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The map label for this gene is atpA [H]

Identifier: 78779928

GI number: 78779928

Start: 1439212

End: 1440729

Strand: Reverse

Name: atpA [H]

Synonym: PMT9312_1544

Alternate gene names: 78779928

Gene position: 1440729-1439212 (Counterclockwise)

Preceding gene: 78779929

Following gene: 78779927

Centisome position: 84.29

GC content: 37.55

Gene sequence:

>1518_bases
ATGGTATCTATACGCCCTGATGAAATCAGTTCAATCTTAAAACAACAAATAACTGATTATGACCAATCTGTAAGTGTAAG
CAATGTAGGAACTGTTCTGCAAATAGGTGATGGCATTGCAAGAATATATGGCTTAGATCAGGTCATGGCTGGTGAATTAT
TGGAATTTGAGGATGGTACCGAAGGTATAGCTTTAAACCTTGAAGATGATAATGTTGGAGCCGTTTTAATGGGCGAAGCA
CTGGGCGTTCAAGAAGGAAGTAATGTTAAATCTACAGGCAAAATAGCTTCTGTTCCTGTTGGCGAGGCAATGCAGGGAAG
AGTAGTTAATCCTCTAGGTCAGCCAATAGATGGTAAGGGAGAAATTCCTACAAGTGATACAAGATTGATCGAGGAAATGG
CTCCTGGAATTATCAAAAGAAGATCAGTACATGAACCAATGCAAACAGGTATAACTTCTATTGATGCAATGATTCCTGTG
GGAAGAGGTCAAAGGGAACTTATAATTGGTGATAGACAAACTGGAAAATCTGCAATTGCGATTGATACAATAATCAACCA
AAAAGGTCAAGATGTCGTATGCGTTTATGTTGCTATCGGTCAGAAATCAGCGTCTGTAGCAAATGTGGTTGAGGTTTTAA
GAGAAAAAGGAGCCCTTGATTATACCATTGTTGTTAGTGCAGGAGCATCTGAAGCAGCAGCTTTACAATACTTGGCTCCA
TATACTGGTGCTGCAATAGCTGAACACTTTATGTACCAAGGCAAAGCAACACTAGTTATTTATGATGATTTAACTAAGCA
AGCTCAAGCTTATAGACAAATGTCTCTCCTTTTAAGAAGACCACCAGGAAGAGAAGCTTATCCTGGAGATGTTTTTTATT
GTCATAGCAGACTACTTGAAAGAGCAGCAAAATTATCTGATGATATGGGCGGTGGTTCAATGACAGCATTACCAATTATT
GAAACCCAAGCTGGTGATGTTTCTGCCTATATTCCAACAAATGTTATTTCAATTACGGATGGACAAATATTCTTAAGTGC
AGATTTATTCAACTCAGGATTAAGACCAGCTATTAATGTAGGTATTTCAGTTAGTAGAGTTGGAGGAGCTGCTCAAACAA
AGGCAATTAAGAAAATTGCTGGAACACTTAAATTAGAATTAGCTCAATTTGATGAATTAGCTGCATTTTCTCAATTTGCT
TCTGATCTTGATGAGGCTACTCAACAACAACTAGAAAGAGGGAAAAGATTAAGAGAGTTGCTAAAACAAGCACAATTCTC
ACCATTAAATCTCGCAGAACAAGTTGCAGTTGTGTATGCAGGTGTTAAAGGTCTTATTGACGAAGTTCCCGTGGAAGACG
TAACTAAATTTGCTGCTGAACTTAGAGAATATCTTAAGTTGAATAAAGCAGAATTTATTGAGGAGATTCTTAAAGAGAAG
AAATTAAATGATGGCTTAGAAGCAACACTCAAAGAGGTCATAAAAGAAGTCAAATCTTCAATGCTTGCCACAGTTTAA

Upstream 100 bases:

>100_bases
AGGATCTAAAGTAATTGATGCTTCTCTTGCTTCACAAATTAGAAAACTTGGGTTGTCACTATCCAAGTAACTTTTAAATC
AACCTTAAATTCTTAAATCC

Downstream 100 bases:

>100_bases
ATTTATTTAAGGAATTATCATGGCAAATCTTAAAGAAATTAGAGATCGAATTGTTTCTGTTAAAAACACACGAAAAATAA
CAGAAGCAATGAGATTAGTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANVVEVLREKGALDYTIVVSAGASEAAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDDMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQAQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFAAELREYLKLNKAEFIEEILKEK
KLNDGLEATLKEVIKEVKSSMLATV

Sequences:

>Translated_505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANVVEVLREKGALDYTIVVSAGASEAAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDDMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQAQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFAAELREYLKLNKAEFIEEILKEK
KLNDGLEATLKEVIKEVKSSMLATV
>Mature_505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANVVEVLREKGALDYTIVVSAGASEAAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDDMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQAQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFAAELREYLKLNKAEFIEEILKEK
KLNDGLEATLKEVIKEVKSSMLATV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=495, Percent_Identity=60.6060606060606, Blast_Score=594, Evalue=1e-170,
Organism=Homo sapiens, GI4757810, Length=495, Percent_Identity=60.6060606060606, Blast_Score=594, Evalue=1e-170,
Organism=Homo sapiens, GI19913428, Length=300, Percent_Identity=29.3333333333333, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913426, Length=299, Percent_Identity=28.7625418060201, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI32189394, Length=407, Percent_Identity=24.0786240786241, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=54.7619047619048, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI1788251, Length=332, Percent_Identity=28.3132530120482, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1790170, Length=418, Percent_Identity=24.4019138755981, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=495, Percent_Identity=59.5959595959596, Blast_Score=601, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI71988080, Length=495, Percent_Identity=59.5959595959596, Blast_Score=600, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI71988074, Length=495, Percent_Identity=56.3636363636364, Blast_Score=556, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17570191, Length=292, Percent_Identity=28.7671232876712, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=296, Percent_Identity=27.3648648648649, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25144756, Length=429, Percent_Identity=23.3100233100233, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988068, Length=78, Percent_Identity=43.5897435897436, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=64, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=495, Percent_Identity=58.5858585858586, Blast_Score=583, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6319603, Length=299, Percent_Identity=28.7625418060201, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=395, Percent_Identity=25.3164556962025, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=58.8118811881188, Blast_Score=599, Evalue=1e-171,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24638766, Length=437, Percent_Identity=24.9427917620137, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28574560, Length=400, Percent_Identity=25.5, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54243; Mature: 54243

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKG
CCEEEEECCCCCCEEEECCHHCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCCCCCCCCC
EIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKSAIA
CCCCHHHHHHHHHCCHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCEEEECCCCCCCCEEE
IDTIINQKGQDVVCVYVAIGQKSASVANVVEVLREKGALDYTIVVSAGASEAAALQYLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
RAAKLSDDMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINV
HHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEEHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQAQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFAAELREYLKLNKAEFIEEILKEK
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLNDGLEATLKEVIKEVKSSMLATV
CCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKG
CCEEEEECCCCCCEEEECCHHCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCCCCCCCCC
EIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKSAIA
CCCCHHHHHHHHHCCHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCEEEECCCCCCCCEEE
IDTIINQKGQDVVCVYVAIGQKSASVANVVEVLREKGALDYTIVVSAGASEAAALQYLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
RAAKLSDDMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINV
HHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEEHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQAQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFAAELREYLKLNKAEFIEEILKEK
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLNDGLEATLKEVIKEVKSSMLATV
CCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA