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The map label for this gene is bioD [H]

Identifier: 78779948

GI number: 78779948

Start: 1457991

End: 1458656

Strand: Direct

Name: bioD [H]

Synonym: PMT9312_1564

Alternate gene names: 78779948

Gene position: 1457991-1458656 (Clockwise)

Preceding gene: 78779947

Following gene: 78779949

Centisome position: 85.3

GC content: 30.63

Gene sequence:

>666_bases
ATGAATGGTATTGATAGCATTTTCAAATTTATAATCTGTGGAACAGACACTGATATTGGTAAAACTTTAATAAGTTCTTT
TTTTGTTAGAGGATTAAATTCTTTTTATTGGAAGCCTATACAAAGTGGTATTGAATCGCAAACTGATAGTCAAACTGTTG
AAACACTTGCACAAGTGAGTAGAGAGAAGATAATCAAAGAAGCTTATGTGTTCACAAAACCTTTATCTCCACATTGGGCT
TCTGAAATAGATCAAAAAACTATTAATTTTGACATGTTGAGAATACCAAAAGTAAAAGGCTCATTAATTTTAGAAACAGC
AGGTGGATTAATGGTTCCAATAACACGCAATTTTTTGCAAATAGATCAAATAAAACAATGGAACCTTCCAGTAATACTTG
TATGTAAGAGCTCACTTGGCACTCTAAACCATACTCTGCTTAGTATTGAGGCCTTAAAACGAAGAAATATTGAGATTTTA
GGTTTAGTTGTTAACGGCGAAAAACACTTAGATAATCCAAAAACACTAGTTGAATTTAGTGGAATCCCTTTAATTACTGA
GTTCCCTTACATCAAAAAAATTGATTCAAATAATTTGGATATACTATGGAAAGAACTTGACATCAAAAATAAGTTGGTCT
CACTTTTAAACTCAAAAATAAGTTAA

Upstream 100 bases:

>100_bases
CAGTGAAAGAGTTAAAAGAAATTCAAAAGTTTTGGCCAAAGAATTACAATAATACAGTTAACCTTTCATGGGAAATTGAT
ATTCAAATCATAAAGAAATT

Downstream 100 bases:

>100_bases
ATGAAATCTTTGGATTCAAACACTCCAAATCAAGATTGGCATCCAAATATTTGGCCTCCTTTTACTCAAATCAATACCAG
CAAACCGCAAATAGAAGTAA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNGIDSIFKFIICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIESQTDSQTVETLAQVSREKIIKEAYVFTKPLSPHWA
SEIDQKTINFDMLRIPKVKGSLILETAGGLMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSIEALKRRNIEIL
GLVVNGEKHLDNPKTLVEFSGIPLITEFPYIKKIDSNNLDILWKELDIKNKLVSLLNSKIS

Sequences:

>Translated_221_residues
MNGIDSIFKFIICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIESQTDSQTVETLAQVSREKIIKEAYVFTKPLSPHWA
SEIDQKTINFDMLRIPKVKGSLILETAGGLMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSIEALKRRNIEIL
GLVVNGEKHLDNPKTLVEFSGIPLITEFPYIKKIDSNNLDILWKELDIKNKLVSLLNSKIS
>Mature_221_residues
MNGIDSIFKFIICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIESQTDSQTVETLAQVSREKIIKEAYVFTKPLSPHWA
SEIDQKTINFDMLRIPKVKGSLILETAGGLMVPITRNFLQIDQIKQWNLPVILVCKSSLGTLNHTLLSIEALKRRNIEIL
GLVVNGEKHLDNPKTLVEFSGIPLITEFPYIKKIDSNNLDILWKELDIKNKLVSLLNSKIS

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=210, Percent_Identity=25.7142857142857, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324385, Length=186, Percent_Identity=36.5591397849462, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24958; Mature: 24958

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGIDSIFKFIICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIESQTDSQTVETLAQVS
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REKIIKEAYVFTKPLSPHWASEIDQKTINFDMLRIPKVKGSLILETAGGLMVPITRNFLQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCEEEECHHHHHH
IDQIKQWNLPVILVCKSSLGTLNHTLLSIEALKRRNIEILGLVVNGEKHLDNPKTLVEFS
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEEECHHHCCCCCCEEEEC
GIPLITEFPYIKKIDSNNLDILWKELDIKNKLVSLLNSKIS
CCCEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNGIDSIFKFIICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIESQTDSQTVETLAQVS
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REKIIKEAYVFTKPLSPHWASEIDQKTINFDMLRIPKVKGSLILETAGGLMVPITRNFLQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCEEEECHHHHHH
IDQIKQWNLPVILVCKSSLGTLNHTLLSIEALKRRNIEILGLVVNGEKHLDNPKTLVEFS
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEEECHHHCCCCCCEEEEC
GIPLITEFPYIKKIDSNNLDILWKELDIKNKLVSLLNSKIS
CCCEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA