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The map label for this gene is rnc2 [H]

Identifier: 78780081

GI number: 78780081

Start: 1586121

End: 1586870

Strand: Direct

Name: rnc2 [H]

Synonym: PMT9312_1696

Alternate gene names: 78780081

Gene position: 1586121-1586870 (Clockwise)

Preceding gene: 78780078

Following gene: 78780083

Centisome position: 92.8

GC content: 28.13

Gene sequence:

>750_bases
ATGAAAAATATAATTAACGGAAAGAGAATTAATCAAATAACTACTTTTTTAAAATCTTTAAATATTAAATCAGAAAGATT
TTCTGAGATAATTAGAAAACAAAATATTTCAGTAATTCAAGATTTTAATCAAGCATTTATCCATTCCTCAGAAGATAAAA
TAATAAATTATGAAAAATTAGAATTCTTCGGAGATGCAGTACTCAGATTAGCTGCTTCTAATTTTATTGAGAAAAATTAT
CCTCAAATGAGTGTAGGGGAAAGATCAGAGCTAAGAGCACAAATTGTAAGTGATGAATGGTTAACTAAATTAGGGAGAAA
AATTGATATAGAGAAATTAATAATTAAAGGACCTAAAGCTCTTGGTGATCAAAATTCAAAAAATACTATTATTGGTGAAG
CTACAGAAGCTTTAATCGGTGCCGTTTACAAGTGCTTTAATTCGATTCAAGAAGTAAATCTTTGGTTAGATGATATTTGG
GAGGAAGATTCAGAAATATTTTTAAAAGCTCCATATAAGTTTAAATCCAAGACAGTATTACAAGAGTGGTGTCAAAGTAA
AGGTTTTGATTTGCCAGTCTATAAAATAATTGAAGTCTCAAAAAAAAATGGGGACCCTAAAAGATTTTCTTGCGATATAT
TTGTCGAAGGATTAAAAGAATCGTCTGCATTCGGCAAATCCCATAAACAAGCAGAAACAAATGCAGCTAAAGTTTTAATA
GAAAAATTTATAACTATAGGTAAAATCTAA

Upstream 100 bases:

>100_bases
AAGTAATTCCAGCCCTAGATAGATGATTGTCCATCTGAATTAAGATGAACAGAACCCGGCTTATGACCTGCTTTCTAATT
ATTGTGATTATTTAAATCAT

Downstream 100 bases:

>100_bases
TTTTTATAATATTTCTAAATTGGTTAGCTGAAAAGTAATGAGTTTATCCCAATTACCTCCTTCAAACAGAACAGCTGCAC
TTCTTTTTGTAACTCTTTGT

Product: RNAse III

Products: NA

Alternate protein names: Ribonuclease III 2; RNase III 2 [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKNIINGKRINQITTFLKSLNIKSERFSEIIRKQNISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKNY
PQMSVGERSELRAQIVSDEWLTKLGRKIDIEKLIIKGPKALGDQNSKNTIIGEATEALIGAVYKCFNSIQEVNLWLDDIW
EEDSEIFLKAPYKFKSKTVLQEWCQSKGFDLPVYKIIEVSKKNGDPKRFSCDIFVEGLKESSAFGKSHKQAETNAAKVLI
EKFITIGKI

Sequences:

>Translated_249_residues
MKNIINGKRINQITTFLKSLNIKSERFSEIIRKQNISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKNY
PQMSVGERSELRAQIVSDEWLTKLGRKIDIEKLIIKGPKALGDQNSKNTIIGEATEALIGAVYKCFNSIQEVNLWLDDIW
EEDSEIFLKAPYKFKSKTVLQEWCQSKGFDLPVYKIIEVSKKNGDPKRFSCDIFVEGLKESSAFGKSHKQAETNAAKVLI
EKFITIGKI
>Mature_249_residues
MKNIINGKRINQITTFLKSLNIKSERFSEIIRKQNISVIQDFNQAFIHSSEDKIINYEKLEFFGDAVLRLAASNFIEKNY
PQMSVGERSELRAQIVSDEWLTKLGRKIDIEKLIIKGPKALGDQNSKNTIIGEATEALIGAVYKCFNSIQEVNLWLDDIW
EEDSEIFLKAPYKFKSKTVLQEWCQSKGFDLPVYKIIEVSKKNGDPKRFSCDIFVEGLKESSAFGKSHKQAETNAAKVLI
EKFITIGKI

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=187, Percent_Identity=29.9465240641711, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 28478; Mature: 28478

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS50137 DS_RBD ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIINGKRINQITTFLKSLNIKSERFSEIIRKQNISVIQDFNQAFIHSSEDKIINYEKL
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHH
EFFGDAVLRLAASNFIEKNYPQMSVGERSELRAQIVSDEWLTKLGRKIDIEKLIIKGPKA
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHH
LGDQNSKNTIIGEATEALIGAVYKCFNSIQEVNLWLDDIWEEDSEIFLKAPYKFKSKTVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
QEWCQSKGFDLPVYKIIEVSKKNGDPKRFSCDIFVEGLKESSAFGKSHKQAETNAAKVLI
HHHHHHCCCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKFITIGKI
HHHHHHCCC
>Mature Secondary Structure
MKNIINGKRINQITTFLKSLNIKSERFSEIIRKQNISVIQDFNQAFIHSSEDKIINYEKL
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHH
EFFGDAVLRLAASNFIEKNYPQMSVGERSELRAQIVSDEWLTKLGRKIDIEKLIIKGPKA
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHH
LGDQNSKNTIIGEATEALIGAVYKCFNSIQEVNLWLDDIWEEDSEIFLKAPYKFKSKTVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
QEWCQSKGFDLPVYKIIEVSKKNGDPKRFSCDIFVEGLKESSAFGKSHKQAETNAAKVLI
HHHHHHCCCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKFITIGKI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]