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The map label for this gene is dapB

Identifier: 82701611

GI number: 82701611

Start: 532666

End: 533475

Strand: Direct

Name: dapB

Synonym: Nmul_A0477

Alternate gene names: 82701611

Gene position: 532666-533475 (Clockwise)

Preceding gene: 82701610

Following gene: 82701612

Centisome position: 16.73

GC content: 58.02

Gene sequence:

>810_bases
ATGTCGACATTGAATATTGCTGTGGCTGGAAGTTCCGGGCGCATGGGACGCGCCTTACTGGAGGCCGTTGAACGGGCTCC
GGACATGCGCTTGAGCGCCGCTCTCGAGCGGAGCGGGAGTCCTTACCTTGGAAAGGACGCGGGAGAGTTGATCGGGTCGC
CCTGCGGTATTGGGATAACCGATAACGTCGATACGGCGCTTGATGGAAGCCAAGTGCTGGTAGACTTTACCCGCCCGGAC
GGGACGCTGGTTCACGTTGACCGGTGCCGTGAGAAAAACATAAAAATGGTAATCGGCACAACCGGCTTTTCGCCCCGGCA
GAAAGAAGCGCTCTGGATCGCCTCACGGGACATTGCCATCGTGCTGGCGCCTAATATGAGCGTGGGCGTGAATGTCACTC
TGAAACTGCTGGAGACGGCGGCCAGGGTCCTGAATGAGGATTATGACATAGAAATTATCGAGGCCCATCATCGCCACAAG
GTGGATGCTCCTTCCGGCACTGCGCTGCTGATGGGCGAGGTAGTGGCAAAAGCGCTGGGTAAAGAGCTTTCCGAGGTCGC
CGTTTACAGTCGCGAGGGCCATACGGGTGAGCGGGAGGCAGGTTCCATCGGCTTTGCTACCGTTCGCGGCGGGGATATCG
TAGGGGATCATACCGTCATGTTCGCAGGAACCGGCGAACGTATCGAAATTTCCCATAAGGCAAGCAGCCGCGCGACATTT
GCCGAGGGTGCGTTGAGAGCTGCCCGCTTTCTCGCGGATAAACGGAACGGCATGTTCGACATGCAGGACGTCTTGGGACT
CAGGCAGTAA

Upstream 100 bases:

>100_bases
AAGTGCCCTCCCAGGCGACGGATACCGGAATCATGGATGCGGATCAGCCAAAGGAATAGGACAATTTTGCAAGTCAGTTT
ATCAGACTATCAGACAAGGA

Downstream 100 bases:

>100_bases
GCGGCGGCCTCGGTGCTCGCATTCGTTCTCGCTTCCAGTGCATTTTCTTCCGAATCCTCCGATCCTCGGGAAGTACATTA
GGGGATTGATCGCACGGATG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSTLNIAVAGSSGRMGRALLEAVERAPDMRLSAALERSGSPYLGKDAGELIGSPCGIGITDNVDTALDGSQVLVDFTRPD
GTLVHVDRCREKNIKMVIGTTGFSPRQKEALWIASRDIAIVLAPNMSVGVNVTLKLLETAARVLNEDYDIEIIEAHHRHK
VDAPSGTALLMGEVVAKALGKELSEVAVYSREGHTGEREAGSIGFATVRGGDIVGDHTVMFAGTGERIEISHKASSRATF
AEGALRAARFLADKRNGMFDMQDVLGLRQ

Sequences:

>Translated_269_residues
MSTLNIAVAGSSGRMGRALLEAVERAPDMRLSAALERSGSPYLGKDAGELIGSPCGIGITDNVDTALDGSQVLVDFTRPD
GTLVHVDRCREKNIKMVIGTTGFSPRQKEALWIASRDIAIVLAPNMSVGVNVTLKLLETAARVLNEDYDIEIIEAHHRHK
VDAPSGTALLMGEVVAKALGKELSEVAVYSREGHTGEREAGSIGFATVRGGDIVGDHTVMFAGTGERIEISHKASSRATF
AEGALRAARFLADKRNGMFDMQDVLGLRQ
>Mature_268_residues
STLNIAVAGSSGRMGRALLEAVERAPDMRLSAALERSGSPYLGKDAGELIGSPCGIGITDNVDTALDGSQVLVDFTRPDG
TLVHVDRCREKNIKMVIGTTGFSPRQKEALWIASRDIAIVLAPNMSVGVNVTLKLLETAARVLNEDYDIEIIEAHHRHKV
DAPSGTALLMGEVVAKALGKELSEVAVYSREGHTGEREAGSIGFATVRGGDIVGDHTVMFAGTGERIEISHKASSRATFA
EGALRAARFLADKRNGMFDMQDVLGLRQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=269, Percent_Identity=59.4795539033457, Blast_Score=298, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_NITMU (Q2YBT6)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411177.1
- HSSP:   Q9X1K8
- ProteinModelPortal:   Q2YBT6
- SMR:   Q2YBT6
- STRING:   Q2YBT6
- GeneID:   3784894
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0477
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q2YBT6
- ProtClustDB:   PRK00048
- BioCyc:   NMUL323848:NMUL_A0477-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28683; Mature: 28552

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLNIAVAGSSGRMGRALLEAVERAPDMRLSAALERSGSPYLGKDAGELIGSPCGIGIT
CCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCC
DNVDTALDGSQVLVDFTRPDGTLVHVDRCREKNIKMVIGTTGFSPRQKEALWIASRDIAI
CCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCEEEEEECCEEE
VLAPNMSVGVNVTLKLLETAARVLNEDYDIEIIEAHHRHKVDAPSGTALLMGEVVAKALG
EECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
KELSEVAVYSREGHTGEREAGSIGFATVRGGDIVGDHTVMFAGTGERIEISHKASSRATF
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEECCCEEEEECCCCEEEEECCCCCCHHH
AEGALRAARFLADKRNGMFDMQDVLGLRQ
HHHHHHHHHHHHHHCCCCCCHHHHHCCCC
>Mature Secondary Structure 
STLNIAVAGSSGRMGRALLEAVERAPDMRLSAALERSGSPYLGKDAGELIGSPCGIGIT
CEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCC
DNVDTALDGSQVLVDFTRPDGTLVHVDRCREKNIKMVIGTTGFSPRQKEALWIASRDIAI
CCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCEEEEEECCEEE
VLAPNMSVGVNVTLKLLETAARVLNEDYDIEIIEAHHRHKVDAPSGTALLMGEVVAKALG
EECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
KELSEVAVYSREGHTGEREAGSIGFATVRGGDIVGDHTVMFAGTGERIEISHKASSRATF
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEECCCEEEEECCCCEEEEECCCCCCHHH
AEGALRAARFLADKRNGMFDMQDVLGLRQ
HHHHHHHHHHHHHHCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA