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The map label for this gene is pgi

Identifier: 78779294

GI number: 78779294

Start: 841041

End: 842624

Strand: Direct

Name: pgi

Synonym: PMT9312_0910

Alternate gene names: 78779294

Gene position: 841041-842624 (Clockwise)

Preceding gene: 78779292

Following gene: 78779296

Centisome position: 49.21

GC content: 30.05

Gene sequence:

>1584_bases
ATGAATGAAGAATTAAACTCATGGGATAAATTTTGTAATTATCTTTGGTTTGATAAAAAATTAAATATTTGGTTAGATAT
AAGCAAAATTATTTTTACAAATGACGACATTGTCACTTTAGAAGAGAAATTTACAGATGTTTTGTCATCAATAAAAGAAT
TAGAAAATGGTGCAATCTCAAATATTGATGAAAATAGACAAGTTGGACATTATTGGCTTAGAAATCCATCAATTTCTCCA
TCTTCCAATATAGGAGAGGAGATTAGTGCAGATATAAATGAAATCTCTGAATTTGGCAAACAAATTTTAAATGGAAATAT
TAAGAATAAGAATAATCAGAAATATACTGATGTTCTATGGATAGGAATTGGTGGAAGTGGATTAGGCCCATTACTTATTA
CAGAGTCACTGCAGAAGTGCTCTAAAGGATTAAATTTTTCTTATATCGATAATGTTGATCCTTTTTTAATTAGCGAAAAG
TTAGAAGAGTTAGCTGAAAAATTATCCACAACATTATTTGTAGTAGTAAGCAAATCGGGTGGTACGCCTGAACCTAGAAT
TGCTATGGAAATTATTAAGAGTCATTGTGAAAACAATTCACTTGAATGGAATTCTAATGCTATAGCTATAACTATGAAAG
ATAGTAAGTTATTTAATAAAGCCATTTCTGAAAATTGGTTAAAAATATTCAATTTACAAGATTGGGTTGGAGGAAGAACT
AGTATTACTAGCTCTGTAGGATTACTTCCATTAGCTCTTATTAATGAAAATATATTTGAATTTATTAGAGGTGCATCATT
AATGGATGAGGCCACACGTACTAGTGATTTTAAAAATAATCCCGCAGCATTATTATCATCTGCATGGTATTTAACTGGAG
ATGGCGTTGGAAAGAGAGATATGGTTGTTTTACCTTATAGAGATAGGTTACAGGTATTTAGTAAATATCTTCAGCAATTA
GTAATGGAGTCTTTAGGAAAGAAATTTAATAGGAATGGTGAAGTAGTTAATCAAGGGATATCCGTTTTTGGTAATAAAGG
ATCTACAGATCAACATGCTTATGTTCAGCAACTGAGAGATGGTATTGATAACTTCTTTTGTATTTTTATTGAATTATTAG
ATTCTCCATCGACTAATATTTTTGATGGAAAAGAGAATCCTAAAGAATATCTTTCTGGTTTTTTGCAGGGAACTAGATCC
GCACTTTCTAGTGAAAACAGACAAAGTATCACTATCACATTAGAAAAATTAAATTGTTTTTCACTAGGTGCCTTAATCGC
TTTATTTGAGAGATCTGTATCTTTCTACGCTGAATTAGTAAATATAAATGCCTATGATCAACCTGGAGTTGAAGCCGGAA
AGAAAGCAGCTGCAAATATTATTGACTATCAACAAAAAGTAAGTAATTTATTAGAGAAAGGAGGCGAATATTCTATCAAT
GAAATAACATCATTAATTGATAATTCAGTTAGTGAACCTATATTTTTCATACTTCGTGAAATGTGTTTCGGTAATGAAGA
TTATTTAGTTAAGGGCGATTGGTCAAATCCAAATTCATTAGTTATTCAAAAAAGAAATTCTTAA

Upstream 100 bases:

>100_bases
TAAATTTAAAGATATAAATTTAAACAAATTTAAAAGAATTAATTCTATGTACTATTCGTAAAGATATAATTAAATCATAA
ATAAAGGAAAAATATATAAA

Downstream 100 bases:

>100_bases
ACAACAATATTCATAATTTTTCCTTTAACAATAATTATTTTTCTTATTTCCTTATCTTGAGTCCATTTTAATATATTGGG
TCTTTTAAGAGTTAATTCCT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MNEELNSWDKFCNYLWFDKKLNIWLDISKIIFTNDDIVTLEEKFTDVLSSIKELENGAISNIDENRQVGHYWLRNPSISP
SSNIGEEISADINEISEFGKQILNGNIKNKNNQKYTDVLWIGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEK
LEELAEKLSTTLFVVVSKSGGTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKDSKLFNKAISENWLKIFNLQDWVGGRT
SITSSVGLLPLALINENIFEFIRGASLMDEATRTSDFKNNPAALLSSAWYLTGDGVGKRDMVVLPYRDRLQVFSKYLQQL
VMESLGKKFNRNGEVVNQGISVFGNKGSTDQHAYVQQLRDGIDNFFCIFIELLDSPSTNIFDGKENPKEYLSGFLQGTRS
ALSSENRQSITITLEKLNCFSLGALIALFERSVSFYAELVNINAYDQPGVEAGKKAAANIIDYQQKVSNLLEKGGEYSIN
EITSLIDNSVSEPIFFILREMCFGNEDYLVKGDWSNPNSLVIQKRNS

Sequences:

>Translated_527_residues
MNEELNSWDKFCNYLWFDKKLNIWLDISKIIFTNDDIVTLEEKFTDVLSSIKELENGAISNIDENRQVGHYWLRNPSISP
SSNIGEEISADINEISEFGKQILNGNIKNKNNQKYTDVLWIGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEK
LEELAEKLSTTLFVVVSKSGGTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKDSKLFNKAISENWLKIFNLQDWVGGRT
SITSSVGLLPLALINENIFEFIRGASLMDEATRTSDFKNNPAALLSSAWYLTGDGVGKRDMVVLPYRDRLQVFSKYLQQL
VMESLGKKFNRNGEVVNQGISVFGNKGSTDQHAYVQQLRDGIDNFFCIFIELLDSPSTNIFDGKENPKEYLSGFLQGTRS
ALSSENRQSITITLEKLNCFSLGALIALFERSVSFYAELVNINAYDQPGVEAGKKAAANIIDYQQKVSNLLEKGGEYSIN
EITSLIDNSVSEPIFFILREMCFGNEDYLVKGDWSNPNSLVIQKRNS
>Mature_527_residues
MNEELNSWDKFCNYLWFDKKLNIWLDISKIIFTNDDIVTLEEKFTDVLSSIKELENGAISNIDENRQVGHYWLRNPSISP
SSNIGEEISADINEISEFGKQILNGNIKNKNNQKYTDVLWIGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEK
LEELAEKLSTTLFVVVSKSGGTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKDSKLFNKAISENWLKIFNLQDWVGGRT
SITSSVGLLPLALINENIFEFIRGASLMDEATRTSDFKNNPAALLSSAWYLTGDGVGKRDMVVLPYRDRLQVFSKYLQQL
VMESLGKKFNRNGEVVNQGISVFGNKGSTDQHAYVQQLRDGIDNFFCIFIELLDSPSTNIFDGKENPKEYLSGFLQGTRS
ALSSENRQSITITLEKLNCFSLGALIALFERSVSFYAELVNINAYDQPGVEAGKKAAANIIDYQQKVSNLLEKGGEYSIN
EITSLIDNSVSEPIFFILREMCFGNEDYLVKGDWSNPNSLVIQKRNS

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=491, Percent_Identity=30.142566191446, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI296080693, Length=487, Percent_Identity=27.9260780287474, Blast_Score=140, Evalue=4e-33,
Organism=Escherichia coli, GI1790457, Length=504, Percent_Identity=31.1507936507937, Blast_Score=186, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71996703, Length=440, Percent_Identity=30.4545454545455, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71996708, Length=440, Percent_Identity=30.4545454545455, Blast_Score=161, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6319673, Length=469, Percent_Identity=29.8507462686567, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24651916, Length=493, Percent_Identity=30.4259634888438, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24651914, Length=493, Percent_Identity=30.4259634888438, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17737445, Length=493, Percent_Identity=30.4259634888438, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59162; Mature: 59162

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEELNSWDKFCNYLWFDKKLNIWLDISKIIFTNDDIVTLEEKFTDVLSSIKELENGAIS
CCCCHHHHHHHHHHEEECCCEEEEEEEEEEEEECCCEEEHHHHHHHHHHHHHHHCCCCCC
NIDENRQVGHYWLRNPSISPSSNIGEEISADINEISEFGKQILNGNIKNKNNQKYTDVLW
CCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEKLEELAEKLSTTLFVVVSKSG
EEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCC
GTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKDSKLFNKAISENWLKIFNLQDWVGGRT
CCCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHCCCCH
SITSSVGLLPLALINENIFEFIRGASLMDEATRTSDFKNNPAALLSSAWYLTGDGVGKRD
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCC
MVVLPYRDRLQVFSKYLQQLVMESLGKKFNRNGEVVNQGISVFGNKGSTDQHAYVQQLRD
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCHHHHHHHHHHH
GIDNFFCIFIELLDSPSTNIFDGKENPKEYLSGFLQGTRSALSSENRQSITITLEKLNCF
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHH
SLGALIALFERSVSFYAELVNINAYDQPGVEAGKKAAANIIDYQQKVSNLLEKGGEYSIN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EITSLIDNSVSEPIFFILREMCFGNEDYLVKGDWSNPNSLVIQKRNS
HHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCC
>Mature Secondary Structure
MNEELNSWDKFCNYLWFDKKLNIWLDISKIIFTNDDIVTLEEKFTDVLSSIKELENGAIS
CCCCHHHHHHHHHHEEECCCEEEEEEEEEEEEECCCEEEHHHHHHHHHHHHHHHCCCCCC
NIDENRQVGHYWLRNPSISPSSNIGEEISADINEISEFGKQILNGNIKNKNNQKYTDVLW
CCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEKLEELAEKLSTTLFVVVSKSG
EEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCC
GTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKDSKLFNKAISENWLKIFNLQDWVGGRT
CCCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHCCCCH
SITSSVGLLPLALINENIFEFIRGASLMDEATRTSDFKNNPAALLSSAWYLTGDGVGKRD
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCC
MVVLPYRDRLQVFSKYLQQLVMESLGKKFNRNGEVVNQGISVFGNKGSTDQHAYVQQLRD
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCHHHHHHHHHHH
GIDNFFCIFIELLDSPSTNIFDGKENPKEYLSGFLQGTRSALSSENRQSITITLEKLNCF
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHH
SLGALIALFERSVSFYAELVNINAYDQPGVEAGKKAAANIIDYQQKVSNLLEKGGEYSIN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EITSLIDNSVSEPIFFILREMCFGNEDYLVKGDWSNPNSLVIQKRNS
HHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA