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The map label for this gene is pip [H]

Identifier: 78778745

GI number: 78778745

Start: 341259

End: 342209

Strand: Direct

Name: pip [H]

Synonym: PMT9312_0360

Alternate gene names: 78778745

Gene position: 341259-342209 (Clockwise)

Preceding gene: 78778743

Following gene: 78778746

Centisome position: 19.97

GC content: 29.44

Gene sequence:

>951_bases
ATGAAAGATCAAGTCTTGTTTCCGAAAATTGAATTACGTGAAAAGGGTTTTTTACAAGTTAGTGATATTCATACTATTTA
TTGGGAAAGATCTGGCAATCCAAATGGAAAGAAAATACTGGTAATTCATGGAGGTCCAGGAGGAGGAAGTCAACCAAGAT
ATAGAAGATACTTTGATCCAGATAAATTCGATATTATTCAATTTGACCAAAGAGGGTGCGGTTCCTCAACTCCTTTCTCC
GAATTAAAAGAAAATACGACTAATCATTTAGTTGATGATATTGAGAAATTAAGAATTTTATTTAAAATAGATAGTTGGAA
TTTGTTTGGTGGATCTTGGGGCTCAACACTTTCACTTATATATGCAATTAAAAATCCCAAAAGAGTTATGAGCTTAACTT
TGCGAGGAATATTTTTATGTAGAAAGTTTGAATTATTATGGTTCTATCAATATGGTGCAAGTGAGATATTCCCCGATGAA
TTTGAAGAATATATTTCTTTAATACCAAAAAAAGAAAGAAATGATTTGATAAGTTCTTTTTATAAATATCTAACATCTTC
AGATGTGAAGCTTAGATCAAGAGCAGCAGCAGCTTGGACAAAATGGGAACTTTCAACTAGTCATTTAATAAATAAAAAAT
TTGATTTTGGTAAGTCCCAAGTTAATTCTTTTTCAGATGCCTTTGCGAGGATCGAATGTCATTATTTTATTAATAATATT
TTCTTAGAAGATGATTTTATTTTGAAAAATATAAAATCAATAGAATCGATACCAACAAAAATAATTCAAGGTAGATATGA
CGTCGTATGTCCTGTTAGGAGTGCTTGGGATTTAAATAAAAAATTAAAGAATTCTGAATTAATTATTGTTAATGATGCTG
GTCATTCAATGAGTGAAAAAGGTATTAGTATCGAATTAATAAAAGCTGTAAAAGGAATTGAAAATCTCTAA

Upstream 100 bases:

>100_bases
GGACTGCTCAAACAGTCCTTTTTTATGTTTAAGAAATTGATTTTAAACTGAAGTCTTTGTGGATACTATAGATTTATAAA
GGGATTAAAAATATTTCAAA

Downstream 100 bases:

>100_bases
TAAAAAGAATATTTTTTTAAAAATTAAAGGCCATTATCTTCAATATTTTGTGCAATACTCATAAGAAGTTCGACGATATC
AGAATCTTCGCATTGAGTAT

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKDQVLFPKIELREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDPDKFDIIQFDQRGCGSSTPFS
ELKENTTNHLVDDIEKLRILFKIDSWNLFGGSWGSTLSLIYAIKNPKRVMSLTLRGIFLCRKFELLWFYQYGASEIFPDE
FEEYISLIPKKERNDLISSFYKYLTSSDVKLRSRAAAAWTKWELSTSHLINKKFDFGKSQVNSFSDAFARIECHYFINNI
FLEDDFILKNIKSIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEKGISIELIKAVKGIENL

Sequences:

>Translated_316_residues
MKDQVLFPKIELREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDPDKFDIIQFDQRGCGSSTPFS
ELKENTTNHLVDDIEKLRILFKIDSWNLFGGSWGSTLSLIYAIKNPKRVMSLTLRGIFLCRKFELLWFYQYGASEIFPDE
FEEYISLIPKKERNDLISSFYKYLTSSDVKLRSRAAAAWTKWELSTSHLINKKFDFGKSQVNSFSDAFARIECHYFINNI
FLEDDFILKNIKSIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEKGISIELIKAVKGIENL
>Mature_316_residues
MKDQVLFPKIELREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDPDKFDIIQFDQRGCGSSTPFS
ELKENTTNHLVDDIEKLRILFKIDSWNLFGGSWGSTLSLIYAIKNPKRVMSLTLRGIFLCRKFELLWFYQYGASEIFPDE
FEEYISLIPKKERNDLISSFYKYLTSSDVKLRSRAAAAWTKWELSTSHLINKKFDFGKSQVNSFSDAFARIECHYFINNI
FLEDDFILKNIKSIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEKGISIELIKAVKGIENL

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36492; Mature: 36492

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDQVLFPKIELREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDP
CCCCEECCCEEECCCCCEEEECEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
DKFDIIQFDQRGCGSSTPFSELKENTTNHLVDDIEKLRILFKIDSWNLFGGSWGSTLSLI
CCEEEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHEEEEEEECCCEECCCCCCCCEEEE
YAIKNPKRVMSLTLRGIFLCRKFELLWFYQYGASEIFPDEFEEYISLIPKKERNDLISSF
EEECCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
YKYLTSSDVKLRSRAAAAWTKWELSTSHLINKKFDFGKSQVNSFSDAFARIECHYFINNI
HHHHCCCCCHHHHHHHHHEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEEEE
FLEDDFILKNIKSIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEK
EECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCHHHHCCCCCEEEEECCCCCCHHC
GISIELIKAVKGIENL
CCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKDQVLFPKIELREKGFLQVSDIHTIYWERSGNPNGKKILVIHGGPGGGSQPRYRRYFDP
CCCCEECCCEEECCCCCEEEECEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
DKFDIIQFDQRGCGSSTPFSELKENTTNHLVDDIEKLRILFKIDSWNLFGGSWGSTLSLI
CCEEEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHEEEEEEECCCEECCCCCCCCEEEE
YAIKNPKRVMSLTLRGIFLCRKFELLWFYQYGASEIFPDEFEEYISLIPKKERNDLISSF
EEECCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
YKYLTSSDVKLRSRAAAAWTKWELSTSHLINKKFDFGKSQVNSFSDAFARIECHYFINNI
HHHHCCCCCHHHHHHHHHEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEEEE
FLEDDFILKNIKSIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIVNDAGHSMSEK
EECCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCHHHHCCCCCEEEEECCCCCCHHC
GISIELIKAVKGIENL
CCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA