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The map label for this gene is cysC [H]

Identifier: 82701433

GI number: 82701433

Start: 323093

End: 323770

Strand: Direct

Name: cysC [H]

Synonym: Nmul_A0299

Alternate gene names: 82701433

Gene position: 323093-323770 (Clockwise)

Preceding gene: 82701431

Following gene: 82701434

Centisome position: 10.15

GC content: 54.72

Gene sequence:

>678_bases
ATGAATACCAATACTGTATGGCACAACGCCACCATTACTCGGGCGCACCGGGAGAGGTTGAACGTGCACCGATCAGCGGT
CCTTTGGTTTACAGGGCTTTCCGGTTCCGGCAAATCGACGTTGGCTCATGCGGTGGAGGAAAAGCTTTACCAGCTGGGCT
GCCGCACGTTCGTACTTGACGGGGATAATGTGCGCCAGGGCTTATGCTCCGATCTGGGGTTTTCGGTGGAAGACCGTTCC
GAGAATATTCGCCGCATAAGCGAGGCAGCGAGGCTTCTGGTCGAGTCGGGCGTGATTGCCATGACAGCTTTTATTTCACC
TTTTCGGGCTGATCGGCAAAAGGCGCGCAGTATTTTTCCTCACGGGGATTTCATCGAGATTTTTTGCGAGGCCAGTCTCG
CAGTATGCGAGCAGCGCGATGTGAAGGGACTTTATAAACGGGCTCGGACGGGTGAGGTCAAGGAATTCACCGGGATATCG
TCGCCCTACGAGGCGCCTGCCACTCCCGAGCTGATCGTGCGGACAGGCGAGCTGGAGCTGGAGGATTGTGTTGCACAGGT
AATCGAATTCATGGAGCGGCGGGACATTTTCAAGAGAAAGCCTCAGTTGCGAGGAAGCGCCAGTCATCATAATGCGAAGG
ACCTTTCCCATTTGTCCATCGATGTTGTCAAGGAATGA

Upstream 100 bases:

>100_bases
CGCTCTGCTCTTCTGTATCTTGTACTTCGGTCCAGATATAAATCCGGATGGCTGTCGATATAATTCGGTTTATCCAAAAA
TCGGAATCTGAGATCGGAAC

Downstream 100 bases:

>100_bases
CAATCGCCCTGGATAAAGCGGTCGCCGCACTGCGGATAAAGGGTTTTTTCGTGCCTTTATGACAAAACAAAATTCAGAGG
ATGCGGTAAGAACATGAGGG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MNTNTVWHNATITRAHRERLNVHRSAVLWFTGLSGSGKSTLAHAVEEKLYQLGCRTFVLDGDNVRQGLCSDLGFSVEDRS
ENIRRISEAARLLVESGVIAMTAFISPFRADRQKARSIFPHGDFIEIFCEASLAVCEQRDVKGLYKRARTGEVKEFTGIS
SPYEAPATPELIVRTGELELEDCVAQVIEFMERRDIFKRKPQLRGSASHHNAKDLSHLSIDVVKE

Sequences:

>Translated_225_residues
MNTNTVWHNATITRAHRERLNVHRSAVLWFTGLSGSGKSTLAHAVEEKLYQLGCRTFVLDGDNVRQGLCSDLGFSVEDRS
ENIRRISEAARLLVESGVIAMTAFISPFRADRQKARSIFPHGDFIEIFCEASLAVCEQRDVKGLYKRARTGEVKEFTGIS
SPYEAPATPELIVRTGELELEDCVAQVIEFMERRDIFKRKPQLRGSASHHNAKDLSHLSIDVVKE
>Mature_225_residues
MNTNTVWHNATITRAHRERLNVHRSAVLWFTGLSGSGKSTLAHAVEEKLYQLGCRTFVLDGDNVRQGLCSDLGFSVEDRS
ENIRRISEAARLLVESGVIAMTAFISPFRADRQKARSIFPHGDFIEIFCEASLAVCEQRDVKGLYKRARTGEVKEFTGIS
SPYEAPATPELIVRTGELELEDCVAQVIEFMERRDIFKRKPQLRGSASHHNAKDLSHLSIDVVKE

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=200, Percent_Identity=48.5, Blast_Score=201, Evalue=3e-52,
Organism=Homo sapiens, GI62912492, Length=201, Percent_Identity=47.7611940298507, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI34447231, Length=201, Percent_Identity=47.7611940298507, Blast_Score=191, Evalue=3e-49,
Organism=Escherichia coli, GI1789107, Length=197, Percent_Identity=54.3147208121827, Blast_Score=224, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17542422, Length=205, Percent_Identity=45.3658536585366, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322852, Length=201, Percent_Identity=49.2537313432836, Blast_Score=198, Evalue=6e-52,
Organism=Drosophila melanogaster, GI116007838, Length=218, Percent_Identity=42.6605504587156, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667044, Length=218, Percent_Identity=42.6605504587156, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667032, Length=218, Percent_Identity=42.6605504587156, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667028, Length=218, Percent_Identity=42.6605504587156, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667036, Length=218, Percent_Identity=42.6605504587156, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24667040, Length=218, Percent_Identity=42.6605504587156, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 25302; Mature: 25302

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNTVWHNATITRAHRERLNVHRSAVLWFTGLSGSGKSTLAHAVEEKLYQLGCRTFVLD
CCCCEEEECCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEC
GDNVRQGLCSDLGFSVEDRSENIRRISEAARLLVESGVIAMTAFISPFRADRQKARSIFP
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
HGDFIEIFCEASLAVCEQRDVKGLYKRARTGEVKEFTGISSPYEAPATPELIVRTGELEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHEEEEECCCCH
EDCVAQVIEFMERRDIFKRKPQLRGSASHHNAKDLSHLSIDVVKE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCEEEEECC
>Mature Secondary Structure
MNTNTVWHNATITRAHRERLNVHRSAVLWFTGLSGSGKSTLAHAVEEKLYQLGCRTFVLD
CCCCEEEECCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEC
GDNVRQGLCSDLGFSVEDRSENIRRISEAARLLVESGVIAMTAFISPFRADRQKARSIFP
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
HGDFIEIFCEASLAVCEQRDVKGLYKRARTGEVKEFTGISSPYEAPATPELIVRTGELEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHEEEEECCCCH
EDCVAQVIEFMERRDIFKRKPQLRGSASHHNAKDLSHLSIDVVKE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]