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The map label for this gene is alr

Identifier: 78780004

GI number: 78780004

Start: 1520887

End: 1522086

Strand: Reverse

Name: alr

Synonym: PMT9312_1620

Alternate gene names: 78780004

Gene position: 1522086-1520887 (Counterclockwise)

Preceding gene: 78780006

Following gene: 78780003

Centisome position: 89.05

GC content: 31.33

Gene sequence:

>1200_bases
ATGCAAATTCGGCAAAAAAATCATGGATTTAATTCTGACAAATATCCAACTTTTGAAAAAGATATAGATCCAAAACAAAG
AGCATGGATTGAAGTTAAAGGTAAAGCAATAGAGTCAAATGTAAGGCAGTTAAGATCAAAATTAAGTAAAAGTTGTCAAT
TTATGGCAGTTGTTAAAGCAGATGGATATGGACATGATGCAAAAGTAGTATCTGAATATGCTATTAAAGGTGGAGCTTCG
CAATTAGGAGTTGCCACTTTAAAAGAAGGGATTATGCTTCGTTCTTCTGGAGTTAAAAAACCAATTCTTATTCTGGGAAA
TCTATATGCCAAAAGGGATTTAATAATATCTTTTAAAAATGATCTTATGCCAACTATTAGTAGTATAAGAGAGTGTTTAA
TTTGCAATAATATTGGGAAGCACTTTGGGTCGAAATTTTCTTTACATCTTAAAGTTGATACTGGAATGTCAAGATTAGGG
TTTGAATCTAATAAATTTGTTCAGCAATTTGAAAAAATAAAATCTTTTGAAAACATTTCAGTAGAAGGAATATATAGTCA
TTTATCATCTGCAGATGAAGATAACTCATTAGATCCCAAAAGTAGTACACAAATACAAAGACTAAAGTTTCAGGAATTAT
TACAGCAAATTAACGTTGATAGAAATCACAATATCAAGATTCATTTGGCAAATTCTGCGGGCATGCTTATTAATAAAGAC
TTTCATTTTCATATGGTACGTGTTGGGCTTTCTATGTATGGATATAGTCCTCTCGCAAAAATAGATAGAAATTTATCTCT
TAAACCAGCTTTATTTTTGAAGGTCAAAGTAGCTTTTATAAGAATTATTGATCAAGGGGTAAAAGTAAGTTACGGAGGAA
AATTTGTAAGTGGTAGAAAAACTAAGTTAGCTGTATTAAGCATTGGTTATGCAGATGGAGTCCCAAGAAATCTTTCAGGC
AAGATAAACGTTATTCATAATAATGAACTTTATCCCCAAGTTGGATCTATAACTATGGATCAAATGATGGTGGACATAAC
AGGTTCAGATGAAATTAAAATTGGTAGTACTATGTTATTACTAGGATCTGACGGAGACAAAACAATTTCTCCTTTTGATT
GGGCAAATCAATCTAACACTATTCCATGGGAAATTCTTTGTTCCTTTAAAAATAGATTGCCGAGAGTTCAAGTTGATTAG

Upstream 100 bases:

>100_bases
TAGGATGCATTTAAAACTAGAGTCTGGCCCATGCCAAAATAGAATTTACATGTCATGCTAACTGTATATTTCAATAAGCG
CATATAAATGTGCAAAGTTA

Downstream 100 bases:

>100_bases
ACATTTCGATTAAATAAAAAATTTTGAATGTTTGCAAAAAAATTGATAATGTATAAGAACTGGAGAGGTGGCTGAGTGGT
TGAAAGCGGCTCCCTGCTAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MQIRQKNHGFNSDKYPTFEKDIDPKQRAWIEVKGKAIESNVRQLRSKLSKSCQFMAVVKADGYGHDAKVVSEYAIKGGAS
QLGVATLKEGIMLRSSGVKKPILILGNLYAKRDLIISFKNDLMPTISSIRECLICNNIGKHFGSKFSLHLKVDTGMSRLG
FESNKFVQQFEKIKSFENISVEGIYSHLSSADEDNSLDPKSSTQIQRLKFQELLQQINVDRNHNIKIHLANSAGMLINKD
FHFHMVRVGLSMYGYSPLAKIDRNLSLKPALFLKVKVAFIRIIDQGVKVSYGGKFVSGRKTKLAVLSIGYADGVPRNLSG
KINVIHNNELYPQVGSITMDQMMVDITGSDEIKIGSTMLLLGSDGDKTISPFDWANQSNTIPWEILCSFKNRLPRVQVD

Sequences:

>Translated_399_residues
MQIRQKNHGFNSDKYPTFEKDIDPKQRAWIEVKGKAIESNVRQLRSKLSKSCQFMAVVKADGYGHDAKVVSEYAIKGGAS
QLGVATLKEGIMLRSSGVKKPILILGNLYAKRDLIISFKNDLMPTISSIRECLICNNIGKHFGSKFSLHLKVDTGMSRLG
FESNKFVQQFEKIKSFENISVEGIYSHLSSADEDNSLDPKSSTQIQRLKFQELLQQINVDRNHNIKIHLANSAGMLINKD
FHFHMVRVGLSMYGYSPLAKIDRNLSLKPALFLKVKVAFIRIIDQGVKVSYGGKFVSGRKTKLAVLSIGYADGVPRNLSG
KINVIHNNELYPQVGSITMDQMMVDITGSDEIKIGSTMLLLGSDGDKTISPFDWANQSNTIPWEILCSFKNRLPRVQVD
>Mature_399_residues
MQIRQKNHGFNSDKYPTFEKDIDPKQRAWIEVKGKAIESNVRQLRSKLSKSCQFMAVVKADGYGHDAKVVSEYAIKGGAS
QLGVATLKEGIMLRSSGVKKPILILGNLYAKRDLIISFKNDLMPTISSIRECLICNNIGKHFGSKFSLHLKVDTGMSRLG
FESNKFVQQFEKIKSFENISVEGIYSHLSSADEDNSLDPKSSTQIQRLKFQELLQQINVDRNHNIKIHLANSAGMLINKD
FHFHMVRVGLSMYGYSPLAKIDRNLSLKPALFLKVKVAFIRIIDQGVKVSYGGKFVSGRKTKLAVLSIGYADGVPRNLSG
KINVIHNNELYPQVGSITMDQMMVDITGSDEIKIGSTMLLLGSDGDKTISPFDWANQSNTIPWEILCSFKNRLPRVQVD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=25.9562841530055, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1790487, Length=350, Percent_Identity=30.2857142857143, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 44646; Mature: 44646

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRQKNHGFNSDKYPTFEKDIDPKQRAWIEVKGKAIESNVRQLRSKLSKSCQFMAVVKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVSEYAIKGGASQLGVATLKEGIMLRSSGVKKPILILGNLYAKRDLIISFKN
CCCCCHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCCCCEEEEECHHCCCEEEEEECH
DLMPTISSIRECLICNNIGKHFGSKFSLHLKVDTGMSRLGFESNKFVQQFEKIKSFENIS
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHCCCC
VEGIYSHLSSADEDNSLDPKSSTQIQRLKFQELLQQINVDRNHNIKIHLANSAGMLINKD
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECC
FHFHMVRVGLSMYGYSPLAKIDRNLSLKPALFLKVKVAFIRIIDQGVKVSYGGKFVSGRK
CEEEEEEHHHHHHCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEECCEEECCCC
TKLAVLSIGYADGVPRNLSGKINVIHNNELYPQVGSITMDQMMVDITGSDEIKIGSTMLL
EEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHEEEEECCCCCEEECCEEEE
LGSDGDKTISPFDWANQSNTIPWEILCSFKNRLPRVQVD
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MQIRQKNHGFNSDKYPTFEKDIDPKQRAWIEVKGKAIESNVRQLRSKLSKSCQFMAVVKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVSEYAIKGGASQLGVATLKEGIMLRSSGVKKPILILGNLYAKRDLIISFKN
CCCCCHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCCCCEEEEECHHCCCEEEEEECH
DLMPTISSIRECLICNNIGKHFGSKFSLHLKVDTGMSRLGFESNKFVQQFEKIKSFENIS
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHCCCC
VEGIYSHLSSADEDNSLDPKSSTQIQRLKFQELLQQINVDRNHNIKIHLANSAGMLINKD
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECC
FHFHMVRVGLSMYGYSPLAKIDRNLSLKPALFLKVKVAFIRIIDQGVKVSYGGKFVSGRK
CEEEEEEHHHHHHCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEECCEEECCCC
TKLAVLSIGYADGVPRNLSGKINVIHNNELYPQVGSITMDQMMVDITGSDEIKIGSTMLL
EEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHEEEEECCCCCEEECCEEEE
LGSDGDKTISPFDWANQSNTIPWEILCSFKNRLPRVQVD
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]