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The map label for this gene is dspA [H]

Identifier: 78779823

GI number: 78779823

Start: 1352052

End: 1354121

Strand: Direct

Name: dspA [H]

Synonym: PMT9312_1439

Alternate gene names: 78779823

Gene position: 1352052-1354121 (Clockwise)

Preceding gene: 78779822

Following gene: 78779826

Centisome position: 79.1

GC content: 34.11

Gene sequence:

>2070_bases
ATGGTAGATACCAAGAACCAAGATAGTAGAGATTATAATAGTACCAGTGATAATGAAGATTTTCATAACAACTATTGGAC
TAATAGGATAATTGCTTGGTGGAGTGGGTTTAGTTTAAGAACAAAATTGTTAGCGATAGCAACTCTCGTTGTAAGTCTCC
TAATGACAGGAATAACATTTTTTGCACTAAATAGTATTCAACGAGATGCAGGAATGAATGATACTAGATATGCTCGAGAT
CTTGGATTATTGTTATCAGGTAATGTCACAGAATTAGTTGCTAATAATCAAAAAAAAGAAATCTCAAATGTAGCTGAAAA
GTTTTGGAGATCAAGTCGGAATCTACGTTACATATTTTTTACTGATGCTGAGGACATTGTTCAACTTGGAATACCGATTA
GTGCCACTACAACAAGTTCAGATAGTCAATTACAGCTCACTAGAAGGTTAAAACTTCCATCAGAATTAAAGAAAAGACCG
CAATTTCCTTTAGTTAGGCAGCATGTTACACCTCAAGGTCAAGTAACAGATGTATTTGTCCCAATGCTTTGGAAAGGGAA
ATATCTTGGAACTTTAGCTTTAGGAGTTACACCTAATAAAAAAGCCTTGGCGAGTGCTGCACTTACAAGAGAAATTACCA
TAGCAGTTTTTATCTCTATTTGGGTTTTAGTAATACTGGGAGCTGTATTCAATGCACTAACAATCACTAGACCTGTAAGA
GAGTTAGTAAGGGGTGTCAGGGAAATTTCTAAAGGAAACTTTAAATCAAGAATTTCTATACCTATGACAGGAGATTTAGG
AGAACTTTTAAATGGATTTAACCGAATGGCTACTCAGTTAGAAAATTATGACGAGGCAAATATTGAAGAACTTAAAGCCG
CTCAAATAAAGCAGCAATCACTAATAGCTACTATGGCTGATGGTGCAATATTATTGGATTCCCAAGGAAAGATAGTACTT
ACTAATCCAACCGCAAAAAGATTATTCCGTTGGGAAGGAAGATTCTTGGAAGGAAAATATTTTTTAAATGAGATCCCCGA
AATTTTATCTAATGACTTACATACAAATATAGAATCTATTCTAAATAGAGAAAAAGAGAAAGATGATTTAAGGTTTAGCT
TAGGAGAACCGGCAAGAACTTTAAGGATTGTTTTACAATCAGTCTTAGATACAAACAAAGTTGAATTAAAAGGTATCGCC
GTAACAATTCAAGATCTTACAAGAGAGGTAGAACTAAATGCGGCACAAAACAGATTTATTAGTAATGTTTCGCACGAATT
AAGAACACCACTTTTTAACATAAAAAGTTACGTGGAGACCTTACATGATTTAAAAGACCAACTCTCAAACGAAGAACAAC
TCGAATTTCTGGGTATTGCGAATTCAGAGACTGATAGGCTTACAAGACTAGTGAATGATGTATTAGATTTATCAAGATTG
GAGTCAGGGAAAATAATTCAATTAGAAGAAATGGATATAAAAGCGGCAATAGAACAGACTCTCAGAAATTACAGACTTAA
CGCTACAGAAAAAAATGTTTCATTAGCACATGATATAGAAGAAAATATACCTCCAATTCTTGGTAATTTTGATTTACTTT
TACAAGTTTTTGATAATTTACTGGGCAATGGATTAAAATTCAGTCCCAAAAATAGCAACCTAATGATAAGAGCTTATGCT
TGGCCAGATTCCTGTCCTGCTTTTCCTCCAAGTAAACAAAATGATAGAGCGCCTCAATGCGAGTTAGTTTCACCATTACC
AAAAGTAAGAATTGAGATTGCCGATACAGGTTCTGGGATATCTCAAACGGATCAAGAGAAGATTTTTGACCGTTTTTTTA
GAGTAGAGAATGCTGTTCATACTGAGCAAGGAACAGGTTTGGGGTTATCTATAGTGAGAGGAATAATTGAAAAACATGGT
GGAGAAATTCGAATGGCTAGTGAATTAGGAATTGGAACAACCTTCTGGTTTGATTTAGCATTGGCACAATCAGATAAAGA
TGAATTATTAACTCAAACTATTAACAATACAGATAATTTTTCAAACTCTGAAGTAAGTAAATTCATCTAA

Upstream 100 bases:

>100_bases
AGCATATAAAAATCTTAAAGAAATAAATTTTGAGGGAATTTACTTTAGAAATGATATAGGGCATCAAGTTAGAAAAAAAT
TTTCTAGGGAGAATTAGCTT

Downstream 100 bases:

>100_bases
TTATTATCTAGTCCTCTAAAAATATTCTGAACATTTTGATCAGGAACTACCCTATGAGGGGCACCACTAAATATCTGTTC
AAAGTTAGAAAAAGAATCTT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MVDTKNQDSRDYNSTSDNEDFHNNYWTNRIIAWWSGFSLRTKLLAIATLVVSLLMTGITFFALNSIQRDAGMNDTRYARD
LGLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFTDAEDIVQLGIPISATTTSSDSQLQLTRRLKLPSELKKRP
QFPLVRQHVTPQGQVTDVFVPMLWKGKYLGTLALGVTPNKKALASAALTREITIAVFISIWVLVILGAVFNALTITRPVR
ELVRGVREISKGNFKSRISIPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSLIATMADGAILLDSQGKIVL
TNPTAKRLFRWEGRFLEGKYFLNEIPEILSNDLHTNIESILNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKVELKGIA
VTIQDLTREVELNAAQNRFISNVSHELRTPLFNIKSYVETLHDLKDQLSNEEQLEFLGIANSETDRLTRLVNDVLDLSRL
ESGKIIQLEEMDIKAAIEQTLRNYRLNATEKNVSLAHDIEENIPPILGNFDLLLQVFDNLLGNGLKFSPKNSNLMIRAYA
WPDSCPAFPPSKQNDRAPQCELVSPLPKVRIEIADTGSGISQTDQEKIFDRFFRVENAVHTEQGTGLGLSIVRGIIEKHG
GEIRMASELGIGTTFWFDLALAQSDKDELLTQTINNTDNFSNSEVSKFI

Sequences:

>Translated_689_residues
MVDTKNQDSRDYNSTSDNEDFHNNYWTNRIIAWWSGFSLRTKLLAIATLVVSLLMTGITFFALNSIQRDAGMNDTRYARD
LGLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFTDAEDIVQLGIPISATTTSSDSQLQLTRRLKLPSELKKRP
QFPLVRQHVTPQGQVTDVFVPMLWKGKYLGTLALGVTPNKKALASAALTREITIAVFISIWVLVILGAVFNALTITRPVR
ELVRGVREISKGNFKSRISIPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSLIATMADGAILLDSQGKIVL
TNPTAKRLFRWEGRFLEGKYFLNEIPEILSNDLHTNIESILNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKVELKGIA
VTIQDLTREVELNAAQNRFISNVSHELRTPLFNIKSYVETLHDLKDQLSNEEQLEFLGIANSETDRLTRLVNDVLDLSRL
ESGKIIQLEEMDIKAAIEQTLRNYRLNATEKNVSLAHDIEENIPPILGNFDLLLQVFDNLLGNGLKFSPKNSNLMIRAYA
WPDSCPAFPPSKQNDRAPQCELVSPLPKVRIEIADTGSGISQTDQEKIFDRFFRVENAVHTEQGTGLGLSIVRGIIEKHG
GEIRMASELGIGTTFWFDLALAQSDKDELLTQTINNTDNFSNSEVSKFI
>Mature_689_residues
MVDTKNQDSRDYNSTSDNEDFHNNYWTNRIIAWWSGFSLRTKLLAIATLVVSLLMTGITFFALNSIQRDAGMNDTRYARD
LGLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFTDAEDIVQLGIPISATTTSSDSQLQLTRRLKLPSELKKRP
QFPLVRQHVTPQGQVTDVFVPMLWKGKYLGTLALGVTPNKKALASAALTREITIAVFISIWVLVILGAVFNALTITRPVR
ELVRGVREISKGNFKSRISIPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSLIATMADGAILLDSQGKIVL
TNPTAKRLFRWEGRFLEGKYFLNEIPEILSNDLHTNIESILNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKVELKGIA
VTIQDLTREVELNAAQNRFISNVSHELRTPLFNIKSYVETLHDLKDQLSNEEQLEFLGIANSETDRLTRLVNDVLDLSRL
ESGKIIQLEEMDIKAAIEQTLRNYRLNATEKNVSLAHDIEENIPPILGNFDLLLQVFDNLLGNGLKFSPKNSNLMIRAYA
WPDSCPAFPPSKQNDRAPQCELVSPLPKVRIEIADTGSGISQTDQEKIFDRFFRVENAVHTEQGTGLGLSIVRGIIEKHG
GEIRMASELGIGTTFWFDLALAQSDKDELLTQTINNTDNFSNSEVSKFI

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc; May Activate Atoc By Phosphorylation. [C]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=411, Percent_Identity=25.7907542579075, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789149, Length=269, Percent_Identity=30.1115241635688, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=27.7777777777778, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=27.719298245614, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082128, Length=314, Percent_Identity=26.4331210191083, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=29.3436293436293, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1786600, Length=415, Percent_Identity=25.0602409638554, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=23.4432234432234, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788279, Length=226, Percent_Identity=25.2212389380531, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=27.0042194092827, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77586; Mature: 77586

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDTKNQDSRDYNSTSDNEDFHNNYWTNRIIAWWSGFSLRTKLLAIATLVVSLLMTGITF
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
FALNSIQRDAGMNDTRYARDLGLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFF
HHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
TDAEDIVQLGIPISATTTSSDSQLQLTRRLKLPSELKKRPQFPLVRQHVTPQGQVTDVFV
ECHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHCCCCCHHHHCCCCCCCCHHHHH
PMLWKGKYLGTLALGVTPNKKALASAALTREITIAVFISIWVLVILGAVFNALTITRPVR
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVRGVREISKGNFKSRISIPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQS
HHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LIATMADGAILLDSQGKIVLTNPTAKRLFRWEGRFLEGKYFLNEIPEILSNDLHTNIESI
HHHHHCCCEEEEECCCCEEEECCHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHH
LNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKVELKGIAVTIQDLTREVELNAAQNRFI
HCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHH
SNVSHELRTPLFNIKSYVETLHDLKDQLSNEEQLEFLGIANSETDRLTRLVNDVLDLSRL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHC
ESGKIIQLEEMDIKAAIEQTLRNYRLNATEKNVSLAHDIEENIPPILGNFDLLLQVFDNL
CCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
LGNGLKFSPKNSNLMIRAYAWPDSCPAFPPSKQNDRAPQCELVSPLPKVRIEIADTGSGI
HCCCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
SQTDQEKIFDRFFRVENAVHTEQGTGLGLSIVRGIIEKHGGEIRMASELGIGTTFWFDLA
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHH
LAQSDKDELLTQTINNTDNFSNSEVSKFI
HHCCCHHHHHHHHHCCCCCCCCCHHHHCC
>Mature Secondary Structure
MVDTKNQDSRDYNSTSDNEDFHNNYWTNRIIAWWSGFSLRTKLLAIATLVVSLLMTGITF
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
FALNSIQRDAGMNDTRYARDLGLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFF
HHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
TDAEDIVQLGIPISATTTSSDSQLQLTRRLKLPSELKKRPQFPLVRQHVTPQGQVTDVFV
ECHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHCCCCCHHHHCCCCCCCCHHHHH
PMLWKGKYLGTLALGVTPNKKALASAALTREITIAVFISIWVLVILGAVFNALTITRPVR
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVRGVREISKGNFKSRISIPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQS
HHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LIATMADGAILLDSQGKIVLTNPTAKRLFRWEGRFLEGKYFLNEIPEILSNDLHTNIESI
HHHHHCCCEEEEECCCCEEEECCHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHH
LNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKVELKGIAVTIQDLTREVELNAAQNRFI
HCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHH
SNVSHELRTPLFNIKSYVETLHDLKDQLSNEEQLEFLGIANSETDRLTRLVNDVLDLSRL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHC
ESGKIIQLEEMDIKAAIEQTLRNYRLNATEKNVSLAHDIEENIPPILGNFDLLLQVFDNL
CCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
LGNGLKFSPKNSNLMIRAYAWPDSCPAFPPSKQNDRAPQCELVSPLPKVRIEIADTGSGI
HCCCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
SQTDQEKIFDRFFRVENAVHTEQGTGLGLSIVRGIIEKHGGEIRMASELGIGTTFWFDLA
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHH
LAQSDKDELLTQTINNTDNFSNSEVSKFI
HHCCCHHHHHHHHHCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]