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The map label for this gene is metX

Identifier: 82701355

GI number: 82701355

Start: 235602

End: 236735

Strand: Direct

Name: metX

Synonym: Nmul_A0221

Alternate gene names: 82701355

Gene position: 235602-236735 (Clockwise)

Preceding gene: 82701354

Following gene: 82701356

Centisome position: 7.4

GC content: 54.14

Gene sequence:

>1134_bases
ATGCTCATGCAAGATTCGAATTCATTCAGTACTGTTACTCCACAGGTGGCGCGTTTTGACACGCCTTTGCATTTGAAAAG
CGGCGCGGTGCTCGACAGCTACGAGCTGGTGTACGAAACATACGGGGAGCTCAACGCGGCGCGGTCGAACGCCGTACTGG
TATGCCACGCCCTTTCAGGGAATCATCATCTCGCAGGCCTTTACGACGATAACCCCAAGAGTGCCGGCTGGTGGAACAAC
ATGATCGGGCCGGGCAAATCGATCGATACCCAGAAATTTTTCTTAATCGGGGTAAACAACCTGGGCGGTTGTCATGGATC
CACCGGACCGGCGAGTATTGATGTCAGGACTGGAAAGTGTTACGGCCCGAATTTTCCGGTTGTGACAGTGGAAGACTGGG
TTCAGACACAAGTCCGCCTTGCCGATTATCTGGGTATCGATCAGTTTGCCGCCGTGGCTGGCGGTAGTCTTGGCGGAATG
CAGGCTTTGCAGTGGACACTTGATTTTCCCGAGAGGGTGCGCCACGCGCTGGTTATCGCCGCGGCTGCAAAGTTGACTGC
GCAGAACATCGCATTCAACGATGTGGCACGCCAAGCTATCATTACCGATCCTGATTTCCATGGCGGCGACTATTATTCAC
ACGGTGTCATTCCGCGGAGAGGATTACGCCTGGCGCGCATGCTGGGACATATCACCTACCTCTCGGACGACTCGATGGCG
GCTAAATTCGGCCGGGAACTGCGGAATGGAGCGCTTGCCTTCGGTTACGACGTGGAGTTCGAAATAGAATCGTATCTTCG
TTATCAGGGAGATAAATTCGCTAGCCAGTTCGATGCGAACACGTATCTGCTGATGACAAAGGCATTGGACTATTTTGATC
CTGCCTTTCCGCACAACAACGACCTCAGCGCCGCATTCCGATTCGCCAGGGCTAATTTCCTGGTGCTGTCGTTTACTACC
GACTGGCGTTTTTCCCCGGAGCGCTCGCGCGCCATCGTAAGGGCGCTGCTGGACAACGAACTGAACGTCAGTTATGCCGA
AATTACATCCAGTCATGGCCACGACTCGTTCCTCATGGAGGATCGGCATTATCACAGGCTGGTGCGGGCTTACATGGATA
ACGTGGTCGTATGA

Upstream 100 bases:

>100_bases
TGAAAGGGGAATTCCTGCGCCTGCGTAAAACCGGTTTTAATTTTCTGGAGACCGGGCTCGGGAACGAACAAATAGTGACG
TCAGCCTCCTGACCTTTTTT

Downstream 100 bases:

>100_bases
AGAAATCCCTTGGCATGAATTCATCGCTTAATGCTGCCCGGCCCGATTTTGCCCTCATTGCAGCATGGGTCAAACCGGGG
GCCAAGGTACTCGATCTGGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLMQDSNSFSTVTPQVARFDTPLHLKSGAVLDSYELVYETYGELNAARSNAVLVCHALSGNHHLAGLYDDNPKSAGWWNN
MIGPGKSIDTQKFFLIGVNNLGGCHGSTGPASIDVRTGKCYGPNFPVVTVEDWVQTQVRLADYLGIDQFAAVAGGSLGGM
QALQWTLDFPERVRHALVIAAAAKLTAQNIAFNDVARQAIITDPDFHGGDYYSHGVIPRRGLRLARMLGHITYLSDDSMA
AKFGRELRNGALAFGYDVEFEIESYLRYQGDKFASQFDANTYLLMTKALDYFDPAFPHNNDLSAAFRFARANFLVLSFTT
DWRFSPERSRAIVRALLDNELNVSYAEITSSHGHDSFLMEDRHYHRLVRAYMDNVVV

Sequences:

