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The map label for this gene is polA [H]

Identifier: 82701702

GI number: 82701702

Start: 653959

End: 656676

Strand: Direct

Name: polA [H]

Synonym: Nmul_A0568

Alternate gene names: 82701702

Gene position: 653959-656676 (Clockwise)

Preceding gene: 82701697

Following gene: 82701703

Centisome position: 20.54

GC content: 56.81

Gene sequence:

>2718_bases
ATGAAAACACTACTGCTGGTCGATGGTTCATCTTATCTGTATCGCGCTTTTCACGCGCTGCCCGATTTCCGCAACCGCAA
TAACGAGCCGACCGGTGCAGTCTATGGCGTGCTGAATATGCTGCGCCGCTTGCACAAGGATTATCAGGCCGATTATAGCG
CTTGCGTATTTGATGCAAAAGGCAAGACTTTCCGCGATGAGCTCTACGCCGAGTACAAGGCGAACCGGCCGCCCATGCCC
GACGAGCTTGCCGCCCAGATTGCGCCGCTCCTGGAATGCATAAATGCAATGGGATGGCCGATGCTTTCTGTGGAAGGAGT
AGAGGCGGACGATGTGATCGGCACGCTGGTGAAACAGGCCGAAGGCGAGAACATGCGCTGCATCATTTCGACTGGCGATA
AAGACATTGCGCAACTGGTGAACCCCCAAGTGACCCTCGTCAATACCATGACGAATGAAATGCTTGATGAAGCCGGTGTG
CTTGGACGTTTCGGCGTACCTCCGGAACGCATGCTCGACTATCTGGCGCTGGTGGGTGACGCGGTCGACAACATCCCCGG
CGTAGCGAAGGTGGGACCAAAAACCGCGGTGAAGTGGCTCAATCAATATGGGACACTCGATAACTTGCTTGTCCATGCTG
GCGAAATAGGCGGCGTAGTAGGGGAGAATCTGCGCAATGCGCTGGGCTGGTTGAGCAGATCGCGGCAACTGCTCTCCATC
AAGTGCGACGTTTCGTTGCCGGTCAGCCTGCATGATCTCGGACCCCAGCCCCCTGACATGGTAAAGCTCGCGGAGTTGTA
CGAGCGGCTGGACTTCAAGAGCTGGTTGCGCGAATTGCAACAGGAATCCCAGGCGGAAGGAGCCGCTGATGCGCTTTCTC
GGGGTTTTGCCCCGGCAGGCTCGAATCTGGTGCAGGCCGATTATCAGACCATTCTTACTCCCGAGCAACTCGATGAGTGG
ATGATGCGAATCGCCGCGGCGCCGCTCGCCTCACTCGACACCGAAACGACGGGGCTTGATCCGATGCGCGCCGAGCTGGT
GGGTATCTCGTTTTCCGTGGAACCGCATCACGGGGCCTATATACCGCTGGGACATCGTTATACCGGTGTCCCCCGCCAGT
TGCCGCTCGACTTTGTGCTCGAAAAGCTCAAACCCTGGCTGACAGACCCTTCCGCCCCCAAACTGGGGCAGAACCTGAAG
TTTGACAGGCACGTGTTCGCCAACCACGGCATCGGGTTGAAAGGAATCGTTCACGATACGCTGCTGCAATCCTATGTCTT
CGAATCCCATCGCCCGCACGATATGGACAACCTTGCGCTGCGGCATCTGGGGATCAAAACCATCACCTATGATGAAGTCA
CCGGCAAGGGAGCCGCCCGAATAGGTTTCGAGCAGGTGGATATCGAACGCGCTGCGCAATATGCAGCCGAGGACGCGGAT
GTCACGCTGCAGCTGCACCAGCACCTGTATGCTGAAGTTGGCAAGGATGCAAAGCTCGATCATATCTATCGCACGCTGGA
AATGCCCGTGATGGATGTCCTGTTCGAGATGGAGCGCAACGGGGTGCTCCTGGATATCAAATTGCTGGAAACGCAAAGCC
GCGAGCTCGGCGAGAAAATGCTGGCGCTGGAGGAGCGCGCCTGCACCATTGCCGGGCTGCCATTCAACCTGAATTCACCC
AAACAGATTCAGGAAATCCTGTTTGACAGACTCAAGCTGCCTGTCATGAAAAAAACACCGAGCGGCGTTCCTTCCACCGA
CGAAGATGTACTGCAGAAACTTGCACTTGATTATCCCCTCGCCAGGGCTCTGCTGGATTATCGGGGTCTTGCCAAACTCA
AGTCGACTTACACCGACAAGCTGCCGCGCATGGTGCATCCCGTTACTGGAAGAGTGCACACCAATTATGCCCAGGCTGTG
GCGGTGACGGGCAGACTCGCCAGTAACGAACCGAACTTGCAGAACATACCCATCCGCACTGCCGAAGGGCGGCGTATCCG
GGAAGCGTTCATTGCCCCGAGCGGATACAGAATCATTTCCGCGGATTATTCACAGATCGAATTACGCATCATGGCGCACA
TTTCGCAGGATGCCGGACTGCTCAAGGCCTTTGCACAAGGGGAAGACATCCATCGCGCCACGGGCTCCGAGATATTCGGC
GTTCCCCTGGAAACAGTGAACAGCGAACAGCGCAGGTATGCAAAAATCATCAATTTCGGCCTGATCTACGGTATGTCGGA
ATTCGGACTCGCGACGCAACTGGGGATTGAGCGGGCCGCGGCCAGAACCTATATGGACCGCTACTTTTCCCGCTATCCGG
GAGTGGCGGACTACATGCAGCGGACACGGAAAACCGCCAGGGAAAACCGCTATGTGGAGACCGTTTTCGGGCGGCGGCTG
TGGTTGTCGGAGATCAACAGTTCCAACGGCATGCGTCGTCAGGCGGCGGAACGCGCTGCCATCAACGCGCCCATGCAGGG
TACTGCCGCCGATATCATCAAGCTTGCCATGATAGAAGTGCATGACTGGCTGCGGCGGCATGAACTGCGCAGCAAACTCG
TCATGCAGGTCCATGACGAACTGGTGTTGGAGGTGCCGGAAAACGAAATCGAGACCATAAAGCGCGAGTTGCCGTTGCTC
ATGGGCAATGTGGCGCAACTTCAGGTGCCGTTATTGGTGGAAGTAGGCGTCGGGCCAAATTGGGAGCAGGCCCACTGA

Upstream 100 bases:

>100_bases
GCCAGGATTCACGTCCTGACCATGCCTTCTCCTGGAAATCGTTTGTCATGGTACGGGCTGCTTTGTTTTTCAGGCTCATC
GGAAAACCTTTGGAAGTTAA

Downstream 100 bases:

>100_bases
ACACAGGGGTGAAAAGAGCGGGAAGGGGAGAAGTATTGCTTGCTAAATTGCTGAAAATTGCCGTAAAATCACCCCCTTTT
CGGTTTTGGACCTCCACAGG

Product: DNA polymerase I

Products: NA

Alternate protein names: POL I [H]

Number of amino acids: Translated: 905; Mature: 905

Protein sequence:

>905_residues
MKTLLLVDGSSYLYRAFHALPDFRNRNNEPTGAVYGVLNMLRRLHKDYQADYSACVFDAKGKTFRDELYAEYKANRPPMP
DELAAQIAPLLECINAMGWPMLSVEGVEADDVIGTLVKQAEGENMRCIISTGDKDIAQLVNPQVTLVNTMTNEMLDEAGV
LGRFGVPPERMLDYLALVGDAVDNIPGVAKVGPKTAVKWLNQYGTLDNLLVHAGEIGGVVGENLRNALGWLSRSRQLLSI
KCDVSLPVSLHDLGPQPPDMVKLAELYERLDFKSWLRELQQESQAEGAADALSRGFAPAGSNLVQADYQTILTPEQLDEW
MMRIAAAPLASLDTETTGLDPMRAELVGISFSVEPHHGAYIPLGHRYTGVPRQLPLDFVLEKLKPWLTDPSAPKLGQNLK
FDRHVFANHGIGLKGIVHDTLLQSYVFESHRPHDMDNLALRHLGIKTITYDEVTGKGAARIGFEQVDIERAAQYAAEDAD
VTLQLHQHLYAEVGKDAKLDHIYRTLEMPVMDVLFEMERNGVLLDIKLLETQSRELGEKMLALEERACTIAGLPFNLNSP
KQIQEILFDRLKLPVMKKTPSGVPSTDEDVLQKLALDYPLARALLDYRGLAKLKSTYTDKLPRMVHPVTGRVHTNYAQAV
AVTGRLASNEPNLQNIPIRTAEGRRIREAFIAPSGYRIISADYSQIELRIMAHISQDAGLLKAFAQGEDIHRATGSEIFG
VPLETVNSEQRRYAKIINFGLIYGMSEFGLATQLGIERAAARTYMDRYFSRYPGVADYMQRTRKTARENRYVETVFGRRL
WLSEINSSNGMRRQAAERAAINAPMQGTAADIIKLAMIEVHDWLRRHELRSKLVMQVHDELVLEVPENEIETIKRELPLL
MGNVAQLQVPLLVEVGVGPNWEQAH

Sequences:

>Translated_905_residues
MKTLLLVDGSSYLYRAFHALPDFRNRNNEPTGAVYGVLNMLRRLHKDYQADYSACVFDAKGKTFRDELYAEYKANRPPMP
DELAAQIAPLLECINAMGWPMLSVEGVEADDVIGTLVKQAEGENMRCIISTGDKDIAQLVNPQVTLVNTMTNEMLDEAGV
LGRFGVPPERMLDYLALVGDAVDNIPGVAKVGPKTAVKWLNQYGTLDNLLVHAGEIGGVVGENLRNALGWLSRSRQLLSI
KCDVSLPVSLHDLGPQPPDMVKLAELYERLDFKSWLRELQQESQAEGAADALSRGFAPAGSNLVQADYQTILTPEQLDEW
MMRIAAAPLASLDTETTGLDPMRAELVGISFSVEPHHGAYIPLGHRYTGVPRQLPLDFVLEKLKPWLTDPSAPKLGQNLK
FDRHVFANHGIGLKGIVHDTLLQSYVFESHRPHDMDNLALRHLGIKTITYDEVTGKGAARIGFEQVDIERAAQYAAEDAD
VTLQLHQHLYAEVGKDAKLDHIYRTLEMPVMDVLFEMERNGVLLDIKLLETQSRELGEKMLALEERACTIAGLPFNLNSP
KQIQEILFDRLKLPVMKKTPSGVPSTDEDVLQKLALDYPLARALLDYRGLAKLKSTYTDKLPRMVHPVTGRVHTNYAQAV
AVTGRLASNEPNLQNIPIRTAEGRRIREAFIAPSGYRIISADYSQIELRIMAHISQDAGLLKAFAQGEDIHRATGSEIFG
VPLETVNSEQRRYAKIINFGLIYGMSEFGLATQLGIERAAARTYMDRYFSRYPGVADYMQRTRKTARENRYVETVFGRRL
WLSEINSSNGMRRQAAERAAINAPMQGTAADIIKLAMIEVHDWLRRHELRSKLVMQVHDELVLEVPENEIETIKRELPLL
MGNVAQLQVPLLVEVGVGPNWEQAH
>Mature_905_residues
MKTLLLVDGSSYLYRAFHALPDFRNRNNEPTGAVYGVLNMLRRLHKDYQADYSACVFDAKGKTFRDELYAEYKANRPPMP
DELAAQIAPLLECINAMGWPMLSVEGVEADDVIGTLVKQAEGENMRCIISTGDKDIAQLVNPQVTLVNTMTNEMLDEAGV
LGRFGVPPERMLDYLALVGDAVDNIPGVAKVGPKTAVKWLNQYGTLDNLLVHAGEIGGVVGENLRNALGWLSRSRQLLSI
KCDVSLPVSLHDLGPQPPDMVKLAELYERLDFKSWLRELQQESQAEGAADALSRGFAPAGSNLVQADYQTILTPEQLDEW
MMRIAAAPLASLDTETTGLDPMRAELVGISFSVEPHHGAYIPLGHRYTGVPRQLPLDFVLEKLKPWLTDPSAPKLGQNLK
FDRHVFANHGIGLKGIVHDTLLQSYVFESHRPHDMDNLALRHLGIKTITYDEVTGKGAARIGFEQVDIERAAQYAAEDAD
VTLQLHQHLYAEVGKDAKLDHIYRTLEMPVMDVLFEMERNGVLLDIKLLETQSRELGEKMLALEERACTIAGLPFNLNSP
KQIQEILFDRLKLPVMKKTPSGVPSTDEDVLQKLALDYPLARALLDYRGLAKLKSTYTDKLPRMVHPVTGRVHTNYAQAV
AVTGRLASNEPNLQNIPIRTAEGRRIREAFIAPSGYRIISADYSQIELRIMAHISQDAGLLKAFAQGEDIHRATGSEIFG
VPLETVNSEQRRYAKIINFGLIYGMSEFGLATQLGIERAAARTYMDRYFSRYPGVADYMQRTRKTARENRYVETVFGRRL
WLSEINSSNGMRRQAAERAAINAPMQGTAADIIKLAMIEVHDWLRRHELRSKLVMQVHDELVLEVPENEIETIKRELPLL
MGNVAQLQVPLLVEVGVGPNWEQAH

Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template [H]

COG id: COG0749

COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI112420958, Length=439, Percent_Identity=33.2574031890661, Blast_Score=224, Evalue=4e-58,
Organism=Homo sapiens, GI139394648, Length=560, Percent_Identity=27.3214285714286, Blast_Score=204, Evalue=5e-52,
Organism=Escherichia coli, GI1790294, Length=920, Percent_Identity=54.5652173913043, Blast_Score=961, Evalue=0.0,
Organism=Escherichia coli, GI226510970, Length=209, Percent_Identity=32.0574162679426, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI86563272, Length=406, Percent_Identity=28.3251231527094, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI17933644, Length=465, Percent_Identity=29.4623655913978, Blast_Score=189, Evalue=9e-48,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR019760
- InterPro:   IPR001098
- InterPro:   IPR018320
- InterPro:   IPR002298
- InterPro:   IPR008918
- InterPro:   IPR003583
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 101186; Mature: 101186

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00447 DNA_POLYMERASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLLVDGSSYLYRAFHALPDFRNRNNEPTGAVYGVLNMLRRLHKDYQADYSACVFDAK
CCEEEEECCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GKTFRDELYAEYKANRPPMPDELAAQIAPLLECINAMGWPMLSVEGVEADDVIGTLVKQA
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHC
EGENMRCIISTGDKDIAQLVNPQVTLVNTMTNEMLDEAGVLGRFGVPPERMLDYLALVGD
CCCCCEEEEECCCHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AVDNIPGVAKVGPKTAVKWLNQYGTLDNLLVHAGEIGGVVGENLRNALGWLSRSRQLLSI
HHHCCCCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEE
KCDVSLPVSLHDLGPQPPDMVKLAELYERLDFKSWLRELQQESQAEGAADALSRGFAPAG
EECCCCCEEHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
SNLVQADYQTILTPEQLDEWMMRIAAAPLASLDTETTGLDPMRAELVGISFSVEPHHGAY
CCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHEEEEEEEECCCCCCE
IPLGHRYTGVPRQLPLDFVLEKLKPWLTDPSAPKLGQNLKFDRHVFANHGIGLKGIVHDT
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHH
LLQSYVFESHRPHDMDNLALRHLGIKTITYDEVTGKGAARIGFEQVDIERAAQYAAEDAD
HHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHCCCCC
VTLQLHQHLYAEVGKDAKLDHIYRTLEMPVMDVLFEMERNGVLLDIKLLETQSRELGEKM
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHH
LALEERACTIAGLPFNLNSPKQIQEILFDRLKLPVMKKTPSGVPSTDEDVLQKLALDYPL
HHHHHCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHH
ARALLDYRGLAKLKSTYTDKLPRMVHPVTGRVHTNYAQAVAVTGRLASNEPNLQNIPIRT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCCCCCCCCCCEEC
AEGRRIREAFIAPSGYRIISADYSQIELRIMAHISQDAGLLKAFAQGEDIHRATGSEIFG
CCCCHHHHHHCCCCCCEEEECCCHHHEEHHEEHHCCCHHHHHHHHCCCHHHHHCCCCEEC
VPLETVNSEQRRYAKIINFGLIYGMSEFGLATQLGIERAAARTYMDRYFSRYPGVADYMQ
CCHHHCCHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RTRKTARENRYVETVFGRRLWLSEINSSNGMRRQAAERAAINAPMQGTAADIIKLAMIEV
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
HDWLRRHELRSKLVMQVHDELVLEVPENEIETIKRELPLLMGNVAQLQVPLLVEVGVGPN
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCC
WEQAH
CCCCC
>Mature Secondary Structure
MKTLLLVDGSSYLYRAFHALPDFRNRNNEPTGAVYGVLNMLRRLHKDYQADYSACVFDAK
CCEEEEECCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GKTFRDELYAEYKANRPPMPDELAAQIAPLLECINAMGWPMLSVEGVEADDVIGTLVKQA
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHC
EGENMRCIISTGDKDIAQLVNPQVTLVNTMTNEMLDEAGVLGRFGVPPERMLDYLALVGD
CCCCCEEEEECCCHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AVDNIPGVAKVGPKTAVKWLNQYGTLDNLLVHAGEIGGVVGENLRNALGWLSRSRQLLSI
HHHCCCCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEE
KCDVSLPVSLHDLGPQPPDMVKLAELYERLDFKSWLRELQQESQAEGAADALSRGFAPAG
EECCCCCEEHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
SNLVQADYQTILTPEQLDEWMMRIAAAPLASLDTETTGLDPMRAELVGISFSVEPHHGAY
CCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHEEEEEEEECCCCCCE
IPLGHRYTGVPRQLPLDFVLEKLKPWLTDPSAPKLGQNLKFDRHVFANHGIGLKGIVHDT
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHH
LLQSYVFESHRPHDMDNLALRHLGIKTITYDEVTGKGAARIGFEQVDIERAAQYAAEDAD
HHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHCCCCC
VTLQLHQHLYAEVGKDAKLDHIYRTLEMPVMDVLFEMERNGVLLDIKLLETQSRELGEKM
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHH
LALEERACTIAGLPFNLNSPKQIQEILFDRLKLPVMKKTPSGVPSTDEDVLQKLALDYPL
HHHHHCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHH
ARALLDYRGLAKLKSTYTDKLPRMVHPVTGRVHTNYAQAVAVTGRLASNEPNLQNIPIRT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCCCCCCCCCCEEC
AEGRRIREAFIAPSGYRIISADYSQIELRIMAHISQDAGLLKAFAQGEDIHRATGSEIFG
CCCCHHHHHHCCCCCCEEEECCCHHHEEHHEEHHCCCHHHHHHHHCCCHHHHHCCCCEEC
VPLETVNSEQRRYAKIINFGLIYGMSEFGLATQLGIERAAARTYMDRYFSRYPGVADYMQ
CCHHHCCHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RTRKTARENRYVETVFGRRLWLSEINSSNGMRRQAAERAAINAPMQGTAADIIKLAMIEV
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
HDWLRRHELRSKLVMQVHDELVLEVPENEIETIKRELPLLMGNVAQLQVPLLVEVGVGPN
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCC
WEQAH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6276402; 8346018; 9278503; 6183253; 6302278; 7035456; 3883192; 1989886; 8469987; 8260491; 9514742; 9888810; 10588690; 8442659 [H]