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The map label for this gene is cobU [H]

Identifier: 78779322

GI number: 78779322

Start: 872951

End: 873511

Strand: Direct

Name: cobU [H]

Synonym: PMT9312_0938

Alternate gene names: 78779322

Gene position: 872951-873511 (Clockwise)

Preceding gene: 78779321

Following gene: 78779323

Centisome position: 51.07

GC content: 28.34

Gene sequence:

>561_bases
ATGAATTCCAAGGATTTAAATATTAAAGATTATTTATCTCATATTATTTTTATTACAGGAGGAACAAAGAGTGGTAAAAG
TGAATTCGCAGAGCATCTAGCAAAGGAAGTAAAAAAATTATCATATGTTGCCTTATCTGAAAACAATATTGATGATAAAG
AATGGCAAGAAAAAATTAATATACATAGAAACAGAAGGCCGAAATATTGGAAGTTAATTGAAACCACAGATCTATTAAAT
ACATTAAGCAAAGAAGATGGTCCATTATTAATAGACTCGATTGGTGGATTTGTTATGGAAAATATTGGAAAAGAACATAA
TGAATGGTCAACAAAGATGTATTCTCTTATAAATCTTTTAATAAAAAGAAAAAGCATAACATTTATTGTTGGAGAACAAG
TAGGTTGGAGTTTGGTCTCTGAATATAAAATTGGTAATACTTATATTGAAAGAATCGGCGAACTTCAAAAGAGAATAACC
AAAATATCCAAAGATAATTGGCTGGCAATAAATGGCAGAGCAATCAAAATAGATGATATAAGTTTAGAAATACCTGCTTA
A

Upstream 100 bases:

>100_bases
GAGAGTTCAACAGCTACTTATATAGTTATTGCATTATTAATTGCTGCCACGATTATTCCTTTAGCAACATGGTGGTATTT
CTCTAAATAATAGAGAATTT

Downstream 100 bases:

>100_bases
AATTGGAAGTCACTCTATTTGAACCTAGAATCCCTCAAAATACTGGTAATATTGCCAGATCATGTGCTGCATTTAATATA
CCTTTAAATCTTATAGAGCC

Product: adenosylcobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNSKDLNIKDYLSHIIFITGGTKSGKSEFAEHLAKEVKKLSYVALSENNIDDKEWQEKINIHRNRRPKYWKLIETTDLLN
TLSKEDGPLLIDSIGGFVMENIGKEHNEWSTKMYSLINLLIKRKSITFIVGEQVGWSLVSEYKIGNTYIERIGELQKRIT
KISKDNWLAINGRAIKIDDISLEIPA

Sequences:

>Translated_186_residues
MNSKDLNIKDYLSHIIFITGGTKSGKSEFAEHLAKEVKKLSYVALSENNIDDKEWQEKINIHRNRRPKYWKLIETTDLLN
TLSKEDGPLLIDSIGGFVMENIGKEHNEWSTKMYSLINLLIKRKSITFIVGEQVGWSLVSEYKIGNTYIERIGELQKRIT
KISKDNWLAINGRAIKIDDISLEIPA
>Mature_186_residues
MNSKDLNIKDYLSHIIFITGGTKSGKSEFAEHLAKEVKKLSYVALSENNIDDKEWQEKINIHRNRRPKYWKLIETTDLLN
TLSKEDGPLLIDSIGGFVMENIGKEHNEWSTKMYSLINLLIKRKSITFIVGEQVGWSLVSEYKIGNTYIERIGELQKRIT
KISKDNWLAINGRAIKIDDISLEIPA

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=25.9668508287293, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21408; Mature: 21408

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKDLNIKDYLSHIIFITGGTKSGKSEFAEHLAKEVKKLSYVALSENNIDDKEWQEKIN
CCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
IHRNRRPKYWKLIETTDLLNTLSKEDGPLLIDSIGGFVMENIGKEHNEWSTKMYSLINLL
HCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IKRKSITFIVGEQVGWSLVSEYKIGNTYIERIGELQKRITKISKDNWLAINGRAIKIDDI
HHHCCEEEEECCHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECE
SLEIPA
EEEECC
>Mature Secondary Structure
MNSKDLNIKDYLSHIIFITGGTKSGKSEFAEHLAKEVKKLSYVALSENNIDDKEWQEKIN
CCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
IHRNRRPKYWKLIETTDLLNTLSKEDGPLLIDSIGGFVMENIGKEHNEWSTKMYSLINLL
HCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IKRKSITFIVGEQVGWSLVSEYKIGNTYIERIGELQKRITKISKDNWLAINGRAIKIDDI
HHHCCEEEEECCHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECE
SLEIPA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]