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The map label for this gene is lpxA [H]

Identifier: 78779817

GI number: 78779817

Start: 1345511

End: 1346353

Strand: Reverse

Name: lpxA [H]

Synonym: PMT9312_1433

Alternate gene names: 78779817

Gene position: 1346353-1345511 (Counterclockwise)

Preceding gene: 78779818

Following gene: 78779816

Centisome position: 78.77

GC content: 33.21

Gene sequence:

>843_bases
ATGAAGAATAAAAATAATAAATTAAAGGCAGCATTTGGAGGCGTTAAAGTTCATCCAAATGCCTTTGTTGACTCAAGTGC
AGAATTGCATGATGGAGTCATTATCTCTCAAGGAGCTATTGTCGGTCCTAATGTGTCCATTGGGAGAGGAACCGAAATAG
GAGCTAATGCTGTTATTAAGGGAAGAACTCAAATTGGTAATAACAATAAAGTGTTCCCAAATGTTTTTATAGGTCTGGAT
CCGCAAGATCTTAAATATAAAGGGGCCTCTACGGAGGTGATTATTGGTGATAATAATACTTTTAGAGAATGCGTAACTAT
AAATAAGGCAACTGATGAAGGAGAAAAAACTATTATTGGTAATAATAATTTGTTAATGGCTTACACTCATATAGGCCATA
ATTGTGAACTTGGTAATTGGATAGTTTTATCAAATAGTGTTCAAGTTGCAGGACATGTAAAGATTGAAGATAAAGCGATT
ATTGGTGGCTGTTTAGGTATTCATCAATTTGTACATATTGGATATTTAGCAATGATTGGAGGAATGACGAGAGTAGATAG
AGATGTACCTCCTTTTTGTTTAGCTGAAGGACATCCAGGAAGATTGAGAGGTCTAAATAGGATTGGGATTAAAAGAAGTG
GTTTGATGGAAAATAAGGACTTTGATTTAAAACTTTTGCAAAACACGTGGAATTTACTTTTTAAATCTAATTATGTAATT
GCTGATGCATTGGAAATGGCATTAAAAGACACATTAGATCTTTCTTCAAAACAATTATGTGATTTTTTAAAAGAATCAAT
ATCAAAAGAAAGACGAGGCCCAATGCCTTTAATAAATGAATGA

Upstream 100 bases:

>100_bases
ATTAAAAGACAAAGATTTGGCAAGGTTAAAGGAGAGGCACACGTTGATGGTAATTTGGTTTGTGCTGGAGAATTAATGTT
CTCATTAGTTGATTAATAAT

Downstream 100 bases:

>100_bases
ATAAAAAGATATTTATCAGTACCGGAGAAGTCTCTGGAGATTTACATGGGGGGTTATTGTCAAAAGCGTTATTTGATGAA
GCGGAAAAAAAATCTTTAGA

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKNKNNKLKAAFGGVKVHPNAFVDSSAELHDGVIISQGAIVGPNVSIGRGTEIGANAVIKGRTQIGNNNKVFPNVFIGLD
PQDLKYKGASTEVIIGDNNTFRECVTINKATDEGEKTIIGNNNLLMAYTHIGHNCELGNWIVLSNSVQVAGHVKIEDKAI
IGGCLGIHQFVHIGYLAMIGGMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDLKLLQNTWNLLFKSNYVI
ADALEMALKDTLDLSSKQLCDFLKESISKERRGPMPLINE

Sequences:

>Translated_280_residues
MKNKNNKLKAAFGGVKVHPNAFVDSSAELHDGVIISQGAIVGPNVSIGRGTEIGANAVIKGRTQIGNNNKVFPNVFIGLD
PQDLKYKGASTEVIIGDNNTFRECVTINKATDEGEKTIIGNNNLLMAYTHIGHNCELGNWIVLSNSVQVAGHVKIEDKAI
IGGCLGIHQFVHIGYLAMIGGMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDLKLLQNTWNLLFKSNYVI
ADALEMALKDTLDLSSKQLCDFLKESISKERRGPMPLINE
>Mature_280_residues
MKNKNNKLKAAFGGVKVHPNAFVDSSAELHDGVIISQGAIVGPNVSIGRGTEIGANAVIKGRTQIGNNNKVFPNVFIGLD
PQDLKYKGASTEVIIGDNNTFRECVTINKATDEGEKTIIGNNNLLMAYTHIGHNCELGNWIVLSNSVQVAGHVKIEDKAI
IGGCLGIHQFVHIGYLAMIGGMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDLKLLQNTWNLLFKSNYVI
ADALEMALKDTLDLSSKQLCDFLKESISKERRGPMPLINE

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=260, Percent_Identity=38.4615384615385, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1786376, Length=230, Percent_Identity=30.8695652173913, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 30546; Mature: 30546

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKNNKLKAAFGGVKVHPNAFVDSSAELHDGVIISQGAIVGPNVSIGRGTEIGANAVIK
CCCCCCEEEEEECCEEECCCCCCCCCCCHHCCEEEECCEEECCCCCCCCCCCCCCCEEEE
GRTQIGNNNKVFPNVFIGLDPQDLKYKGASTEVIIGDNNTFRECVTINKATDEGEKTIIG
CCEEECCCCEECCEEEEECCCHHCEECCCCEEEEECCCCCEEEEEEEECCCCCCCEEEEC
NNNLLMAYTHIGHNCELGNWIVLSNSVQVAGHVKIEDKAIIGGCLGIHQFVHIGYLAMIG
CCCEEEEEEECCCCCCCCCEEEEECCEEEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHC
GMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDLKLLQNTWNLLFKSNYVI
CCHHHCCCCCCEEEECCCCHHHCCCHHCCCCCCCCCCCCCCCCEEHHHHHHHEEECCEEH
ADALEMALKDTLDLSSKQLCDFLKESISKERRGPMPLINE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKNKNNKLKAAFGGVKVHPNAFVDSSAELHDGVIISQGAIVGPNVSIGRGTEIGANAVIK
CCCCCCEEEEEECCEEECCCCCCCCCCCHHCCEEEECCEEECCCCCCCCCCCCCCCEEEE
GRTQIGNNNKVFPNVFIGLDPQDLKYKGASTEVIIGDNNTFRECVTINKATDEGEKTIIG
CCEEECCCCEECCEEEEECCCHHCEECCCCEEEEECCCCCEEEEEEEECCCCCCCEEEEC
NNNLLMAYTHIGHNCELGNWIVLSNSVQVAGHVKIEDKAIIGGCLGIHQFVHIGYLAMIG
CCCEEEEEEECCCCCCCCCEEEEECCEEEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHC
GMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDLKLLQNTWNLLFKSNYVI
CCHHHCCCCCCEEEECCCCHHHCCCHHCCCCCCCCCCCCCCCCEEHHHHHHHEEECCEEH
ADALEMALKDTLDLSSKQLCDFLKESISKERRGPMPLINE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA