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The map label for this gene is mreD [H]

Identifier: 82701452

GI number: 82701452

Start: 343570

End: 344091

Strand: Reverse

Name: mreD [H]

Synonym: Nmul_A0318

Alternate gene names: 82701452

Gene position: 344091-343570 (Counterclockwise)

Preceding gene: 82701453

Following gene: 82701451

Centisome position: 10.81

GC content: 54.98

Gene sequence:

>522_bases
GTGACGCTCGCTAATTCATCCAGGCACGAAATTCTGATGCCAGCCAAAAGCTGGTTCATCATGCTCAGCCTGATCGTGGC
GCTACTCCTGAATCTCATACCCGTCACAGGCACCGCTCGGACGCTGCAGCCCGATTTTGTCGCGCTGGTGATGCTTTACT
GGTATCTCAACGAACCCCAGCGTGTGGGCATTGGCATGGCATTCTGGATGGGTCTGCTCATGGATCTGAGCAATGCCAGT
ACCTTCGGGCAACACGCGCTCGGGTACAGCGTAATGGCGTTCATGGCACTGGTCTTCAACCGGCGCATGGGTATCTTCGA
AGGATATAAACAAGCTCCCCAGATAGGACTGGTTCTGCTTTCAGGGCAGATCGTCACACTTCTTGCCGGGCTGTTTGCCG
GTTCTCCTTTCCCCGGCTGGAACTTCTTTCTTGGCAGCATTGTCGGCATGTTACTGTGGCCGCTTCTCTCAGCCATATTG
AGGGTGCCGCAGAAACCCTGGTCTGCTTCCGATGCAAGATGA

Upstream 100 bases:

>100_bases
AGAATCGGCAGCTGTTAATCCTTTCCACGCGGGCGCCTCGTACCGGAACACCGGCAGAAGCGACCAAAACGAAGCCCCGC
CCCCAGGAAGCGAGAAGACA

Downstream 100 bases:

>100_bases
ATCACAGAATCGAGCTTCGAAGCTACTCGCGTGAGTTACACAATTTCCGCCTGCGGCTGGCGATAAGCGCCGGCTTCATG
CTGCTGCTCTTCCTGCTGCT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTLANSSRHEILMPAKSWFIMLSLIVALLLNLIPVTGTARTLQPDFVALVMLYWYLNEPQRVGIGMAFWMGLLMDLSNAS
TFGQHALGYSVMAFMALVFNRRMGIFEGYKQAPQIGLVLLSGQIVTLLAGLFAGSPFPGWNFFLGSIVGMLLWPLLSAIL
RVPQKPWSASDAR

Sequences:

>Translated_173_residues
MTLANSSRHEILMPAKSWFIMLSLIVALLLNLIPVTGTARTLQPDFVALVMLYWYLNEPQRVGIGMAFWMGLLMDLSNAS
TFGQHALGYSVMAFMALVFNRRMGIFEGYKQAPQIGLVLLSGQIVTLLAGLFAGSPFPGWNFFLGSIVGMLLWPLLSAIL
RVPQKPWSASDAR
>Mature_172_residues
TLANSSRHEILMPAKSWFIMLSLIVALLLNLIPVTGTARTLQPDFVALVMLYWYLNEPQRVGIGMAFWMGLLMDLSNAST
FGQHALGYSVMAFMALVFNRRMGIFEGYKQAPQIGLVLLSGQIVTLLAGLFAGSPFPGWNFFLGSIVGMLLWPLLSAILR
VPQKPWSASDAR

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=144, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 19123; Mature: 18992

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLANSSRHEILMPAKSWFIMLSLIVALLLNLIPVTGTARTLQPDFVALVMLYWYLNEPQ
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCH
RVGIGMAFWMGLLMDLSNASTFGQHALGYSVMAFMALVFNRRMGIFEGYKQAPQIGLVLL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEE
SGQIVTLLAGLFAGSPFPGWNFFLGSIVGMLLWPLLSAILRVPQKPWSASDAR
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TLANSSRHEILMPAKSWFIMLSLIVALLLNLIPVTGTARTLQPDFVALVMLYWYLNEPQ
CCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCH
RVGIGMAFWMGLLMDLSNASTFGQHALGYSVMAFMALVFNRRMGIFEGYKQAPQIGLVLL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEE
SGQIVTLLAGLFAGSPFPGWNFFLGSIVGMLLWPLLSAILRVPQKPWSASDAR
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]