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The map label for this gene is guaD [H]

Identifier: 82701279

GI number: 82701279

Start: 152774

End: 153217

Strand: Reverse

Name: guaD [H]

Synonym: Nmul_A0144

Alternate gene names: 82701279

Gene position: 153217-152774 (Counterclockwise)

Preceding gene: 82701280

Following gene: 82701278

Centisome position: 4.81

GC content: 58.78

Gene sequence:

>444_bases
ATGTCTCAACATGAAACATTTCTGCGGGAAGCAGTGCGTCTCGCCAAAAACAACCGTGAACGGGGTAGCCGGCCCTTTGC
CGCAGTCCTCGTTGTCGAGGGACAAGCCGTTTCCACCGGCGTCAACGACGTGGTGCAGAGCAATGATCCTACCACGCATG
CAGAAATGGAGGCAGTGCGCGCTGCCAGCCGGAAGCTCGGTCGTCCTGATCTGAGAGGCAGCATAGTTTACGCCAGCGGC
CACCCCTGCCCCATGTGCCTGGCAGCCATGGTGATAGCAGGAGTGGATGCGGTCTATTACGCTTTCGACAACGATGACGC
GGAACCCTATGGTTTTTCGAGCAAGGCGACCTATCAGAAGCTGAGCCTGCCACTAAAGCCTCCACCCCTGCCGCTCATTC
GACTCGATCTCGGCCTGTCTGCCGCAGAACTGTACGGCGCCTAG

Upstream 100 bases:

>100_bases
TCTTTTTTAAGGGGAAGGGATTCCAGGAGCTTGCCGTAATCATATCGGTGCGACAGCTTGGCACAAGCGCTACAGACAGG
TAAGTCAAACAGGAAGCCAG

Downstream 100 bases:

>100_bases
CTTTGCAACCTGAGAATGGGAGCAGGAAAAGAATAAGGAGGTAAGACGTGGCCGTGCGTTCCGCGGCTTTTTTGGGGGGT
TGGCAAGAGTGTCGAAAAGT

Product: cytidine/deoxycytidylate deaminase zinc-binding subunit

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSQHETFLREAVRLAKNNRERGSRPFAAVLVVEGQAVSTGVNDVVQSNDPTTHAEMEAVRAASRKLGRPDLRGSIVYASG
HPCPMCLAAMVIAGVDAVYYAFDNDDAEPYGFSSKATYQKLSLPLKPPPLPLIRLDLGLSAAELYGA

Sequences:

>Translated_147_residues
MSQHETFLREAVRLAKNNRERGSRPFAAVLVVEGQAVSTGVNDVVQSNDPTTHAEMEAVRAASRKLGRPDLRGSIVYASG
HPCPMCLAAMVIAGVDAVYYAFDNDDAEPYGFSSKATYQKLSLPLKPPPLPLIRLDLGLSAAELYGA
>Mature_146_residues
SQHETFLREAVRLAKNNRERGSRPFAAVLVVEGQAVSTGVNDVVQSNDPTTHAEMEAVRAASRKLGRPDLRGSIVYASGH
PCPMCLAAMVIAGVDAVYYAFDNDDAEPYGFSSKATYQKLSLPLKPPPLPLIRLDLGLSAAELYGA

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17554608, Length=119, Percent_Identity=37.8151260504202, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17555996, Length=124, Percent_Identity=41.1290322580645, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 15817; Mature: 15686

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQHETFLREAVRLAKNNRERGSRPFAAVLVVEGQAVSTGVNDVVQSNDPTTHAEMEAVR
CCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHH
AASRKLGRPDLRGSIVYASGHPCPMCLAAMVIAGVDAVYYAFDNDDAEPYGFSSKATYQK
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHH
LSLPLKPPPLPLIRLDLGLSAAELYGA
HCCCCCCCCCCEEEEECCCCHHHHCCC
>Mature Secondary Structure 
SQHETFLREAVRLAKNNRERGSRPFAAVLVVEGQAVSTGVNDVVQSNDPTTHAEMEAVR
CHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHH
AASRKLGRPDLRGSIVYASGHPCPMCLAAMVIAGVDAVYYAFDNDDAEPYGFSSKATYQK
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHH
LSLPLKPPPLPLIRLDLGLSAAELYGA
HCCCCCCCCCCEEEEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]