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The map label for this gene is pac [H]

Identifier: 82546688

GI number: 82546688

Start: 4445504

End: 4446850

Strand: Direct

Name: pac [H]

Synonym: SBO_4393

Alternate gene names: 82546688

Gene position: 4445504-4446850 (Clockwise)

Preceding gene: 82546687

Following gene: 82546692

Centisome position: 98.36

GC content: 47.51

Gene sequence:

>1347_bases
ATGATCGTGAACTGTGTTACTGCTTCCCTGATGTATTATTGGAGCTTACCTGCACTGGCTGAGCAGTCGTCAAGTGAGAT
AAAGATTGTTCGCGATGAATACGGCATGCCGCATATTTATGCCAATGATACATGGCACCTATTTTATGGCTATGGCTATG
TAGTAGCACAAGATCGCCTTTTTCAGATGGAAATGGCACGTCGCAGTACTCAAGGGACTGTCGCGGAAGTGCTTGGCAAA
GATTTTGTGAAATTTGATAAAGATATCCGTCGTAACTACTGGCCGGATGCTATCCGGGCGCAAATTGATGCCCTTTCCCC
AGAGGATATGTCCATTCTGCAAGGCTACGCTGATGGAATGAATGCCTGGATTGATAAGGTAAATACCAATCCAGAGACGC
TCTTACCAAAACAGTTTAATACATTTGGCTTTACTCCTAAGCGCTGGGAACCGTTTGATGTCGCGATGATATTTGTGGGC
ACCATGGCAAACCGCTTCTCTGATAGCACTAGCGAAATTGATAATCTGGCACTGCTAACGGCTTTAAAAGATAAATATGG
TGTATCACAAGGCATGGCGGTATTTAATCAGTTGAAATGGCTGGTAAACCCATCAGCGCCAACCACTATTGCCGTACAAG
AGAGTAGCTACCCACTTAAATTTAATCAGCAAAACTCGCAAACAGCAGCTCTGTTGCCACGCTACGATTTACCTGCACCA
ATGCTTGACCGACCAGCAAAAGGGGCGGATGGCGCACTGCTGGCGTTAACAGCAGGGAAGAACCGGGAAACTATTGCTGC
ACAATTTGCACAGGGTGGTGCCAATGGTCTGGCGGGGTATCCAACGACCAGCAATATGTGGGTGATCGGCAAAAGCAAAG
CCCAGGATGCGAAAGCAATCATGGTAAATGGTCCGCAGTTTGGCTGGTATGCGCCTGCGTATACTTATGGTATTGGTCTG
CACGGTGCTGGTTATGATGTCACTGGCAATACACCATTTGCCTATCCTGGGCTGGTTTTTGGTCATAATGGTGTGATTTC
CTGGGGATCAACGGCAGGTTTCGGCGATGATGTCGATATTTTTGCTGAACGGCTGTCGGCAGAGAAACCAGGCTACTACT
TACATAATTGTAAGTGGGTGAAAATGTTAAGCCGTGAGGAAACCATTACGGTGAAAAATGGTCAGGCAGAGACCTTTACT
GTCTGGCGTACGGTGCATGGCAACATTCTCCAAACTGACCAGACGACACAAACGGCTTACGCTAAATCCCGCGCATGGGA
TGGTAAAGAGGTGGCGTCTTTGCTGGCCTGGACTCATCAGATGAAGGCCAAAAATTGGCAGGAGTAG

Upstream 100 bases:

>100_bases
TCGCTCGCCACGGGAATATCTGCGGCAGCGGGCTTGTAATGGGTTAAGTGATAACAGATGTCTGGAAATATAGGGGCAAA
TCCAGAAAAATAGAAATCGT

Downstream 100 bases:

>100_bases
CGAAACAAGCACTGACCATCAACTGGTACTATGCTGATGTAAACGGCAATATTGGTTATGTTCATACTGGTGCTTATCCA
GATCGTCAATCAGGCCATGA

Product: penicillin G acylase

Products: NA

Alternate protein names: Penicillin G amidase; Penicillin G amidohydrolase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MIVNCVTASLMYYWSLPALAEQSSSEIKIVRDEYGMPHIYANDTWHLFYGYGYVVAQDRLFQMEMARRSTQGTVAEVLGK
DFVKFDKDIRRNYWPDAIRAQIDALSPEDMSILQGYADGMNAWIDKVNTNPETLLPKQFNTFGFTPKRWEPFDVAMIFVG
TMANRFSDSTSEIDNLALLTALKDKYGVSQGMAVFNQLKWLVNPSAPTTIAVQESSYPLKFNQQNSQTAALLPRYDLPAP
MLDRPAKGADGALLALTAGKNRETIAAQFAQGGANGLAGYPTTSNMWVIGKSKAQDAKAIMVNGPQFGWYAPAYTYGIGL
HGAGYDVTGNTPFAYPGLVFGHNGVISWGSTAGFGDDVDIFAERLSAEKPGYYLHNCKWVKMLSREETITVKNGQAETFT
VWRTVHGNILQTDQTTQTAYAKSRAWDGKEVASLLAWTHQMKAKNWQE

Sequences:

>Translated_448_residues
MIVNCVTASLMYYWSLPALAEQSSSEIKIVRDEYGMPHIYANDTWHLFYGYGYVVAQDRLFQMEMARRSTQGTVAEVLGK
DFVKFDKDIRRNYWPDAIRAQIDALSPEDMSILQGYADGMNAWIDKVNTNPETLLPKQFNTFGFTPKRWEPFDVAMIFVG
TMANRFSDSTSEIDNLALLTALKDKYGVSQGMAVFNQLKWLVNPSAPTTIAVQESSYPLKFNQQNSQTAALLPRYDLPAP
MLDRPAKGADGALLALTAGKNRETIAAQFAQGGANGLAGYPTTSNMWVIGKSKAQDAKAIMVNGPQFGWYAPAYTYGIGL
HGAGYDVTGNTPFAYPGLVFGHNGVISWGSTAGFGDDVDIFAERLSAEKPGYYLHNCKWVKMLSREETITVKNGQAETFT
VWRTVHGNILQTDQTTQTAYAKSRAWDGKEVASLLAWTHQMKAKNWQE
>Mature_448_residues
MIVNCVTASLMYYWSLPALAEQSSSEIKIVRDEYGMPHIYANDTWHLFYGYGYVVAQDRLFQMEMARRSTQGTVAEVLGK
DFVKFDKDIRRNYWPDAIRAQIDALSPEDMSILQGYADGMNAWIDKVNTNPETLLPKQFNTFGFTPKRWEPFDVAMIFVG
TMANRFSDSTSEIDNLALLTALKDKYGVSQGMAVFNQLKWLVNPSAPTTIAVQESSYPLKFNQQNSQTAALLPRYDLPAP
MLDRPAKGADGALLALTAGKNRETIAAQFAQGGANGLAGYPTTSNMWVIGKSKAQDAKAIMVNGPQFGWYAPAYTYGIGL
HGAGYDVTGNTPFAYPGLVFGHNGVISWGSTAGFGDDVDIFAERLSAEKPGYYLHNCKWVKMLSREETITVKNGQAETFT
VWRTVHGNILQTDQTTQTAYAKSRAWDGKEVASLLAWTHQMKAKNWQE

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 49807; Mature: 49807

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVNCVTASLMYYWSLPALAEQSSSEIKIVRDEYGMPHIYANDTWHLFYGYGYVVAQDRL
CEEHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCCCEEEECCEEEEEEEEEEEEEHHHH
FQMEMARRSTQGTVAEVLGKDFVKFDKDIRRNYWPDAIRAQIDALSPEDMSILQGYADGM
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
NAWIDKVNTNPETLLPKQFNTFGFTPKRWEPFDVAMIFVGTMANRFSDSTSEIDNLALLT
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALKDKYGVSQGMAVFNQLKWLVNPSAPTTIAVQESSYPLKFNQQNSQTAALLPRYDLPAP
HHHHHHCHHHHHHHHHHHHHEECCCCCCEEEEECCCCCEEECCCCCCEEEECCCCCCCCC
MLDRPAKGADGALLALTAGKNRETIAAQFAQGGANGLAGYPTTSNMWVIGKSKAQDAKAI
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEE
MVNGPQFGWYAPAYTYGIGLHGAGYDVTGNTPFAYPGLVFGHNGVISWGSTAGFGDDVDI
EEECCCCCCCCCHHEEEEEECCCCEECCCCCCCCCCCEEECCCCEEECCCCCCCCCCHHH
FAERLSAEKPGYYLHNCKWVKMLSREETITVKNGQAETFTVWRTVHGNILQTDQTTQTAY
HHHHHCCCCCCCEEECCCEEEECCCCCEEEEECCCCCEEEEEEEECCCEEECCCCHHHHH
AKSRAWDGKEVASLLAWTHQMKAKNWQE
HHHCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIVNCVTASLMYYWSLPALAEQSSSEIKIVRDEYGMPHIYANDTWHLFYGYGYVVAQDRL
CEEHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCCCEEEECCEEEEEEEEEEEEEHHHH
FQMEMARRSTQGTVAEVLGKDFVKFDKDIRRNYWPDAIRAQIDALSPEDMSILQGYADGM
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
NAWIDKVNTNPETLLPKQFNTFGFTPKRWEPFDVAMIFVGTMANRFSDSTSEIDNLALLT
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALKDKYGVSQGMAVFNQLKWLVNPSAPTTIAVQESSYPLKFNQQNSQTAALLPRYDLPAP
HHHHHHCHHHHHHHHHHHHHEECCCCCCEEEEECCCCCEEECCCCCCEEEECCCCCCCCC
MLDRPAKGADGALLALTAGKNRETIAAQFAQGGANGLAGYPTTSNMWVIGKSKAQDAKAI
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEE
MVNGPQFGWYAPAYTYGIGLHGAGYDVTGNTPFAYPGLVFGHNGVISWGSTAGFGDDVDI
EEECCCCCCCCCHHEEEEEECCCCEECCCCCCCCCCCEEECCCCEEECCCCCCCCCCHHH
FAERLSAEKPGYYLHNCKWVKMLSREETITVKNGQAETFTVWRTVHGNILQTDQTTQTAY
HHHHHCCCCCCCEEECCCEEEECCCCCEEEEECCCCCEEEEEEEECCCEEECCCCHHHHH
AKSRAWDGKEVASLLAWTHQMKAKNWQE
HHHCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3016663; 3315861; 3005131; 3556321; 2989404; 1849824; 2205499; 7816145; 11601852 [H]