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The map label for this gene is acrE [H]

Identifier: 82545636

GI number: 82545636

Start: 3262097

End: 3263215

Strand: Direct

Name: acrE [H]

Synonym: SBO_3259

Alternate gene names: 82545636

Gene position: 3262097-3263215 (Clockwise)

Preceding gene: 82545634

Following gene: 82545637

Centisome position: 72.17

GC content: 52.28

Gene sequence:

>1119_bases
ATGACGAAACATGCCAGGTTTTTCCTCCTGCCCTCCTTTATTCTGATCTCCGCGGCTTTAATCGCCGGTTGTAACGATAA
GGGAGAAGAGAAAGCTCACGTCGGTGAACCGCAGGTTACCGTTCATATTGTGAAAACGGCCCCGTTAGAAGTTAAGACTG
AATTACCAGGCCGCACCAATGCTTACCGTATAGCCGAAGTTCGCCCACAGGTTAGCGGGATCGTACTGAATCGTAATTTC
ACTGAAGGCAGCGATGTACAAGCAGGCCAGTCCCTGTACCAGATCGATCCCGCGACCTATCAGGCAAATTATAACAGCGC
GAAAGGCGAACTGGCGAAAAGTGAAGCCGCCGCCGCCATCGCGCATTTGACGGTAAAACGTTACGTTCCGCTCGTGGGTA
CGAAATACATCAGCCAGCAGGAGTACGACCAGGCCATTGCTGATGCTCGCCAGGCCGATGCCGCCGTGATTGCCGCAAAA
GGCACAGTCGAAAGCGCTCGCATCAATCTCGCTTATACCAAAGTGACTGCGCCAATTAGCGGACGTATCGGCAAATCGAC
CGTGACCGAAGGCGCTCTTGTCACTAATGGGCAAACGACTGAACTGGCGACTGTCCAGCAGCTCGATCCTATCTACGTTG
ATGTGACCCAATCCAGCAACGATTTTATGAGGCTGAAGCAATCCGTAGAGCAAGGAAATTTGCATAAGGAAAACGCCACC
AGCAACGTAGAGTTGGTCATGGAAAACGGTCAAACCTATCCCCTGAAAGGTACGCTGCAATTCTCTGATGTGACCGTTGA
TGAAAGCACCGGCTCCATAACCCTACGTGCTGTCTTCCCTAACCCGCAACATACGCTTTTGCCGGGTATGTATGTGCGTG
CACGGATTGATGAAGGCGTCCAACCTGACGCCATTCTTATCCCGCAACAAGGCGTTAGCCGCACACCGCGTGGTGATGCA
ACCGTGCTGATTGTTAACGATAAAAGTCAGGTGGAAGCGCGCCCTGTCGTTGCCAGTCAGGCGATTGGCGATAAATGGTT
GATTAGCGAAGGTCTGAAATCTGGCGATCAAGTCATTGTCAGCGGCCTGCAAAAAAGCGCGTCCGGGAGAGCAGGTTAA

Upstream 100 bases:

>100_bases
ATGATAATTTGTAGGATAGCAAACTGTATTTTTCTTTCTGCGAGTTAACGCGTTGCCTTTCTGGGTAAATAACGCGCTTT
TGGTTTTTTGAGGAATAGTA

Downstream 100 bases:

>100_bases
AGCCACTACCGATACCCCCGCAGATACTGCATCGAAGTAAGGTAATCTGACATGGCAAACTTTTTTATTCGACGACCGAT
ATTTGCATGGGTGCTGGCCA

Product: AcrE

Products: NA

Alternate protein names: Protein envC [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIVKTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNF
TEGSDVQAGQSLYQIDPATYQANYNSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
GTVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKENAT
SNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNPQHTLLPGMYVRARIDEGVQPDAILIPQQGVSRTPRGDA
TVLIVNDKSQVEARPVVASQAIGDKWLISEGLKSGDQVIVSGLQKSASGRAG

Sequences:

>Translated_372_residues
MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIVKTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNF
TEGSDVQAGQSLYQIDPATYQANYNSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
GTVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKENAT
SNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNPQHTLLPGMYVRARIDEGVQPDAILIPQQGVSRTPRGDA
TVLIVNDKSQVEARPVVASQAIGDKWLISEGLKSGDQVIVSGLQKSASGRAG
>Mature_371_residues
TKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIVKTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFT
EGSDVQAGQSLYQIDPATYQANYNSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKG
TVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKENATS
NVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNPQHTLLPGMYVRARIDEGVQPDAILIPQQGVSRTPRGDAT
VLIVNDKSQVEARPVVASQAIGDKWLISEGLKSGDQVIVSGLQKSASGRAG

Specific function: May affect specific membrane functions, such as septum formation during cell division, and cell membrane permeability [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=369, Percent_Identity=98.3739837398374, Blast_Score=742, Evalue=0.0,
Organism=Escherichia coli, GI1786668, Length=370, Percent_Identity=67.8378378378378, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1789929, Length=360, Percent_Identity=50.5555555555556, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI87082036, Length=316, Percent_Identity=28.4810126582279, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081796, Length=205, Percent_Identity=26.8292682926829, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39880; Mature: 39748

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIVKTAPLEVKTELPGRTN
CCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCEEEEECCCCCCC
AYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQANYNSAKGELAKSEAAAAI
CEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEECCCCCCCCHHHHHHHHHHH
AHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKGTVESARINLAYTKVTAPIS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEEEEECCCC
GRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKENAT
CCCCCCCCCCCEEEECCCCCEEEHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
SNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNPQHTLLPGMYVRARIDEGV
CCEEEEEECCCEECEEEEEEEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEECCCCC
QPDAILIPQQGVSRTPRGDATVLIVNDKSQVEARPVVASQAIGDKWLISEGLKSGDQVIV
CCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEHHHHCCCHHHHHHHCCCCCHHHH
SGLQKSASGRAG
HHHHHCCCCCCC
>Mature Secondary Structure 
TKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIVKTAPLEVKTELPGRTN
CCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCEEEEECCCCCCC
AYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQANYNSAKGELAKSEAAAAI
CEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEECCCCCCCCHHHHHHHHHHH
AHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKGTVESARINLAYTKVTAPIS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEEEEECCCC
GRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKENAT
CCCCCCCCCCCEEEECCCCCEEEHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
SNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNPQHTLLPGMYVRARIDEGV
CCEEEEEECCCEECEEEEEEEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEECCCCC
QPDAILIPQQGVSRTPRGDATVLIVNDKSQVEARPVVASQAIGDKWLISEGLKSGDQVIV
CCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEHHHHCCCHHHHHHHCCCCCHHHH
SGLQKSASGRAG
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1720861; 9278503 [H]