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The map label for this gene is infC [H]

Identifier: 82701622

GI number: 82701622

Start: 547978

End: 548532

Strand: Direct

Name: infC [H]

Synonym: Nmul_A0488

Alternate gene names: 82701622

Gene position: 547978-548532 (Clockwise)

Preceding gene: 82701621

Following gene: 82701623

Centisome position: 17.21

GC content: 50.09

Gene sequence:

>555_bases
GTGCGCTTGATTGGTGCGGATGGAGAGCAGATAGGTATAGTCCCTCTGGCGGTTGCCAATAATCTGGCGGAAGAAGCAGA
GGTGGATTTGGTTGAAATCGCCCCTACTGCCAAACCCCCTGTATGCCGCCTGATGGATTATGGCAAGTTCAGGTATCAGG
AAAGCAAGAAAAAGCACGAAGCCAAGCTCAAGCAAAAACAGATTCAGATCAAGGAAGTCAAGTTTCGTCCCAATACGGAC
GAGGGTGATTACAACATCAAGCTGCGTAACCTGATCAGTTTTCTGGACGAGGGCGATAAAGCCAAAATTACCCTCCGCTT
CCGCGGGCGGGAAATGGCGCATCAGGAATTTGGAGTGCGGTTGCTGGAGCGGATAAAAGGCGATCTGGAATCGCATGCGA
TAGTGGAGCAATTTCCCAAAATGGAGGGACGCCAGATGGTGATGGTGTTATCTCCACGAAAGAAAGAAATAAAGAACTCC
AAAGAAGTAAAAACCTCCAACTCAAAGGAAACAAAACCGACGGCTGATGCCGAAAGCCAGCCCGAGCGGCGCTAG

Upstream 100 bases:

>100_bases
GCACCCGGGCGGGGGCGGCCTGATTTATTAATAGAGTTCGGGAGTTACTATAGTTCAAGAAAAAGCAGCACGCATCAATT
ACGAGATTACTGCGCCGGAA

Downstream 100 bases:

>100_bases
TGCACTCATTTCCACTGATTTCAGGTTCATCCGGTACCGCGATTTGTACCTGTACCTGCTGGATAGATCGGAAGATGCGA
GGCTGGGATAGTGTTCAGGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MRLIGADGEQIGIVPLAVANNLAEEAEVDLVEIAPTAKPPVCRLMDYGKFRYQESKKKHEAKLKQKQIQIKEVKFRPNTD
EGDYNIKLRNLISFLDEGDKAKITLRFRGREMAHQEFGVRLLERIKGDLESHAIVEQFPKMEGRQMVMVLSPRKKEIKNS
KEVKTSNSKETKPTADAESQPERR

Sequences:

>Translated_184_residues
MRLIGADGEQIGIVPLAVANNLAEEAEVDLVEIAPTAKPPVCRLMDYGKFRYQESKKKHEAKLKQKQIQIKEVKFRPNTD
EGDYNIKLRNLISFLDEGDKAKITLRFRGREMAHQEFGVRLLERIKGDLESHAIVEQFPKMEGRQMVMVLSPRKKEIKNS
KEVKTSNSKETKPTADAESQPERR
>Mature_184_residues
MRLIGADGEQIGIVPLAVANNLAEEAEVDLVEIAPTAKPPVCRLMDYGKFRYQESKKKHEAKLKQKQIQIKEVKFRPNTD
EGDYNIKLRNLISFLDEGDKAKITLRFRGREMAHQEFGVRLLERIKGDLESHAIVEQFPKMEGRQMVMVLSPRKKEIKNS
KEVKTSNSKETKPTADAESQPERR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=157, Percent_Identity=66.8789808917197, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21103; Mature: 21103

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIGADGEQIGIVPLAVANNLAEEAEVDLVEIAPTAKPPVCRLMDYGKFRYQESKKKHE
CEEECCCCCEEEEEHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHH
AKLKQKQIQIKEVKFRPNTDEGDYNIKLRNLISFLDEGDKAKITLRFRGREMAHQEFGVR
HHHHHHHHEEEEEEECCCCCCCCEEEEHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
LLERIKGDLESHAIVEQFPKMEGRQMVMVLSPRKKEIKNSKEVKTSNSKETKPTADAESQ
HHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCHHCCCCCCCCCCCCCCCCCC
PERR
CCCC
>Mature Secondary Structure
MRLIGADGEQIGIVPLAVANNLAEEAEVDLVEIAPTAKPPVCRLMDYGKFRYQESKKKHE
CEEECCCCCEEEEEHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHH
AKLKQKQIQIKEVKFRPNTDEGDYNIKLRNLISFLDEGDKAKITLRFRGREMAHQEFGVR
HHHHHHHHEEEEEEECCCCCCCCEEEEHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
LLERIKGDLESHAIVEQFPKMEGRQMVMVLSPRKKEIKNSKEVKTSNSKETKPTADAESQ
HHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCCHHCCCCCCCCCCCCCCCCCC
PERR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]