>Translated_377_residues
MLMQDSNSFSTVTPQVARFDTPLHLKSGAVLDSYELVYETYGELNAARSNAVLVCHALSGNHHLAGLYDDNPKSAGWWNN
MIGPGKSIDTQKFFLIGVNNLGGCHGSTGPASIDVRTGKCYGPNFPVVTVEDWVQTQVRLADYLGIDQFAAVAGGSLGGM
QALQWTLDFPERVRHALVIAAAAKLTAQNIAFNDVARQAIITDPDFHGGDYYSHGVIPRRGLRLARMLGHITYLSDDSMA
AKFGRELRNGALAFGYDVEFEIESYLRYQGDKFASQFDANTYLLMTKALDYFDPAFPHNNDLSAAFRFARANFLVLSFTT
DWRFSPERSRAIVRALLDNELNVSYAEITSSHGHDSFLMEDRHYHRLVRAYMDNVVV
>Mature_377_residues
MLMQDSNSFSTVTPQVARFDTPLHLKSGAVLDSYELVYETYGELNAARSNAVLVCHALSGNHHLAGLYDDNPKSAGWWNN
MIGPGKSIDTQKFFLIGVNNLGGCHGSTGPASIDVRTGKCYGPNFPVVTVEDWVQTQVRLADYLGIDQFAAVAGGSLGGM
QALQWTLDFPERVRHALVIAAAAKLTAQNIAFNDVARQAIITDPDFHGGDYYSHGVIPRRGLRLARMLGHITYLSDDSMA
AKFGRELRNGALAFGYDVEFEIESYLRYQGDKFASQFDANTYLLMTKALDYFDPAFPHNNDLSAAFRFARANFLVLSFTT
DWRFSPERSRAIVRALLDNELNVSYAEITSSHGHDSFLMEDRHYHRLVRAYMDNVVV

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=224, Percent_Identity=36.1607142857143, Blast_Score=151, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_NITMU (Q2YCJ2)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_410921.1
- STRING:   Q2YCJ2
- GeneID:   3784598
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0221
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q2YCJ2
- ProtClustDB:   PRK00175
- BioCyc:   NMUL323848:NMUL_A0221-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41944; Mature: 41944

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: ACT_SITE 156-156 ACT_SITE 354-354

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMQDSNSFSTVTPQVARFDTPLHLKSGAVLDSYELVYETYGELNAARSNAVLVCHALSG
CCCCCCCCCCCCCCHHHHCCCCEEECCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEECC
NHHLAGLYDDNPKSAGWWNNMIGPGKSIDTQKFFLIGVNNLGGCHGSTGPASIDVRTGKC
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCE
YGPNFPVVTVEDWVQTQVRLADYLGIDQFAAVAGGSLGGMQALQWTLDFPERVRHALVIA
ECCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHH
AAAKLTAQNIAFNDVARQAIITDPDFHGGDYYSHGVIPRRGLRLARMLGHITYLSDDSMA
HHHHHHHHCCHHHHHHHHHEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHEEECCCHHH
AKFGRELRNGALAFGYDVEFEIESYLRYQGDKFASQFDANTYLLMTKALDYFDPAFPHNN
HHHHHHHHCCCEEEEEEEEEEHHHHHHHCCHHHHHHHCCCEEEEEEHHHHHCCCCCCCCC
DLSAAFRFARANFLVLSFTTDWRFSPERSRAIVRALLDNELNVSYAEITSSHGHDSFLME
CHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEC
DRHYHRLVRAYMDNVVV
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLMQDSNSFSTVTPQVARFDTPLHLKSGAVLDSYELVYETYGELNAARSNAVLVCHALSG
CCCCCCCCCCCCCCHHHHCCCCEEECCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEECC
NHHLAGLYDDNPKSAGWWNNMIGPGKSIDTQKFFLIGVNNLGGCHGSTGPASIDVRTGKC
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCE
YGPNFPVVTVEDWVQTQVRLADYLGIDQFAAVAGGSLGGMQALQWTLDFPERVRHALVIA
ECCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHH
AAAKLTAQNIAFNDVARQAIITDPDFHGGDYYSHGVIPRRGLRLARMLGHITYLSDDSMA
HHHHHHHHCCHHHHHHHHHEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHEEECCCHHH
AKFGRELRNGALAFGYDVEFEIESYLRYQGDKFASQFDANTYLLMTKALDYFDPAFPHNN
HHHHHHHHCCCEEEEEEEEEEHHHHHHHCCHHHHHHHCCCEEEEEEHHHHHCCCCCCCCC
DLSAAFRFARANFLVLSFTTDWRFSPERSRAIVRALLDNELNVSYAEITSSHGHDSFLME
CHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEC
DRHYHRLVRAYMDNVVV
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA