEVLDPDEVVTPVTYINSAADLKAFCGEHGGIVCTSSNAM
KILQWSFSRREKVLFFPDQHLGRWSGHKLDIPLEQMAVWDFDEPMGGLSPEQIRNAKILLWKGHCSVHQMFQPQHILRFR
NQHPEGKVISHPECSFEVCKNSDYVGSTDYIIRTIREAEPGTRWLVGTELNLVNRIAEEFKAQGKIVQFMASTICMCSTM
ARIDPQHLAWALENLVAGKVVNQIKVPAADAVLAKRALERMLEVSR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=269, Percent_Identity=30.8550185873606, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 41111; Mature: 41111

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAEAIAFERFDNLNDDDCEQRIVQAKAALGRRAVILAHHYQRPDVYKHADLTGDSLQLS
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHH
RLASGTDADYLVFCGVHFMAEVADILSKPEQITILPDLSAGCSMADMASLLKVQRAWHEL
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
SEVLDPDEVVTPVTYINSAADLKAFCGEHGGIVCTSSNAMKILQWSFSRREKVLFFPDQH
HHHCCCHHHHCHHHHHCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCHH
LGRWSGHKLDIPLEQMAVWDFDEPMGGLSPEQIRNAKILLWKGHCSVHQMFQPQHILRFR
CCCCCCCEECCCHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCCHHHHCCHHHHHHHH
NQHPEGKVISHPECSFEVCKNSDYVGSTDYIIRTIREAEPGTRWLVGTELNLVNRIAEEF
CCCCCCCEECCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
KAQGKIVQFMASTICMCSTMARIDPQHLAWALENLVAGKVVNQIKVPAADAVLAKRALER
HHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MLEVSR
HHHHCC
>Mature Secondary Structure
MQAEAIAFERFDNLNDDDCEQRIVQAKAALGRRAVILAHHYQRPDVYKHADLTGDSLQLS
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHH
RLASGTDADYLVFCGVHFMAEVADILSKPEQITILPDLSAGCSMADMASLLKVQRAWHEL
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
SEVLDPDEVVTPVTYINSAADLKAFCGEHGGIVCTSSNAMKILQWSFSRREKVLFFPDQH
HHHCCCHHHHCHHHHHCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCHH
LGRWSGHKLDIPLEQMAVWDFDEPMGGLSPEQIRNAKILLWKGHCSVHQMFQPQHILRFR
CCCCCCCEECCCHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCCHHHHCCHHHHHHHH
NQHPEGKVISHPECSFEVCKNSDYVGSTDYIIRTIREAEPGTRWLVGTELNLVNRIAEEF
CCCCCCCEECCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
KAQGKIVQFMASTICMCSTMARIDPQHLAWALENLVAGKVVNQIKVPAADAVLAKRALER
HHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MLEVSR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA