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The map label for this gene is wecB [H]

Identifier: 82701393

GI number: 82701393

Start: 279672

End: 280787

Strand: Direct

Name: wecB [H]

Synonym: Nmul_A0259

Alternate gene names: 82701393

Gene position: 279672-280787 (Clockwise)

Preceding gene: 82701392

Following gene: 82701394

Centisome position: 8.78

GC content: 52.15

Gene sequence:

>1116_bases
ATGAAAAAAATTTATCTTGTTGCCGGAGCTCGTCCCAATTTCATGAAAATTGCGCCGGTCGTGCGCGCTTTGCAGACTCG
CAAGTGTCTGGAATTTAAGATTATTCATACTGGCCAGCATTACGACAGGGAGATGAATGACGTTTTCTTTGAAGAACTCG
GCATCCCCCAGCCGGATGTTTTCATGGCTGCGGGTGGCGGAACTCATGCGCAACAGACCGCAAGGATCATGATGGCATTC
GAAGAGTTTTGTGAGGCTGATCCCCCGGATGCTGTGCTGGTGGTAGGGGATGTGAACTCGACACTGGCCTGTTCCATTGT
AGCCAAAAAGTTGCATATACCCGTGGCTCACGTGGAGGCAGGTTTAAGGAGCGGCGATATCACGATGCCGGAGGAAGTCA
ACCGTATCGTTACCGATAGCATTTCCGACTGGTTTTTCGTGACTGAGCCCAGTGGAATAGATCATTTGAAGCGGGAAGGA
AAGCCGGATTCCGCCATTCATTACGTTGGCCACGTGATGATCGATAATTTACTGTACCAGCTCGAAAAGCTGGAGGACCA
TGATATTTCAAGTCTTGAAACAAGCCCCTTCAAGGCGAAGCTTGCGATCAACGGAAGTCGTTATGGAGTCGTGACTCTCC
ACCGGCCGAGCAATGTGGATAACGTCGAGATGATAACCCGGCTGTGTGGTGCGCTGCGGGAGATTGCCGTGGAATTGCCC
CTGATTTTTCCGGTTCATCCCCGGACGCGGGGGAATCTGGAAAAGTTTGGCATTGAGCTGGGGCCGAACATCACGCTGCT
GGGACCGCAGGCATACATGCCTTTTCTTAATTTATGGAAAGACGCCGCCGTGGTGCTGACCGACAGTGGAGGATTACAGG
AAGAAACCACTGCTCTCGGGGTGCCTTGCGTTACTCTTCGCGATAATACCGAACGTCCCATCACTGTGGAAGAGGGGTCC
AACGTTTTGGCTGGTACCGATCCGGTCCGCATCATTGGCGAAGTACGAAAGATATTGCATGGAGAAGGCAAGCGCAGCCA
ACGGCCCCATCTATGGGATGGAAAAGCGGCTGAACGGATAGTGGATGTGCTGGTGAGGGAAGTAAGTCAGGCGTAA

Upstream 100 bases:

>100_bases
AGCCCGACATTTATTTGATGATGCTGGTCGGCGGGGCAGCCATCGGTTTCTTCACGTATAAGCGTCGAACGACCTTGCTA
ACAGAGAATCCTGTGCCAGC

Downstream 100 bases:

>100_bases
ACACCACGCTGTGGCTCAGCACGGCTAATAACGGTTACTGGCGGTGTCATCAGCCCAGAGTAAATCTGGAGGAACGTTCG
CGATAAGATGTGGCAATTGA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKKIYLVAGARPNFMKIAPVVRALQTRKCLEFKIIHTGQHYDREMNDVFFEELGIPQPDVFMAAGGGTHAQQTARIMMAF
EEFCEADPPDAVLVVGDVNSTLACSIVAKKLHIPVAHVEAGLRSGDITMPEEVNRIVTDSISDWFFVTEPSGIDHLKREG
KPDSAIHYVGHVMIDNLLYQLEKLEDHDISSLETSPFKAKLAINGSRYGVVTLHRPSNVDNVEMITRLCGALREIAVELP
LIFPVHPRTRGNLEKFGIELGPNITLLGPQAYMPFLNLWKDAAVVLTDSGGLQEETTALGVPCVTLRDNTERPITVEEGS
NVLAGTDPVRIIGEVRKILHGEGKRSQRPHLWDGKAAERIVDVLVREVSQA

Sequences:

>Translated_371_residues
MKKIYLVAGARPNFMKIAPVVRALQTRKCLEFKIIHTGQHYDREMNDVFFEELGIPQPDVFMAAGGGTHAQQTARIMMAF
EEFCEADPPDAVLVVGDVNSTLACSIVAKKLHIPVAHVEAGLRSGDITMPEEVNRIVTDSISDWFFVTEPSGIDHLKREG
KPDSAIHYVGHVMIDNLLYQLEKLEDHDISSLETSPFKAKLAINGSRYGVVTLHRPSNVDNVEMITRLCGALREIAVELP
LIFPVHPRTRGNLEKFGIELGPNITLLGPQAYMPFLNLWKDAAVVLTDSGGLQEETTALGVPCVTLRDNTERPITVEEGS
NVLAGTDPVRIIGEVRKILHGEGKRSQRPHLWDGKAAERIVDVLVREVSQA
>Mature_371_residues
MKKIYLVAGARPNFMKIAPVVRALQTRKCLEFKIIHTGQHYDREMNDVFFEELGIPQPDVFMAAGGGTHAQQTARIMMAF
EEFCEADPPDAVLVVGDVNSTLACSIVAKKLHIPVAHVEAGLRSGDITMPEEVNRIVTDSISDWFFVTEPSGIDHLKREG
KPDSAIHYVGHVMIDNLLYQLEKLEDHDISSLETSPFKAKLAINGSRYGVVTLHRPSNVDNVEMITRLCGALREIAVELP
LIFPVHPRTRGNLEKFGIELGPNITLLGPQAYMPFLNLWKDAAVVLTDSGGLQEETTALGVPCVTLRDNTERPITVEEGS
NVLAGTDPVRIIGEVRKILHGEGKRSQRPHLWDGKAAERIVDVLVREVSQA

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=383, Percent_Identity=36.0313315926893, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41020; Mature: 41020

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIYLVAGARPNFMKIAPVVRALQTRKCLEFKIIHTGQHYDREMNDVFFEELGIPQPDV
CCEEEEEECCCCCHHHHHHHHHHHHHHHCEEEEEEECCCHHCCHHHHHHHHHHCCCCCCE
FMAAGGGTHAQQTARIMMAFEEFCEADPPDAVLVVGDVNSTLACSIVAKKLHIPVAHVEA
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHC
GLRSGDITMPEEVNRIVTDSISDWFFVTEPSGIDHLKREGKPDSAIHYVGHVMIDNLLYQ
CCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LEKLEDHDISSLETSPFKAKLAINGSRYGVVTLHRPSNVDNVEMITRLCGALREIAVELP
HHHCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
LIFPVHPRTRGNLEKFGIELGPNITLLGPQAYMPFLNLWKDAAVVLTDSGGLQEETTALG
EEEECCCCCCCCHHHCCEEECCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHCC
VPCVTLRDNTERPITVEEGSNVLAGTDPVRIIGEVRKILHGEGKRSQRPHLWDGKAAERI
CCEEEECCCCCCCEEEECCCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VDVLVREVSQA
HHHHHHHHHCC
>Mature Secondary Structure
MKKIYLVAGARPNFMKIAPVVRALQTRKCLEFKIIHTGQHYDREMNDVFFEELGIPQPDV
CCEEEEEECCCCCHHHHHHHHHHHHHHHCEEEEEEECCCHHCCHHHHHHHHHHCCCCCCE
FMAAGGGTHAQQTARIMMAFEEFCEADPPDAVLVVGDVNSTLACSIVAKKLHIPVAHVEA
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHC
GLRSGDITMPEEVNRIVTDSISDWFFVTEPSGIDHLKREGKPDSAIHYVGHVMIDNLLYQ
CCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LEKLEDHDISSLETSPFKAKLAINGSRYGVVTLHRPSNVDNVEMITRLCGALREIAVELP
HHHCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
LIFPVHPRTRGNLEKFGIELGPNITLLGPQAYMPFLNLWKDAAVVLTDSGGLQEETTALG
EEEECCCCCCCCHHHCCEEECCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHCC
VPCVTLRDNTERPITVEEGSNVLAGTDPVRIIGEVRKILHGEGKRSQRPHLWDGKAAERI
CCEEEECCCCCCCEEEECCCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VDVLVREVSQA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA