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The map label for this gene is murA

Identifier: 78779780

GI number: 78779780

Start: 1310453

End: 1311823

Strand: Direct

Name: murA

Synonym: PMT9312_1396

Alternate gene names: 78779780

Gene position: 1310453-1311823 (Clockwise)

Preceding gene: 78779775

Following gene: 78779781

Centisome position: 76.67

GC content: 33.33

Gene sequence:

>1371_bases
ATGATTTGCGGAAGCAAAAAGAAGGCATATCTTAAATCGCAAAATTTAAAGATTCTTGGCCAAGGCAAGTTAAATGGAAT
AGTTAAGATAAATGGCGCGAAGAATTCGGCCTTAGTTTTATTGGCATCATCATTGCTAACTAATGAAAAAATAATACTTG
AAAATATTCCTTATCTTACTGATATTGAGAAAATGGGAAATATCCTAAAAAATTTAGGAGTTAATTTAATTGATAAAAAT
GACCAATTAGAGATAGATCCAACAAATATTTCCATTAAAGAACTTCCATATGAACTAGTTAATGGATTAAGAGCTAGTTT
CTTTTGCATAGGTGCACTATTAACTAAATTTGGAGAAGCTCAAGTACCCTTACCAGGTGGATGCAATATTGGATCAAGGC
CAATAGACGAGCACATTAATGGACTCATCGCATTAGGCGCAGACATTATTATTGAAGAGGGAATTGTCAAGGCAAAGATA
AGGGGAAACAAAAATAAACTTCATGGTACTCATATTAAATTGAAGTGTCCAAGCGTAGGAGCAACTGAAACTTTAATAAT
GGCTGCATCTTTAGCGGAAGGAAGAACTACTATTGAGAATGCTGCAAGAGAGCCTGAAATTCAGGATTTATGCCATATGC
TTAATAAAATGGGGGCAAAGATTTACGACTCCGGTAAAGAAACAATAATTATTGATGGTGTTAATAAGCTAGGTGGTTGT
ACTCATAAAGTAATTCCAGACCGAATAGAAGCTGGAACTTTTCTAATAGCTGCTGCTGCAACTTCCTCTTCAATAACAAT
TTCTCCTGTGATCCCTCATCATCTTGAAGCTGTTACTAATAAGCTTCAAGAAAGTGGGAGTAAAATTACTATTAAAGGTA
ATTCGATTTCAATCAAGAGTAAGGAGATTAAAGGAGTAGATATTGAAACAGCTCCTTTTCCAGGATTTCCTACTGATTTG
CAAGCACCATTTACAGCACTAATGACAATAGCAAATGGTGAATCAAAGATCACTGAAACGATTTTCGAAAACAGAATGAA
TCATATTCATTTACTTAATAAAATGGGTGCCCGTATAAAACTAAATGAAAACGTAGCTTACATTAAAGGTGTTAAAACAC
TTAATGGGATGGATCTAATAGGCTCAGATTTAAGGTCATCAGCCGCATTAATAATTGCTGGAATCATCGCAGAAGGTACT
AGTAATATCTATGGTTTAGAACATTTAGATAGAGGTTATGAAAATTTTGAATTAAAACTAAAAAAATTAGGTATTAAAAT
AACTAGGGAGTTTAATAAAAGTACTTTTGAGGAGAATGAATTTAAAATTGAACCTAAATCTGAAGACATTTCAAATCTTA
GAGCAGCTTAG

Upstream 100 bases:

>100_bases
TAAAAAGTAAATTTTCACTTTTGTTTAATATTCATGACGTTACATAGGGTGGACTTAATATTATTAGTTTGTCATGATAA
ACCTAATAAATTAAGTCTTA

Downstream 100 bases:

>100_bases
TCAGAAACAAAGAAATTTTAAATACTAAGTAAATTAATTCAAACGTAAGCAATATTGATTAGTGAAATACAACCTAAAAA
TAAAAATAACAAAACTAAAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MICGSKKKAYLKSQNLKILGQGKLNGIVKINGAKNSALVLLASSLLTNEKIILENIPYLTDIEKMGNILKNLGVNLIDKN
DQLEIDPTNISIKELPYELVNGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIDEHINGLIALGADIIIEEGIVKAKI
RGNKNKLHGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCHMLNKMGAKIYDSGKETIIIDGVNKLGGC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDL
QAPFTALMTIANGESKITETIFENRMNHIHLLNKMGARIKLNENVAYIKGVKTLNGMDLIGSDLRSSAALIIAGIIAEGT
SNIYGLEHLDRGYENFELKLKKLGIKITREFNKSTFEENEFKIEPKSEDISNLRAA

Sequences:

>Translated_456_residues
MICGSKKKAYLKSQNLKILGQGKLNGIVKINGAKNSALVLLASSLLTNEKIILENIPYLTDIEKMGNILKNLGVNLIDKN
DQLEIDPTNISIKELPYELVNGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIDEHINGLIALGADIIIEEGIVKAKI
RGNKNKLHGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCHMLNKMGAKIYDSGKETIIIDGVNKLGGC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDL
QAPFTALMTIANGESKITETIFENRMNHIHLLNKMGARIKLNENVAYIKGVKTLNGMDLIGSDLRSSAALIIAGIIAEGT
SNIYGLEHLDRGYENFELKLKKLGIKITREFNKSTFEENEFKIEPKSEDISNLRAA
>Mature_456_residues
MICGSKKKAYLKSQNLKILGQGKLNGIVKINGAKNSALVLLASSLLTNEKIILENIPYLTDIEKMGNILKNLGVNLIDKN
DQLEIDPTNISIKELPYELVNGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIDEHINGLIALGADIIIEEGIVKAKI
RGNKNKLHGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCHMLNKMGAKIYDSGKETIIIDGVNKLGGC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDL
QAPFTALMTIANGESKITETIFENRMNHIHLLNKMGARIKLNENVAYIKGVKTLNGMDLIGSDLRSSAALIIAGIIAEGT
SNIYGLEHLDRGYENFELKLKKLGIKITREFNKSTFEENEFKIEPKSEDISNLRAA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=416, Percent_Identity=45.9134615384615, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_PROM9 (Q319I9)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_397892.1
- ProteinModelPortal:   Q319I9
- SMR:   Q319I9
- STRING:   Q319I9
- GeneID:   3766208
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_1396
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   ICGDTDG
- ProtClustDB:   PRK09369
- BioCyc:   PMAR74546:PMT9312_1396-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 49393; Mature: 49393

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICGSKKKAYLKSQNLKILGQGKLNGIVKINGAKNSALVLLASSLLTNEKIILENIPYLT
CCCCCCCCHHEECCCEEEEECCCCCEEEEECCCCCCEEEEEEHHHHCCCEEEECCCCCHH
DIEKMGNILKNLGVNLIDKNDQLEIDPTNISIKELPYELVNGLRASFFCIGALLTKFGEA
HHHHHHHHHHHCCCEEECCCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
QVPLPGGCNIGSRPIDEHINGLIALGADIIIEEGIVKAKIRGNKNKLHGTHIKLKCPSVG
CCCCCCCCCCCCCCHHHHCCEEEEECCHHEEECCEEEEEEECCCCCCCCEEEEEECCCCC
ATETLIMAASLAEGRTTIENAAREPEIQDLCHMLNKMGAKIYDSGKETIIIDGVNKLGGC
CCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKS
CHHCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCEEEEEC
KEIKGVDIETAPFPGFPTDLQAPFTALMTIANGESKITETIFENRMNHIHLLNKMGARIK
CCCCCCEEECCCCCCCCCCCCCCHHHHEEECCCCHHHHHHHHHHCHHHHHHHHHCCCEEE
LNENVAYIKGVKTLNGMDLIGSDLRSSAALIIAGIIAEGTSNIYGLEHLDRGYENFELKL
ECCCEEEEECCCCCCCCHHHHHHHHCCHHEEEEEHHHCCCCCCCCHHHHHCCCCCCEEEE
KKLGIKITREFNKSTFEENEFKIEPKSEDISNLRAA
EECCEEEEEHHCCCCCCCCCEEECCCCCCHHHHCCC
>Mature Secondary Structure
MICGSKKKAYLKSQNLKILGQGKLNGIVKINGAKNSALVLLASSLLTNEKIILENIPYLT
CCCCCCCCHHEECCCEEEEECCCCCEEEEECCCCCCEEEEEEHHHHCCCEEEECCCCCHH
DIEKMGNILKNLGVNLIDKNDQLEIDPTNISIKELPYELVNGLRASFFCIGALLTKFGEA
HHHHHHHHHHHCCCEEECCCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
QVPLPGGCNIGSRPIDEHINGLIALGADIIIEEGIVKAKIRGNKNKLHGTHIKLKCPSVG
CCCCCCCCCCCCCCHHHHCCEEEEECCHHEEECCEEEEEEECCCCCCCCEEEEEECCCCC
ATETLIMAASLAEGRTTIENAAREPEIQDLCHMLNKMGAKIYDSGKETIIIDGVNKLGGC
CCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKS
CHHCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCEEEEEC
KEIKGVDIETAPFPGFPTDLQAPFTALMTIANGESKITETIFENRMNHIHLLNKMGARIK
CCCCCCEEECCCCCCCCCCCCCCHHHHEEECCCCHHHHHHHHHHCHHHHHHHHHCCCEEE
LNENVAYIKGVKTLNGMDLIGSDLRSSAALIIAGIIAEGTSNIYGLEHLDRGYENFELKL
ECCCEEEEECCCCCCCCHHHHHHHHCCHHEEEEEHHHCCCCCCCCHHHHHCCCCCCEEEE
KKLGIKITREFNKSTFEENEFKIEPKSEDISNLRAA
EECCEEEEEHHCCCCCCCCCEEECCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA