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The map label for this gene is tpiA

Identifier: 78779355

GI number: 78779355

Start: 905451

End: 906176

Strand: Reverse

Name: tpiA

Synonym: PMT9312_0971

Alternate gene names: 78779355

Gene position: 906176-905451 (Counterclockwise)

Preceding gene: 78779356

Following gene: 78779354

Centisome position: 53.02

GC content: 33.75

Gene sequence:

>726_bases
TTGAGAAAATCTGTTATTGCTGGTAATTGGAAAATGCATATGACTTGTGCTGAAGCGAAGTCTTATTTAGAAGAGTTTAT
ACCTTTAATAAAAAACATCAGAGATGATCGTAAAGTTGTTATTGCGCCACCTTTTACAGCTATTTCAACCTTTTCTAAGC
ATTCTGATTTTGATTATTTAGATATTTCTAGTCAAAATATTCATTGGGAAGATGAAGGAGCATTTACTGCGGAAATATCT
CCAAAAATGCTGATTGAACATGGAGTCTCATATGCAATAGTTGGTCACAGTGAACCAAGAAAATATTTTAGTGAAAGTGA
TGAACAAATTAATAAAAGAGCAGTTTTTGCTCAATGTAGTGGACTTACTCCCATAGTTTGTGTTGGAGAAACACTAGAAC
AAAGAGAGAGAGGAGAGGCTGATAGAGTTATCACTAGACAGGTAGAACAAGGGCTAGAAAATACAGATCCATCAAATTTA
ATTGTTGCCTATGAACCAATTTGGGCTATTGGGACAGGTAAAACATGTGAGGCTAAAGACGCTAATAATATATGTTCTTT
GATTCGAAAATTAATAGGTTTCGATGATGTGATTATTCAATATGGAGGATCAGTTAAACCTAATAATATTGACGAAATAA
TGTCGATGAGTGATATAGATGGAGTCTTAGTTGGAGGGGCTTCATTAGATCCAAATAGTTTTGCCAGAATTGCAAATTAT
CAATAA

Upstream 100 bases:

>100_bases
AAGGGAGATAAAGTTATATTTCTAAAAAATGAATTAATTTTTGAATAGTTGGCTTATTCAACTCAATTTATATTAATATA
ATTTTCTTGGAGATAGTATT

Downstream 100 bases:

>100_bases
GCAAAATCCATGGCCAAAAGGCTGGAGACAAAAAACTTCAATTATGGGAGTTATTAATTTAACTCCTGATTCATTTAGTG
ATGGTGGAGATTTAAATTCT

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRKSVIAGNWKMHMTCAEAKSYLEEFIPLIKNIRDDRKVVIAPPFTAISTFSKHSDFDYLDISSQNIHWEDEGAFTAEIS
PKMLIEHGVSYAIVGHSEPRKYFSESDEQINKRAVFAQCSGLTPIVCVGETLEQRERGEADRVITRQVEQGLENTDPSNL
IVAYEPIWAIGTGKTCEAKDANNICSLIRKLIGFDDVIIQYGGSVKPNNIDEIMSMSDIDGVLVGGASLDPNSFARIANY
Q

Sequences:

>Translated_241_residues
MRKSVIAGNWKMHMTCAEAKSYLEEFIPLIKNIRDDRKVVIAPPFTAISTFSKHSDFDYLDISSQNIHWEDEGAFTAEIS
PKMLIEHGVSYAIVGHSEPRKYFSESDEQINKRAVFAQCSGLTPIVCVGETLEQRERGEADRVITRQVEQGLENTDPSNL
IVAYEPIWAIGTGKTCEAKDANNICSLIRKLIGFDDVIIQYGGSVKPNNIDEIMSMSDIDGVLVGGASLDPNSFARIANY
Q
>Mature_241_residues
MRKSVIAGNWKMHMTCAEAKSYLEEFIPLIKNIRDDRKVVIAPPFTAISTFSKHSDFDYLDISSQNIHWEDEGAFTAEIS
PKMLIEHGVSYAIVGHSEPRKYFSESDEQINKRAVFAQCSGLTPIVCVGETLEQRERGEADRVITRQVEQGLENTDPSNL
IVAYEPIWAIGTGKTCEAKDANNICSLIRKLIGFDDVIIQYGGSVKPNNIDEIMSMSDIDGVLVGGASLDPNSFARIANY
Q

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI226529917, Length=248, Percent_Identity=38.7096774193548, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI4507645, Length=250, Percent_Identity=38.4, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1790353, Length=252, Percent_Identity=38.0952380952381, Blast_Score=168, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17536593, Length=246, Percent_Identity=37.8048780487805, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6320255, Length=246, Percent_Identity=35.7723577235772, Blast_Score=142, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28572008, Length=239, Percent_Identity=39.7489539748954, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI28572006, Length=239, Percent_Identity=39.7489539748954, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI28572004, Length=239, Percent_Identity=39.7489539748954, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26809; Mature: 26809

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSVIAGNWKMHMTCAEAKSYLEEFIPLIKNIRDDRKVVIAPPFTAISTFSKHSDFDYL
CCCCEEECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEE
DISSQNIHWEDEGAFTAEISPKMLIEHGVSYAIVGHSEPRKYFSESDEQINKRAVFAQCS
ECCCCCCEECCCCCEEEECCHHHHHHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHC
GLTPIVCVGETLEQRERGEADRVITRQVEQGLENTDPSNLIVAYEPIWAIGTGKTCEAKD
CCCEEEECCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCCCCC
ANNICSLIRKLIGFDDVIIQYGGSVKPNNIDEIMSMSDIDGVLVGGASLDPNSFARIANY
HHHHHHHHHHHHCCCCEEHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHCCC
Q
C
>Mature Secondary Structure
MRKSVIAGNWKMHMTCAEAKSYLEEFIPLIKNIRDDRKVVIAPPFTAISTFSKHSDFDYL
CCCCEEECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEE
DISSQNIHWEDEGAFTAEISPKMLIEHGVSYAIVGHSEPRKYFSESDEQINKRAVFAQCS
ECCCCCCEECCCCCEEEECCHHHHHHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHC
GLTPIVCVGETLEQRERGEADRVITRQVEQGLENTDPSNLIVAYEPIWAIGTGKTCEAKD
CCCEEEECCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCCCCC
ANNICSLIRKLIGFDDVIIQYGGSVKPNNIDEIMSMSDIDGVLVGGASLDPNSFARIANY
HHHHHHHHHHHHCCCCEEHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA