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The map label for this gene is galE [H]

Identifier: 82701394

GI number: 82701394

Start: 281091

End: 282152

Strand: Direct

Name: galE [H]

Synonym: Nmul_A0260

Alternate gene names: 82701394

Gene position: 281091-282152 (Clockwise)

Preceding gene: 82701393

Following gene: 82701395

Centisome position: 8.83

GC content: 54.33

Gene sequence:

>1062_bases
ATGATCCTTGTTACCGGCGGCGCAGGCTATATAGGTTCCCACACCTGCCTGGAATTACTGAACGCAGGTCTTGATGTCAC
TGTATTCGACAATTTTTGTAATAGCCATCCTGAAGCATTAAGACGGGTTGAGCGCATCACCGGAAAGAAGCTGCGCGTTG
TGCAAGGCGACTGCCGTGACCGCTCCTCCGTGACCAAAGCCCTCCATGAGAGTCAGGCGACCGCGGTTATCCACTTCGCC
GGTCTTAAAGCGGTGGGAGAGTCGGTGAAGCAGCCCCTGGCTTACTACGATAATAATGTTGTTGGTACGCTCCGCTTGCT
GGAGGCGATGAATGAGTGTGGAGTGAAAACTCTGGTATTCAGTTCCTCTGCTACTGTTTACGGTGAGCCAAGGCGGCTAC
CGTTAACCGAAGATCATCCCCTCTCTGCCACGAATCCCTACGGACGGAGCAAACTGATGATCGAAGAAATTCTGCGCGAT
GTATATCGCAGTGATTCTTCCTGGCGCTGCGCCATCCTCAGGTATTTCAATCCTGTTGGAGCACATCCCAGCGGTCTGAT
CGGTGAAGATCCCAGAGGAACTCCTGATAATCTCATGCCCTTTGTGGCCCAGGTTGCCATTGGCCGTCGGGAGTATCTGA
ACGTGTGGGGCAATGACTATCCGACGCCGGATGGAACGGGCGTACGCGATTACATTCATGTCGTGGACTTGGCGTTAGGT
CATCTCAAAGCCCTCGAAGCTCTGGAGAATCCGGAAGTGCGCAATGCAGAGGCCGTTGACAGGCAAGGAGGATGCCTGAC
GGTAAACCTCGGGACCGGGACGGGCTATAGTGTGCTGGAAATGATAAGGGCTTTTGAAAAGGCGAGTGGGCAAAAGGTAT
CATACAGAATTGCTTCCCGCCGCCCGGGGGATATTGCCTCATGCTATGCTGAGCCCGGACTCGCATCCGATCTCCTCGGC
TGGCGGGCAAAGCGAGGGCTGGAAGAAATGTGCGTTGACACCTGGCACTGGCAGAACCAGAATCCCGAGGGATATGGAAG
CGAGAGTTCACATTTGGACTAG

Upstream 100 bases:

>100_bases
CTGATGACGATAAATCGTTTATGCTCTCTCGTCGATGCGTGATTATTGCGAAGGCGCCGAGCCATTATAATTTCTCTTTT
TGAAATGAAGCAGGACACTT

Downstream 100 bases:

>100_bases
AGTGAGTGGGTTCTGATTTCTTTGTCGCTATCACCGCTTTCCTGCCAGGGTTCCCGGTAAATCCGCTCGAGTAGCAACGA
TTCGTTCTTCGTAAAAACTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MILVTGGAGYIGSHTCLELLNAGLDVTVFDNFCNSHPEALRRVERITGKKLRVVQGDCRDRSSVTKALHESQATAVIHFA
GLKAVGESVKQPLAYYDNNVVGTLRLLEAMNECGVKTLVFSSSATVYGEPRRLPLTEDHPLSATNPYGRSKLMIEEILRD
VYRSDSSWRCAILRYFNPVGAHPSGLIGEDPRGTPDNLMPFVAQVAIGRREYLNVWGNDYPTPDGTGVRDYIHVVDLALG
HLKALEALENPEVRNAEAVDRQGGCLTVNLGTGTGYSVLEMIRAFEKASGQKVSYRIASRRPGDIASCYAEPGLASDLLG
WRAKRGLEEMCVDTWHWQNQNPEGYGSESSHLD

Sequences:

>Translated_353_residues
MILVTGGAGYIGSHTCLELLNAGLDVTVFDNFCNSHPEALRRVERITGKKLRVVQGDCRDRSSVTKALHESQATAVIHFA
GLKAVGESVKQPLAYYDNNVVGTLRLLEAMNECGVKTLVFSSSATVYGEPRRLPLTEDHPLSATNPYGRSKLMIEEILRD
VYRSDSSWRCAILRYFNPVGAHPSGLIGEDPRGTPDNLMPFVAQVAIGRREYLNVWGNDYPTPDGTGVRDYIHVVDLALG
HLKALEALENPEVRNAEAVDRQGGCLTVNLGTGTGYSVLEMIRAFEKASGQKVSYRIASRRPGDIASCYAEPGLASDLLG
WRAKRGLEEMCVDTWHWQNQNPEGYGSESSHLD
>Mature_353_residues
MILVTGGAGYIGSHTCLELLNAGLDVTVFDNFCNSHPEALRRVERITGKKLRVVQGDCRDRSSVTKALHESQATAVIHFA
GLKAVGESVKQPLAYYDNNVVGTLRLLEAMNECGVKTLVFSSSATVYGEPRRLPLTEDHPLSATNPYGRSKLMIEEILRD
VYRSDSSWRCAILRYFNPVGAHPSGLIGEDPRGTPDNLMPFVAQVAIGRREYLNVWGNDYPTPDGTGVRDYIHVVDLALG
HLKALEALENPEVRNAEAVDRQGGCLTVNLGTGTGYSVLEMIRAFEKASGQKVSYRIASRRPGDIASCYAEPGLASDLLG
WRAKRGLEEMCVDTWHWQNQNPEGYGSESSHLD

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=355, Percent_Identity=58.0281690140845, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI56118217, Length=355, Percent_Identity=58.0281690140845, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI189083684, Length=355, Percent_Identity=58.0281690140845, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI7657641, Length=355, Percent_Identity=24.2253521126761, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI42516563, Length=342, Percent_Identity=26.0233918128655, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786974, Length=345, Percent_Identity=54.2028985507246, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI48994969, Length=255, Percent_Identity=26.2745098039216, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=24.8618784530387, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788366, Length=347, Percent_Identity=25.6484149855908, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=354, Percent_Identity=51.1299435028249, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71982038, Length=356, Percent_Identity=51.4044943820225, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17568069, Length=246, Percent_Identity=28.8617886178862, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=350, Percent_Identity=50.5714285714286, Blast_Score=353, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6321437, Length=376, Percent_Identity=23.6702127659574, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19923002, Length=354, Percent_Identity=57.0621468926554, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38765; Mature: 38765

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGAGYIGSHTCLELLNAGLDVTVFDNFCNSHPEALRRVERITGKKLRVVQGDCRD
CEEEECCCCCCCHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHCCCEEEEEECCCCC
RSSVTKALHESQATAVIHFAGLKAVGESVKQPLAYYDNNVVGTLRLLEAMNECGVKTLVF
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEE
SSSATVYGEPRRLPLTEDHPLSATNPYGRSKLMIEEILRDVYRSDSSWRCAILRYFNPVG
ECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHEECCCCCC
AHPSGLIGEDPRGTPDNLMPFVAQVAIGRREYLNVWGNDYPTPDGTGVRDYIHVVDLALG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
HLKALEALENPEVRNAEAVDRQGGCLTVNLGTGTGYSVLEMIRAFEKASGQKVSYRIASR
HHHHHHHHCCCCCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
RPGDIASCYAEPGLASDLLGWRAKRGLEEMCVDTWHWQNQNPEGYGSESSHLD
CCCCHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MILVTGGAGYIGSHTCLELLNAGLDVTVFDNFCNSHPEALRRVERITGKKLRVVQGDCRD
CEEEECCCCCCCHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHCCCEEEEEECCCCC
RSSVTKALHESQATAVIHFAGLKAVGESVKQPLAYYDNNVVGTLRLLEAMNECGVKTLVF
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEE
SSSATVYGEPRRLPLTEDHPLSATNPYGRSKLMIEEILRDVYRSDSSWRCAILRYFNPVG
ECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHEECCCCCC
AHPSGLIGEDPRGTPDNLMPFVAQVAIGRREYLNVWGNDYPTPDGTGVRDYIHVVDLALG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
HLKALEALENPEVRNAEAVDRQGGCLTVNLGTGTGYSVLEMIRAFEKASGQKVSYRIASR
HHHHHHHHCCCCCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
RPGDIASCYAEPGLASDLLGWRAKRGLEEMCVDTWHWQNQNPEGYGSESSHLD
CCCCHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]