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The map label for this gene is argD [H]

Identifier: 78779781

GI number: 78779781

Start: 1312373

End: 1313626

Strand: Direct

Name: argD [H]

Synonym: PMT9312_1397

Alternate gene names: 78779781

Gene position: 1312373-1313626 (Clockwise)

Preceding gene: 78779780

Following gene: 78779782

Centisome position: 76.78

GC content: 35.41

Gene sequence:

>1254_bases
GTGGAATTGGTAGACGCACCGCACTCAAAATGCGGCACCTTCGGGTATGTCGGTTCAAGTCCGACCGCTCCCACTTTGAT
GAATACTTATAGTCGATTCGATATATCTTTCAAAAAAGGTAAAGGTTGTTGGCTATGGGACAAAAAAGGTAAAAAGTATC
TTGATGCAGTCGCTGGTATAGCAACTTGTAGTCTTGGTCATAGCGATAGAGTTTTAAGACGAAGACTATCAACTCAACTA
AAAAAGATTCAACACATTTCAAATCTCTATAACATTGAAGAACAAGAACAATTAAGCAAAACTCTAACGAATATTAGTTG
TGCTGAAAGCGTCTTTTTCTGCAACAGTGGTGCGGAAGCAAATGAATCAGCAATTAAATTAATTAAAAAATATGGGAACA
CCACAAATAAAGGTAAAGAATCAATTATTCTCTCAGCAGAATCCAGCTTTCATGGCAGAACGCTGGCAGCCTTGAGTGCT
ACCGGTCAGCCAAAATACCAAGAAGGTTTCGAACCAATGATTAAAGGGTTCAAATTTTTTAAATTTAACAATTTTGATTC
AGTAAAAAAATTATTTGAAGAGTGTGAAAATAAAGATCAAAAAATTTCTGGCGTTTTAGTTGAACCAATACAAGGAGAAG
GTGGCGTAATTCCTGGAAGTAAAATATTTTTTAAAAGCCTAAGAGAAATATGTGATAAATATGGTTCTCTTCTAATTTTT
GATGAGGTCCAAAGTGGGGTAGGTCGAACTGGAAAAATGTGGGGTTATGAGAATTTAGGAATTGAACCTGATGGATTCAC
CCTCGCTAAAGGATTAGGAGGAGGTCATGCAATTGGAGCATTATTGGTAAAAGAAAAAGCTAACATTTTTTCACCAGGAG
ATCATGCCAGCACTTTTGGAGGGAACCCATTCGCATGTAAGGCTGCCTTAACTGTATTAGAAGAAATAAAGAGAAGAAAT
CTTATAAATAATGTTTATCTAAGAGGGGACCAATTAAGCGCTGGATTTGAAGAATTGTCAAAAAAATTTCCAAATATTAT
TAGGGGGAAAAGAGGTTTAGGTTTAATACAAGGTCTTGTTATCAATAATGATTATGCTGATGCTAAAGAAATTACATTAA
AAGCTTTTGACAAAGGATTACTAGTAGTTCCAGCAGGAGGGAACGTTGTTAGGATTGTCCCACCATTAATTATATCTCGA
AGAGAAATTAATATTCTTTTAGATAAGCTGAATTCAATTTTTGAGGAGTTATAG

Upstream 100 bases:

>100_bases
TATCTTAATCGCTCTTCCTTAACCACCAAACGCATAGTCAATAAAATGAATTTTGTTATAATAAAAAAGTTCATTATTTT
TCAAAAGCCTTGGGAGCGTG

Downstream 100 bases:

>100_bases
CACTTTAAATTTTGAAAAATGCAAATTTAAAAAATTTTAAATTATTATCACCCAAATATGAAAGGGATAATATCAAGTTA
GGTTTATCTAGAATTAAAAA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKKGKKYLDAVAGIATCSLGHSDRVLRRRLSTQL
KKIQHISNLYNIEEQEQLSKTLTNISCAESVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILSAESSFHGRTLAALSA
TGQPKYQEGFEPMIKGFKFFKFNNFDSVKKLFEECENKDQKISGVLVEPIQGEGGVIPGSKIFFKSLREICDKYGSLLIF
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFSPGDHASTFGGNPFACKAALTVLEEIKRRN
LINNVYLRGDQLSAGFEELSKKFPNIIRGKRGLGLIQGLVINNDYADAKEITLKAFDKGLLVVPAGGNVVRIVPPLIISR
REINILLDKLNSIFEEL

Sequences:

