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The map label for this gene is cmpR [H]

Identifier: 78484770

GI number: 78484770

Start: 476871

End: 477815

Strand: Reverse

Name: cmpR [H]

Synonym: Tcr_0425

Alternate gene names: 78484770

Gene position: 477815-476871 (Counterclockwise)

Preceding gene: 78484771

Following gene: 78484769

Centisome position: 19.68

GC content: 42.01

Gene sequence:

>945_bases
ATGCCTGAAAAAATTTCCATCCTGGCTCGAAACGCCACATTAAGACAACTTCAAGTCTTTGAAAGCATTGCCCGACATAA
CAGCTTCTCCAAAGCGGCCGAAGAACTTCACCTGACTCAACCAACGGTTTCCATGCAGGTTAAGAAACTGGCCGAAATTT
TGGAAAGTCCTTTATTTGAACAAATTGGTCGTAAAGCCCATTTAACAGAAGCCGGTAAAGCACTCTACGATTCCGCCAAT
AATATCTTGCAGCAACTGTCGATTGCTGAACAGAAAATCAATCACCTCAAAGGGTTTTCTGGGGGCAGCGTCAAATTTAC
GGTGATCTCAACGGCGCAATATTTTGTGCCTAAAGTCATTCAAAATTTCACGCAATCCTACCCAGACGTCACCATCATCA
TGCGGGTTGGTAACAAAGAGAGCTTGATCGAACGTATTAACAATAACAAGGACGACTTTTATTTACTCGGACAACCGCCA
GAAGACTTAAATGTGGAATCTTCTCAGCTGTCCGTCAACCCATTGGCTTTTTTGGCCAACAGTGATCATCCTCTGGTTGG
AAAGCAACTCTCAATTCAAGACCTGGTAAATGAACCTTTTTTAATGCGCGAAACGGGTTCAGGTATTCGGGCTCAAATTG
AAAAGGTCTTTGGAGAATTTGAATTTCAACCCAATATTAAAATGGTGCTGGGTGGCAATGAACCTATTCGACTCGGCTTA
CTACAAAATCTTGGAATCACGGTTGCATCGGTTCCCACTTTAATGGAAGAAATTAATCAAGGAAAAATCAGCATCCTCAA
TGTCAAAGGATTTCCAATCAATCGTCATTGGTATCTGGCTTATCCAAAAGGCAAAGTACTGTCTATTGCGGCAGAAAAAC
TCATTGAGTTACTGAAAATCGAAGGCGAAAAACTCAGCGAACAGGCGTTTAACCAATTTCGCTAA

Upstream 100 bases:

>100_bases
TAAGGTACTCATGCCACCGGCTGTTGCCTTTTTAGAGTTTCTAAAATCGGTCGACATTAACAAATTGCTGGCCATGTCGG
ACACGCGCTAAGGAATCATT

Downstream 100 bases:

>100_bases
CCCAACCTTGCAGATTATTATGCATCATTTAAATCATTCCTCAATAGAATAGATAATAATCTATCAGTTTAATCAAAATT
ATTGATTTGAAGTTATCTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPEKISILARNATLRQLQVFESIARHNSFSKAAEELHLTQPTVSMQVKKLAEILESPLFEQIGRKAHLTEAGKALYDSAN
NILQQLSIAEQKINHLKGFSGGSVKFTVISTAQYFVPKVIQNFTQSYPDVTIIMRVGNKESLIERINNNKDDFYLLGQPP
EDLNVESSQLSVNPLAFLANSDHPLVGKQLSIQDLVNEPFLMRETGSGIRAQIEKVFGEFEFQPNIKMVLGGNEPIRLGL
LQNLGITVASVPTLMEEINQGKISILNVKGFPINRHWYLAYPKGKVLSIAAEKLIELLKIEGEKLSEQAFNQFR

Sequences:

