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The map label for this gene is infC

Identifier: 78780114

GI number: 78780114

Start: 1615716

End: 1616288

Strand: Direct

Name: infC

Synonym: PMT9312_1729

Alternate gene names: 78780114

Gene position: 1615716-1616288 (Clockwise)

Preceding gene: 78780113

Following gene: 78780115

Centisome position: 94.53

GC content: 33.86

Gene sequence:

>573_bases
ATGCCACCACGCCCACGCTTTGACCGTCGCTCTCCTGTTAGGGAGCTCCCTAATATTAATGAAAGAATAAAATATCCCCA
ATTGAGAGTCGTTGATTCGGATGGGAAACAACTAGGAGTCATAGATAGATTAGAAGCATTAGAAATAGCCTCTCAAAGAG
AACTTGATTTAGTTTTGGTAAGTGAAAAAGCAAATCCTCCTGTTTGCAGAGTAATGGACTATGGAAAATATAAATTTGAA
CAAGAAAAGAAAGCAAAAGAAGCAAGAAAAAAATCTCATCAAACAGAAGTTAAAGAAGTAAAAATGAGATACAAAATTGA
CAAACATGATTATGACGTACGAATCGGTCAAGCTACTAAATTTTTAAAATCGGGCGATAAAGTAAAATGCACTGTATTTT
TTAGAGGCAGAGAAATTCAACACTCTAATTTAGCGGAAACACTCCTTTTAAAAATGGCTAATGATTTAGAAGAACAATCA
GAAATACAACAAAAGCCAAAAAGAGAAGGAAGAAACATGATTATGTTTTTAAGCCCTAGAAAAACTCCTCTTATTAAGAA
AGATGAAGGATAA

Upstream 100 bases:

>100_bases
CTGCTAAAAGATGCAATAATTAAGATAGAGTCTTTTTTAGACTAACTTTATGAAAAATAGATTTTTGTTCATCATCCAAT
CAATTTATTAACCAAACTGA

Downstream 100 bases:

>100_bases
GAAATTATTTTCGAAAAACTATGCCAAATGTTAAAGTGTCACTATGTATAAAAATTAATAAGTAAGGATTTTTCAAAAGT
GAGATTCCGTATTCAACAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MPPRPRFDRRSPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLEALEIASQRELDLVLVSEKANPPVCRVMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVFFRGREIQHSNLAETLLLKMANDLEEQS
EIQQKPKREGRNMIMFLSPRKTPLIKKDEG

Sequences:

>Translated_190_residues
MPPRPRFDRRSPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLEALEIASQRELDLVLVSEKANPPVCRVMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVFFRGREIQHSNLAETLLLKMANDLEEQS
EIQQKPKREGRNMIMFLSPRKTPLIKKDEG
>Mature_189_residues
PPRPRFDRRSPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLEALEIASQRELDLVLVSEKANPPVCRVMDYGKYKFEQ
EKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVFFRGREIQHSNLAETLLLKMANDLEEQSE
IQQKPKREGRNMIMFLSPRKTPLIKKDEG

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=43.7125748502994, Blast_Score=127, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22294; Mature: 22163

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRPRFDRRSPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLEALEIASQRELDLVLV
CCCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHHCCCCEEEEEE
SEKANPPVCRVMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATK
ECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHH
FLKSGDKVKCTVFFRGREIQHSNLAETLLLKMANDLEEQSEIQQKPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKDEG
CCCCCCCCCC
>Mature Secondary Structure 
PPRPRFDRRSPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLEALEIASQRELDLVLV
CCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHHCCCCEEEEEE
SEKANPPVCRVMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATK
ECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHH
FLKSGDKVKCTVFFRGREIQHSNLAETLLLKMANDLEEQSEIQQKPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKDEG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA