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The map label for this gene is neuA [H]

Identifier: 78779733

GI number: 78779733

Start: 1264961

End: 1265644

Strand: Direct

Name: neuA [H]

Synonym: PMT9312_1349

Alternate gene names: 78779733

Gene position: 1264961-1265644 (Clockwise)

Preceding gene: 78779732

Following gene: 78779734

Centisome position: 74.01

GC content: 28.22

Gene sequence:

>684_bases
ATGAAGTTTGTTGCAATTCTTTTGGCCAGAGGAGGATCCAAAGGGATTCCAAAGAAAAATCTTTTAAAAATAAATAAAAT
TCCTTTAATTAGTTTTACTATAAGACAGTGTTTTAGTGCAGGTATAGAAGAAATTTATACAAGTTCTGATGATGATGAAA
TCTTATCTGTTGCGAGAGATGAAGGTTCTAAATTAATTAAAAGGCCCTTAGATATTGCCCATGATTGTTCTACATCAGAA
TCGGCTTGGTTACATGCTATTGATAATATTGACAATTTAGATGATAGCAATGACTGGATATTTGCCCCTCAATTAACATC
TCCAATTAGAGAAACATTTGACATTAAGAATGGACTAGAAATTGCAAGCAGTAATAAATATGATTCAATATTTTCGGCTG
TAGAATTAAATGACTTTTTAATCTGGAAAAATGAAAATAATAAATTGGAGCCAATAAATTATGACTTTCAAAAACGACTA
AGAAGGCAAGATATTAAGGTAAATAATTATCTAGAAAATGGCTCTTTTTATTTATTTAAACCTTGTGGCATAAAAAAATT
TAATAATAGGCTTTATGGAAGAATAGGGATATGTAAAATGGACAAATTAAAAATGTTCCAAATAGATCACTATAGTGATA
TTTTTATTGTAGAAAAAATCTTGCAGAAACTCAATATCAAATAA

Upstream 100 bases:

>100_bases
AGAATAATTATAATGGTGTTATTACTTTCCAAGCATATAGAGACACAGAAGGTATTTCAATTTTCAAAAAGCAATATCAA
TATTTCTTAGACTTAAAAAT

Downstream 100 bases:

>100_bases
ATGAGTATGTTTTCTGTAAAAAATAAACGTGTATTAGTCGTGGGGGCCTCTAGGGGGATTGGTCTTGAAATATCAATCAA
ATTGAAAGAGGGAAAAGCTG

Product: putative acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKFVAILLARGGSKGIPKKNLLKINKIPLISFTIRQCFSAGIEEIYTSSDDDEILSVARDEGSKLIKRPLDIAHDCSTSE
SAWLHAIDNIDNLDDSNDWIFAPQLTSPIRETFDIKNGLEIASSNKYDSIFSAVELNDFLIWKNENNKLEPINYDFQKRL
RRQDIKVNNYLENGSFYLFKPCGIKKFNNRLYGRIGICKMDKLKMFQIDHYSDIFIVEKILQKLNIK

Sequences:

>Translated_227_residues
MKFVAILLARGGSKGIPKKNLLKINKIPLISFTIRQCFSAGIEEIYTSSDDDEILSVARDEGSKLIKRPLDIAHDCSTSE
SAWLHAIDNIDNLDDSNDWIFAPQLTSPIRETFDIKNGLEIASSNKYDSIFSAVELNDFLIWKNENNKLEPINYDFQKRL
RRQDIKVNNYLENGSFYLFKPCGIKKFNNRLYGRIGICKMDKLKMFQIDHYSDIFIVEKILQKLNIK
>Mature_227_residues
MKFVAILLARGGSKGIPKKNLLKINKIPLISFTIRQCFSAGIEEIYTSSDDDEILSVARDEGSKLIKRPLDIAHDCSTSE
SAWLHAIDNIDNLDDSNDWIFAPQLTSPIRETFDIKNGLEIASSNKYDSIFSAVELNDFLIWKNENNKLEPINYDFQKRL
RRQDIKVNNYLENGSFYLFKPCGIKKFNNRLYGRIGICKMDKLKMFQIDHYSDIFIVEKILQKLNIK

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=182, Percent_Identity=37.3626373626374, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 26219; Mature: 26219

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVAILLARGGSKGIPKKNLLKINKIPLISFTIRQCFSAGIEEIYTSSDDDEILSVARD
CCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EGSKLIKRPLDIAHDCSTSESAWLHAIDNIDNLDDSNDWIFAPQLTSPIRETFDIKNGLE
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCE
IASSNKYDSIFSAVELNDFLIWKNENNKLEPINYDFQKRLRRQDIKVNNYLENGSFYLFK
ECCCCCHHHHHHHEECCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHEEEECCCEEEEC
PCGIKKFNNRLYGRIGICKMDKLKMFQIDHYSDIFIVEKILQKLNIK
CCCCHHHCCCEEEEEEEEEECCEEEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFVAILLARGGSKGIPKKNLLKINKIPLISFTIRQCFSAGIEEIYTSSDDDEILSVARD
CCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EGSKLIKRPLDIAHDCSTSESAWLHAIDNIDNLDDSNDWIFAPQLTSPIRETFDIKNGLE
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCE
IASSNKYDSIFSAVELNDFLIWKNENNKLEPINYDFQKRLRRQDIKVNNYLENGSFYLFK
ECCCCCHHHHHHHEECCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHEEEECCCEEEEC
PCGIKKFNNRLYGRIGICKMDKLKMFQIDHYSDIFIVEKILQKLNIK
CCCCHHHCCCEEEEEEEEEECCEEEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]