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The map label for this gene is tig

Identifier: 78780132

GI number: 78780132

Start: 1637380

End: 1638825

Strand: Direct

Name: tig

Synonym: PMT9312_1747

Alternate gene names: 78780132

Gene position: 1637380-1638825 (Clockwise)

Preceding gene: 78780128

Following gene: 78780133

Centisome position: 95.8

GC content: 31.19

Gene sequence:

>1446_bases
ATGGCTAAAGAAGCATTAATAGTCAAAACCACTCCTCTACCTCAAAGTAGAATTTCATTTGAATTAGAAATACCATCTGA
GACATGCAAAACGTGTGTAAATGAGACAATCAGTACTATTAGTCGTTCGGCTAAAATTCCGGGCTTTAGACTTGGTAAAA
TCCCTAAACAAGTCTTAATCCAAAGAATTGGCATCACACAATTACATGCTTCTGCTTTAGAAAAAATAATTGATAAATCA
TGGCAAGAAGCATTAAAAATAAAATCTATTGAGCCACTAAGTGAGCCAGAATTGGTAGATGGATTTGAATCTTTACTTGC
AAAGTTTAGTCCTGAAAAATCACTTAAGTTTACTCTTCAAACTGATGTTGCCCCCGAATTAAAACTAAAGAAATCCAAAG
GACTTAGTGTTGAAATCTCAAAAACTAAGTTTGATCCTAAGTCAGTAGATGAAGCGCTAGAAAAATCTAGAAGTCAGTTT
GCAAATATTATTCCAGTAACCAATAGAGCAGCGAAATTAGGGGACATTGCTGTAGTTAGTTTCAAAGGGAAATATAAAGA
TTCTGGAAAAGAAATTGATGGTGGGACAAGTGAATCAATGGATCTTGAATTAGAAAAGAACAAAATGATTCCCGGTTTCG
TTGAGGGAATAGTAAAGATGAAAATTGGTGATACTAAAACACTAAACCTGAAATTTCCTGAAGATTATTCTCATGAGGAT
TCAAGAGGCAAAGAGGCAATCTTTGAAGTAAGTCTTAAGGATCTTAAGGAAAAAGAATTACCTGAACTTAATGACGATTT
TGCAAAACAGTCTGGAAACAAAGAATCTTTAAAAGAGTTAAAGAAAGATATTGAAAAGCAACTTAAAGAAAATTTTGAAA
AAACTCAAAAAGATATCAAAATTGAAGCTTTATTAGATGCCTTAACAAACGAATTGGTTGCTGAAATTCCAAAATCTATG
ATTGATATAGAAGTGAGAAATAATATTGAACAAACAGCGCAAAGATTTGCTCAACAAGGTCTTGATGTTAAATCTACTTT
CACTCCGGAATTAGTAAAGTCATTATCAGAGTCCACAAGGCCTCAGGCTGAAAAAAATGTTCAAAGAAATTTAGCTCTAA
AAGCATTAGCTGAAAAAGAAAACATAACAGTTGAAAAAGATGAAATTGATTTAAAAATGAAAGATTATGAAGATGCAATC
TCTCAATCTTCAAAACAAATAGATATTAAAAAGTTAACAGAAGTAATAAGTAAAGATTTACTAAAAGAAAAATTAATAAT
TTGGCTTGAAGAAAATTCCGAAGTAAAAGAAAAAACTACAAAAGCTTCTCAAGCTTCCAAAACAACAAAAGCGAAAAAAA
CAACGACAAAAACAACAAAAGCCACAAAAACTGCGACAAAAACAACAAAAGCCACAAAAACTCAAAATAAAAAAGAAAAA
AAATAA

Upstream 100 bases:

>100_bases
GATTTACTATTTTTTTTACTTTATCAAAAAATTAACTTTCAAGGGAATCACATAATGTGAAATAATTAAGATTCGGCTTA
TAGTAATAATTACAAAAAAC

Downstream 100 bases:

>100_bases
TTTATGAAATTTCCTACTAATTAAACAAAAACCCCTTAAATTATCTATAAGTGGAAAACTATTTTGTGAACTCAGAAAAA
AAACATTTAATCCAAAGCTC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MAKEALIVKTTPLPQSRISFELEIPSETCKTCVNETISTISRSAKIPGFRLGKIPKQVLIQRIGITQLHASALEKIIDKS
WQEALKIKSIEPLSEPELVDGFESLLAKFSPEKSLKFTLQTDVAPELKLKKSKGLSVEISKTKFDPKSVDEALEKSRSQF
ANIIPVTNRAAKLGDIAVVSFKGKYKDSGKEIDGGTSESMDLELEKNKMIPGFVEGIVKMKIGDTKTLNLKFPEDYSHED
SRGKEAIFEVSLKDLKEKELPELNDDFAKQSGNKESLKELKKDIEKQLKENFEKTQKDIKIEALLDALTNELVAEIPKSM
IDIEVRNNIEQTAQRFAQQGLDVKSTFTPELVKSLSESTRPQAEKNVQRNLALKALAEKENITVEKDEIDLKMKDYEDAI
SQSSKQIDIKKLTEVISKDLLKEKLIIWLEENSEVKEKTTKASQASKTTKAKKTTTKTTKATKTATKTTKATKTQNKKEK
K

Sequences:

>Translated_481_residues
MAKEALIVKTTPLPQSRISFELEIPSETCKTCVNETISTISRSAKIPGFRLGKIPKQVLIQRIGITQLHASALEKIIDKS
WQEALKIKSIEPLSEPELVDGFESLLAKFSPEKSLKFTLQTDVAPELKLKKSKGLSVEISKTKFDPKSVDEALEKSRSQF
ANIIPVTNRAAKLGDIAVVSFKGKYKDSGKEIDGGTSESMDLELEKNKMIPGFVEGIVKMKIGDTKTLNLKFPEDYSHED
SRGKEAIFEVSLKDLKEKELPELNDDFAKQSGNKESLKELKKDIEKQLKENFEKTQKDIKIEALLDALTNELVAEIPKSM
IDIEVRNNIEQTAQRFAQQGLDVKSTFTPELVKSLSESTRPQAEKNVQRNLALKALAEKENITVEKDEIDLKMKDYEDAI
SQSSKQIDIKKLTEVISKDLLKEKLIIWLEENSEVKEKTTKASQASKTTKAKKTTTKTTKATKTATKTTKATKTQNKKEK
K
>Mature_480_residues
AKEALIVKTTPLPQSRISFELEIPSETCKTCVNETISTISRSAKIPGFRLGKIPKQVLIQRIGITQLHASALEKIIDKSW
QEALKIKSIEPLSEPELVDGFESLLAKFSPEKSLKFTLQTDVAPELKLKKSKGLSVEISKTKFDPKSVDEALEKSRSQFA
NIIPVTNRAAKLGDIAVVSFKGKYKDSGKEIDGGTSESMDLELEKNKMIPGFVEGIVKMKIGDTKTLNLKFPEDYSHEDS
RGKEAIFEVSLKDLKEKELPELNDDFAKQSGNKESLKELKKDIEKQLKENFEKTQKDIKIEALLDALTNELVAEIPKSMI
DIEVRNNIEQTAQRFAQQGLDVKSTFTPELVKSLSESTRPQAEKNVQRNLALKALAEKENITVEKDEIDLKMKDYEDAIS
QSSKQIDIKKLTEVISKDLLKEKLIIWLEENSEVKEKTTKASQASKTTKAKKTTTKTTKATKTATKTTKATKTQNKKEKK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=335, Percent_Identity=29.5522388059701, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_PROM9 (Q317Y7)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_398244.1
- ProteinModelPortal:   Q317Y7
- STRING:   Q317Y7
- GeneID:   3766573
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_1747
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   PMAR74546:PMT9312_1747-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 53975; Mature: 53843

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEALIVKTTPLPQSRISFELEIPSETCKTCVNETISTISRSAKIPGFRLGKIPKQVLI
CCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHH
QRIGITQLHASALEKIIDKSWQEALKIKSIEPLSEPELVDGFESLLAKFSPEKSLKFTLQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
TDVAPELKLKKSKGLSVEISKTKFDPKSVDEALEKSRSQFANIIPVTNRAAKLGDIAVVS
CCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEE
FKGKYKDSGKEIDGGTSESMDLELEKNKMIPGFVEGIVKMKIGDTKTLNLKFPEDYSHED
ECCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHEEECCCEEEEEECCCCCCCCC
SRGKEAIFEVSLKDLKEKELPELNDDFAKQSGNKESLKELKKDIEKQLKENFEKTQKDIK
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEALLDALTNELVAEIPKSMIDIEVRNNIEQTAQRFAQQGLDVKSTFTPELVKSLSESTR
HHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
PQAEKNVQRNLALKALAEKENITVEKDEIDLKMKDYEDAISQSSKQIDIKKLTEVISKDL
CHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LKEKLIIWLEENSEVKEKTTKASQASKTTKAKKTTTKTTKATKTATKTTKATKTQNKKEK
HHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCC
K
C
>Mature Secondary Structure 
AKEALIVKTTPLPQSRISFELEIPSETCKTCVNETISTISRSAKIPGFRLGKIPKQVLI
CCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHH
QRIGITQLHASALEKIIDKSWQEALKIKSIEPLSEPELVDGFESLLAKFSPEKSLKFTLQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
TDVAPELKLKKSKGLSVEISKTKFDPKSVDEALEKSRSQFANIIPVTNRAAKLGDIAVVS
CCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEE
FKGKYKDSGKEIDGGTSESMDLELEKNKMIPGFVEGIVKMKIGDTKTLNLKFPEDYSHED
ECCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHEEECCCEEEEEECCCCCCCCC
SRGKEAIFEVSLKDLKEKELPELNDDFAKQSGNKESLKELKKDIEKQLKENFEKTQKDIK
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEALLDALTNELVAEIPKSMIDIEVRNNIEQTAQRFAQQGLDVKSTFTPELVKSLSESTR
HHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
PQAEKNVQRNLALKALAEKENITVEKDEIDLKMKDYEDAISQSSKQIDIKKLTEVISKDL
CHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LKEKLIIWLEENSEVKEKTTKASQASKTTKAKKTTTKTTKATKTATKTTKATKTQNKKEK
HHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA