Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 82701450

GI number: 82701450

Start: 340540

End: 341640

Strand: Reverse

Name: mrdB [H]

Synonym: Nmul_A0316

Alternate gene names: 82701450

Gene position: 341640-340540 (Counterclockwise)

Preceding gene: 82701451

Following gene: 82701449

Centisome position: 10.73

GC content: 56.58

Gene sequence:

>1101_bases
ATGGCTAGACTTCCACACGCAGGGCACTACTTTACGCGCTACATCGATGGTCTTCTGCTTTGTGGAATTCTCCTGCTCAT
GGCAACGGGACTTATCACACTTTTCAGCGCAACGGATGCCAATAGTGCGCGCGTCACGAGTCAGGCGATTAATATGCTGG
TCGCGCTCAGCGTGATGTGGCTGGTCGCCAACATTCCGTTGGAGCATATCATGCGGATCGCCTTACCGTTATACGTGGCG
GGCCTTTTCCTGCTGCTCTGCGTCGCGCTGTTCGGAGAGGTCAACAATGGCGCGAGGCGCTGGCTGAACCTGGGTGTAAC
CCGCATCCAGCCCTCCGAACTGATGAAGATTGCCGTACCGCTGATGATGGCCTGGTACTTCGACAAGCACGAGACAACCT
TGCGGCTGCGGGATTACGGTGTGGCCACCCTGCTGCTGCTGGCTCCGGTACTGTTGATCCTGCGCCAGCCTGATCTTGGA
ACCGCGCTGCTCATTGCCTCGAGCGGTTTTTATGTCCTGTTCTTTTCCGGGTTATCCTGGCGCATCATGGCGGCGGTGGC
GATTGCAGGGGGAGCAAGCCTTCCGCTGCTCTGGTCCATGATGCATGATTATCAGCGCAAGCGCGTCATGACGCTTCTTG
ACCCGACGCAGGACGCGCTTGGCGCCGGCTACCATACCATTCAATCCACTATTGCCATCGGCTCCGGGGGGGTGCTGGGC
AAGGGCTGGCAGCAAGGCACCCAAACCCATCTTGCGTTCCTCCCCGAGAGAAGCACTGATTTCATCTTCGCGGTATTCTC
CGAAGAATTCGGTCTGCTCGGCAATTTGCTGCTGCTGCTGTTGTATCTGGCTCTCATCGCCCGTGGGATGGTGATTGCCG
CCAACGCTTCCACCCAGTTTACCCGCCTCATCGCCGCTTCCATCACACTGACTTTCTTCACCTACATCTTCGTCAACATC
GGGATGGTCATCGGCATTCTGCCCGTGGTAGGGGTGCCTTTGCCCCTGATCAGCTATGGCGGCACATCAATGGTGACAAT
GTTGCTGGGATTTGGTATTTTGATGAGTATCCAGACTCATCCGAAGCTTGTTAAGACGTGA

Upstream 100 bases:

>100_bases
TATCTGCTGGGTAAACTGCCTAAGGAAGCAGCTGCACAGCCTGTCGATCAGGTGGACGAAGAGGAGGATGAGGAGCACCA
GCAGAACCGGGAGGACGGGC

Downstream 100 bases:

>100_bases
TACTTATGGATAAACTCCCTGCCTGCCTGTCCCTCATACCGTCAACTGCGCAGTCAAGAGGCCAGCCGGTTGCCAGGCGA
TGCGCCGCCTGGATGGCTGC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MARLPHAGHYFTRYIDGLLLCGILLLMATGLITLFSATDANSARVTSQAINMLVALSVMWLVANIPLEHIMRIALPLYVA
GLFLLLCVALFGEVNNGARRWLNLGVTRIQPSELMKIAVPLMMAWYFDKHETTLRLRDYGVATLLLLAPVLLILRQPDLG
TALLIASSGFYVLFFSGLSWRIMAAVAIAGGASLPLLWSMMHDYQRKRVMTLLDPTQDALGAGYHTIQSTIAIGSGGVLG
KGWQQGTQTHLAFLPERSTDFIFAVFSEEFGLLGNLLLLLLYLALIARGMVIAANASTQFTRLIAASITLTFFTYIFVNI
GMVIGILPVVGVPLPLISYGGTSMVTMLLGFGILMSIQTHPKLVKT

Sequences:

>Translated_366_residues
MARLPHAGHYFTRYIDGLLLCGILLLMATGLITLFSATDANSARVTSQAINMLVALSVMWLVANIPLEHIMRIALPLYVA
GLFLLLCVALFGEVNNGARRWLNLGVTRIQPSELMKIAVPLMMAWYFDKHETTLRLRDYGVATLLLLAPVLLILRQPDLG
TALLIASSGFYVLFFSGLSWRIMAAVAIAGGASLPLLWSMMHDYQRKRVMTLLDPTQDALGAGYHTIQSTIAIGSGGVLG
KGWQQGTQTHLAFLPERSTDFIFAVFSEEFGLLGNLLLLLLYLALIARGMVIAANASTQFTRLIAASITLTFFTYIFVNI
GMVIGILPVVGVPLPLISYGGTSMVTMLLGFGILMSIQTHPKLVKT
>Mature_365_residues
ARLPHAGHYFTRYIDGLLLCGILLLMATGLITLFSATDANSARVTSQAINMLVALSVMWLVANIPLEHIMRIALPLYVAG
LFLLLCVALFGEVNNGARRWLNLGVTRIQPSELMKIAVPLMMAWYFDKHETTLRLRDYGVATLLLLAPVLLILRQPDLGT
ALLIASSGFYVLFFSGLSWRIMAAVAIAGGASLPLLWSMMHDYQRKRVMTLLDPTQDALGAGYHTIQSTIAIGSGGVLGK
GWQQGTQTHLAFLPERSTDFIFAVFSEEFGLLGNLLLLLLYLALIARGMVIAANASTQFTRLIAASITLTFFTYIFVNIG
MVIGILPVVGVPLPLISYGGTSMVTMLLGFGILMSIQTHPKLVKT

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=336, Percent_Identity=51.4880952380952, Blast_Score=320, Evalue=9e-89,
Organism=Escherichia coli, GI1786277, Length=354, Percent_Identity=32.2033898305085, Blast_Score=157, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39888; Mature: 39757

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLPHAGHYFTRYIDGLLLCGILLLMATGLITLFSATDANSARVTSQAINMLVALSVMW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LVANIPLEHIMRIALPLYVAGLFLLLCVALFGEVNNGARRWLNLGVTRIQPSELMKIAVP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECHHHHHHHHHH
LMMAWYFDKHETTLRLRDYGVATLLLLAPVLLILRQPDLGTALLIASSGFYVLFFSGLSW
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCHH
RIMAAVAIAGGASLPLLWSMMHDYQRKRVMTLLDPTQDALGAGYHTIQSTIAIGSGGVLG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHEECCCCCCC
KGWQQGTQTHLAFLPERSTDFIFAVFSEEFGLLGNLLLLLLYLALIARGMVIAANASTQF
CCHHCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHH
TRLIAASITLTFFTYIFVNIGMVIGILPVVGVPLPLISYGGTSMVTMLLGFGILMSIQTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCC
PKLVKT
CCCCCC
>Mature Secondary Structure 
ARLPHAGHYFTRYIDGLLLCGILLLMATGLITLFSATDANSARVTSQAINMLVALSVMW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LVANIPLEHIMRIALPLYVAGLFLLLCVALFGEVNNGARRWLNLGVTRIQPSELMKIAVP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECHHHHHHHHHH
LMMAWYFDKHETTLRLRDYGVATLLLLAPVLLILRQPDLGTALLIASSGFYVLFFSGLSW
HHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCHH
RIMAAVAIAGGASLPLLWSMMHDYQRKRVMTLLDPTQDALGAGYHTIQSTIAIGSGGVLG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHEECCCCCCC
KGWQQGTQTHLAFLPERSTDFIFAVFSEEFGLLGNLLLLLLYLALIARGMVIAANASTQF
CCHHCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHH
TRLIAASITLTFFTYIFVNIGMVIGILPVVGVPLPLISYGGTSMVTMLLGFGILMSIQTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCC
PKLVKT
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]