>Translated_314_residues
MPEKISILARNATLRQLQVFESIARHNSFSKAAEELHLTQPTVSMQVKKLAEILESPLFEQIGRKAHLTEAGKALYDSAN
NILQQLSIAEQKINHLKGFSGGSVKFTVISTAQYFVPKVIQNFTQSYPDVTIIMRVGNKESLIERINNNKDDFYLLGQPP
EDLNVESSQLSVNPLAFLANSDHPLVGKQLSIQDLVNEPFLMRETGSGIRAQIEKVFGEFEFQPNIKMVLGGNEPIRLGL
LQNLGITVASVPTLMEEINQGKISILNVKGFPINRHWYLAYPKGKVLSIAAEKLIELLKIEGEKLSEQAFNQFR
>Mature_313_residues
PEKISILARNATLRQLQVFESIARHNSFSKAAEELHLTQPTVSMQVKKLAEILESPLFEQIGRKAHLTEAGKALYDSANN
ILQQLSIAEQKINHLKGFSGGSVKFTVISTAQYFVPKVIQNFTQSYPDVTIIMRVGNKESLIERINNNKDDFYLLGQPPE
DLNVESSQLSVNPLAFLANSDHPLVGKQLSIQDLVNEPFLMRETGSGIRAQIEKVFGEFEFQPNIKMVLGGNEPIRLGLL
QNLGITVASVPTLMEEINQGKISILNVKGFPINRHWYLAYPKGKVLSIAAEKLIELLKIEGEKLSEQAFNQFR

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=214, Percent_Identity=27.5700934579439, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788481, Length=285, Percent_Identity=25.6140350877193, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI145693105, Length=297, Percent_Identity=27.9461279461279, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790399, Length=291, Percent_Identity=25.4295532646048, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788748, Length=297, Percent_Identity=24.9158249158249, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787601, Length=226, Percent_Identity=25.2212389380531, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787879, Length=286, Percent_Identity=24.4755244755245, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788887, Length=276, Percent_Identity=27.536231884058, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790208, Length=250, Percent_Identity=28.4, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=26.4822134387352, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789173, Length=149, Percent_Identity=30.2013422818792, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081904, Length=218, Percent_Identity=25.6880733944954, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788706, Length=134, Percent_Identity=33.5820895522388, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789204, Length=263, Percent_Identity=23.1939163498099, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=205, Percent_Identity=25.8536585365854, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=25.8389261744966, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787128, Length=139, Percent_Identity=26.6187050359712, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35139; Mature: 35008

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEKISILARNATLRQLQVFESIARHNSFSKAAEELHLTQPTVSMQVKKLAEILESPLFE
CCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHH
QIGRKAHLTEAGKALYDSANNILQQLSIAEQKINHLKGFSGGSVKFTVISTAQYFVPKVI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHH
QNFTQSYPDVTIIMRVGNKESLIERINNNKDDFYLLGQPPEDLNVESSQLSVNPLAFLAN
HHHHHCCCCEEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEECCCEEEEEC
SDHPLVGKQLSIQDLVNEPFLMRETGSGIRAQIEKVFGEFEFQPNIKMVLGGNEPIRLGL
CCCCCCCCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHCCEECCCEEEEECCCCCEEEEE
LQNLGITVASVPTLMEEINQGKISILNVKGFPINRHWYLAYPKGKVLSIAAEKLIELLKI
HHHCCCHHHHHHHHHHHHCCCCEEEEEEECCEECCEEEEEECCCCCHHHHHHHHHHHHHH
EGEKLSEQAFNQFR
CCHHHHHHHHHHCC
>Mature Secondary Structure 
PEKISILARNATLRQLQVFESIARHNSFSKAAEELHLTQPTVSMQVKKLAEILESPLFE
CCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHH
QIGRKAHLTEAGKALYDSANNILQQLSIAEQKINHLKGFSGGSVKFTVISTAQYFVPKVI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHH
QNFTQSYPDVTIIMRVGNKESLIERINNNKDDFYLLGQPPEDLNVESSQLSVNPLAFLAN
HHHHHCCCCEEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEECCCEEEEEC
SDHPLVGKQLSIQDLVNEPFLMRETGSGIRAQIEKVFGEFEFQPNIKMVLGGNEPIRLGL
CCCCCCCCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHCCEECCCEEEEECCCCCEEEEE
LQNLGITVASVPTLMEEINQGKISILNVKGFPINRHWYLAYPKGKVLSIAAEKLIELLKI
HHHCCCHHHHHHHHHHHHCCCCEEEEEEECCEECCEEEEEECCCCCHHHHHHHHHHHHHH
EGEKLSEQAFNQFR
CCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]