>Translated_417_residues
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKKGKKYLDAVAGIATCSLGHSDRVLRRRLSTQL
KKIQHISNLYNIEEQEQLSKTLTNISCAESVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILSAESSFHGRTLAALSA
TGQPKYQEGFEPMIKGFKFFKFNNFDSVKKLFEECENKDQKISGVLVEPIQGEGGVIPGSKIFFKSLREICDKYGSLLIF
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFSPGDHASTFGGNPFACKAALTVLEEIKRRN
LINNVYLRGDQLSAGFEELSKKFPNIIRGKRGLGLIQGLVINNDYADAKEITLKAFDKGLLVVPAGGNVVRIVPPLIISR
REINILLDKLNSIFEEL
>Mature_417_residues
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKKGKKYLDAVAGIATCSLGHSDRVLRRRLSTQL
KKIQHISNLYNIEEQEQLSKTLTNISCAESVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILSAESSFHGRTLAALSA
TGQPKYQEGFEPMIKGFKFFKFNNFDSVKKLFEECENKDQKISGVLVEPIQGEGGVIPGSKIFFKSLREICDKYGSLLIF
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFSPGDHASTFGGNPFACKAALTVLEEIKRRN
LINNVYLRGDQLSAGFEELSKKFPNIIRGKRGLGLIQGLVINNDYADAKEITLKAFDKGLLVVPAGGNVVRIVPPLIISR
REINILLDKLNSIFEEL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=31.1224489795918, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI284507298, Length=305, Percent_Identity=33.7704918032787, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=26.7123287671233, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=27.2727272727273, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=27.511961722488, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442709, Length=358, Percent_Identity=28.7709497206704, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI188536080, Length=440, Percent_Identity=25.9090909090909, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI38679950, Length=440, Percent_Identity=25.9090909090909, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI38679946, Length=440, Percent_Identity=25.9090909090909, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=22.9314420803783, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=42.257217847769, Blast_Score=307, Evalue=7e-85,
Organism=Escherichia coli, GI1789759, Length=382, Percent_Identity=35.8638743455497, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI145693181, Length=387, Percent_Identity=34.3669250645995, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=30.272952853598, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=29.3103448275862, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786349, Length=318, Percent_Identity=27.9874213836478, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786991, Length=407, Percent_Identity=25.0614250614251, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=33.9473684210526, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=37.1747211895911, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=30.365296803653, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=414, Percent_Identity=26.5700483091787, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=441, Percent_Identity=27.6643990929705, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71981843, Length=166, Percent_Identity=29.5180722891566, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=39.1521197007481, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=393, Percent_Identity=31.5521628498728, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6321456, Length=433, Percent_Identity=26.7898383371824, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=431, Percent_Identity=23.4338747099768, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=32.987012987013, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI28574759, Length=434, Percent_Identity=28.8018433179723, Blast_Score=151, Evalue=8e-37,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=28.246013667426, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281366494, Length=440, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24667139, Length=440, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24667143, Length=440, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=25.5269320843091, Blast_Score=121, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45765; Mature: 45765

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKKGKKYLDAVAGI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCEEEEECCCCEEEECCCCHHHHHHHHHH
ATCSLGHSDRVLRRRLSTQLKKIQHISNLYNIEEQEQLSKTLTNISCAESVFFCNSGAEA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCC
NESAIKLIKKYGNTTNKGKESIILSAESSFHGRTLAALSATGQPKYQEGFEPMIKGFKFF
CHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEE
KFNNFDSVKKLFEECENKDQKISGVLVEPIQGEGGVIPGSKIFFKSLREICDKYGSLLIF
EECCHHHHHHHHHHHCCCCCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEE
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFSPGDHASTFG
HHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
GNPFACKAALTVLEEIKRRNLINNVYLRGDQLSAGFEELSKKFPNIIRGKRGLGLIQGLV
CCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCHHHHCCCCCCHHHEEEE
INNDYADAKEITLKAFDKGLLVVPAGGNVVRIVPPLIISRREINILLDKLNSIFEEL
EECCCCCHHHHHHEECCCCEEEEECCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKKGKKYLDAVAGI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCEEEEECCCCEEEECCCCHHHHHHHHHH
ATCSLGHSDRVLRRRLSTQLKKIQHISNLYNIEEQEQLSKTLTNISCAESVFFCNSGAEA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCC
NESAIKLIKKYGNTTNKGKESIILSAESSFHGRTLAALSATGQPKYQEGFEPMIKGFKFF
CHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEE
KFNNFDSVKKLFEECENKDQKISGVLVEPIQGEGGVIPGSKIFFKSLREICDKYGSLLIF
EECCHHHHHHHHHHHCCCCCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEE
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFSPGDHASTFG
HHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
GNPFACKAALTVLEEIKRRNLINNVYLRGDQLSAGFEELSKKFPNIIRGKRGLGLIQGLV
CCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCHHHHCCCCCCHHHEEEE
INNDYADAKEITLKAFDKGLLVVPAGGNVVRIVPPLIISRREINILLDKLNSIFEEL
EECCCCCHHHHHHEECCCCEEEEECCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]