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The map label for this gene is gmhB [H]

Identifier: 82701683

GI number: 82701683

Start: 633617

End: 634150

Strand: Reverse

Name: gmhB [H]

Synonym: Nmul_A0549

Alternate gene names: 82701683

Gene position: 634150-633617 (Counterclockwise)

Preceding gene: 82701684

Following gene: 82701682

Centisome position: 19.92

GC content: 57.12

Gene sequence:

>534_bases
ATGAAACTCGTCATTCTCGACCGGGACGGCGTCATCAATTACGACAGTGCCGCCTTTATCAAGACGCCGGACGAATGGAA
GCCGATTCCCCGCAGTCTTGAAGCAATCGCGCACCTTACGCAGGCGGGCTATCGGGTGGTGGTCGCCACCAACCAGTCGG
GCATTGGCAGAGGTTTGCTGGACATGGTGTCATTCAATGCCATCAATGACAAGATGTGCAAAGCCGCGGTCCAGGCAGGA
GGACGCATCGATGCGATATTTTTCTGCCCCCATGCCCACACCGACAACTGCGATTGCCGCAAGCCCGCTACGGGGATGTT
CAAGGAAATTTCAGAACGTTTCGGGCTGGACTTGAAAGGTGTGCCTGCGATCGGCGATTCCCTGCGTGATTTGCAGTGCG
CAGCTGCCGTCGGCGCGCTTCCCGTCCTGGTGCTGACCGGCAAAGGAAAAAAGACCGAAGCCGAGGATGACCTGCCCGAA
AACACAAAAATATTCGCCGATCTCTCGGCGGCGGTCAATGCCCTGACGCAATGA

Upstream 100 bases:

>100_bases
GCTGCGCCATAACCGCCTGGCCCTGCTTGCGCAAATGCAGAAGATAATGAACCGGATTGCGGATATTTCCCGGCTGGCGC
TCTGATACCGGCAACCGATC

Downstream 100 bases:

>100_bases
ACTGGATTCCGGTCGTGCTGCGCTCGACGCTCTACGCGCTGCTGCAGCTCATCATCACCCCTTTCTACTTCCTGATCGTC
TTTGCCGCCTTCCCACTTTC

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MKLVILDRDGVINYDSAAFIKTPDEWKPIPRSLEAIAHLTQAGYRVVVATNQSGIGRGLLDMVSFNAINDKMCKAAVQAG
GRIDAIFFCPHAHTDNCDCRKPATGMFKEISERFGLDLKGVPAIGDSLRDLQCAAAVGALPVLVLTGKGKKTEAEDDLPE
NTKIFADLSAAVNALTQ

Sequences:

>Translated_177_residues
MKLVILDRDGVINYDSAAFIKTPDEWKPIPRSLEAIAHLTQAGYRVVVATNQSGIGRGLLDMVSFNAINDKMCKAAVQAG
GRIDAIFFCPHAHTDNCDCRKPATGMFKEISERFGLDLKGVPAIGDSLRDLQCAAAVGALPVLVLTGKGKKTEAEDDLPE
NTKIFADLSAAVNALTQ
>Mature_177_residues
MKLVILDRDGVINYDSAAFIKTPDEWKPIPRSLEAIAHLTQAGYRVVVATNQSGIGRGLLDMVSFNAINDKMCKAAVQAG
GRIDAIFFCPHAHTDNCDCRKPATGMFKEISERFGLDLKGVPAIGDSLRDLQCAAAVGALPVLVLTGKGKKTEAEDDLPE
NTKIFADLSAAVNALTQ

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=177, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87082027, Length=143, Percent_Identity=30.0699300699301, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 18958; Mature: 18958

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVILDRDGVINYDSAAFIKTPDEWKPIPRSLEAIAHLTQAGYRVVVATNQSGIGRGLL
CEEEEECCCCEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
DMVSFNAINDKMCKAAVQAGGRIDAIFFCPHAHTDNCDCRKPATGMFKEISERFGLDLKG
HHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
VPAIGDSLRDLQCAAAVGALPVLVLTGKGKKTEAEDDLPENTKIFADLSAAVNALTQ
CCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLVILDRDGVINYDSAAFIKTPDEWKPIPRSLEAIAHLTQAGYRVVVATNQSGIGRGLL
CEEEEECCCCEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
DMVSFNAINDKMCKAAVQAGGRIDAIFFCPHAHTDNCDCRKPATGMFKEISERFGLDLKG
HHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
VPAIGDSLRDLQCAAAVGALPVLVLTGKGKKTEAEDDLPENTKIFADLSAAVNALTQ
CCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]