Click here to switch to the map view.

The map label for this gene is yicO [C]

Identifier: 78484744

GI number: 78484744

Start: 450000

End: 451286

Strand: Reverse

Name: yicO [C]

Synonym: Tcr_0399

Alternate gene names: 78484744

Gene position: 451286-450000 (Counterclockwise)

Preceding gene: 78484745

Following gene: 78484742

Centisome position: 18.59

GC content: 48.87

Gene sequence:

>1287_bases
ATGTTTCATTTAAAACAGCATGGCACCACCGTCAAAACCGAGTTTGTTGCCGGGTTGACGACCTTCTTAACCATGCTGTA
CATCGTGCCGGTCAATGGCTTTATTCTCAGTGATGCCGGTATGCCAATGGCGGCGGTGATTACAGCAACTGCCTTAATTA
CCATTTTTTCAACGTTGCTGAATGGCCTTTGGTCGAACACACCGATTGCGATGAGCGTCGGCATGGGCTTAAACGCTTAC
TTCACTTACGGCTTGGTGCTTGGCATGCAGATTCCCTGGCAAACGGCTTTGGGCGTGGTGTTTCTGTCCGGTGTTTTATT
TGTCATTTTATCGTTCACCCCTTTCCGTGCTTGGATGATGTCATCTATTCCAATCGATTTACGCCGTGCTATCAGTGCCG
GGATTGGGGCGTTTATTGCCTTTATCGGTTTGGAACAAATGGGCGTCATCACTCATAATGATGCCACGTTGGTGGCATTA
GGCGACTTTTCGTCCCCTCAGGTGCTCTTAGGCATCGTTGGCTTTTTCTTAGCGCTCATCGCCTATGCTTATAAAATGAA
AGGCGCCTTTGTGCTCTCCATTGCCATCACCGCCCTCATCGGCTGGGCGTTCGGCCTTGCGAAAATGCCGGAATCTTTTT
TCAGCCTACCTGCGTCCATCGCCCCCATTGCCTTGGAGCTGGATATTGTTTCGGCCTTCACCTTGTCGTTGTTGCCGGTG
ATTCTAATTTTTTTAATCACCGACATGTTCGATACCCTTGGCAGTGTGACCGGCATTGGCATGCGGGCGCAATTGTTTCA
AACGTCGGATAAAAAAAATTACTCACTGGAAAACACCCTGAAAGCGGATGCGTTATCCACCGTGGCCGGCAGCACCGTTG
GTGTCACCTCGGTCACCGCCTTCATTGAATCGGCCACCGGCATTGAACAAGGTGGCCGAACCGGTCTGACAGCCGTTTTT
ACCGGCTTATTGTTTATCAGCACCTTGTTTATGCTGCCCCTCTTTCAGGCCTTACCGCAAAATGCCATTTACCCCATTCT
GGTGATCGTGGGCATTTTAATGTTCAGCGAGTTGGGGAAAGTGGCGTTTAAAGAAAGCGATTTAGGCACCAATGCGGCAG
TTTTTTTGATTGTGTTACTGATGCCGCTCACCTATTCCATCACCACCGGTGTCGCCGCAGGGTTTCTAGTGTACGTAGCG
TTAAAACTGGTGAAAAAAGAATTTCAGGATTTAAATCTGGGCATTATCGTCATTGCTTTGATCAGTGGGCTGGTGTTTAT
TCTGTAA

Upstream 100 bases:

>100_bases
TTATTTGATGCAACAGATATGGTTACAAGGGCTTATTGCACTGTTAGGGCTTTATTTCCTTTTTAAAAAACCATAATCTC
TCGGACGAGAAAGGCACGCG

Downstream 100 bases:

>100_bases
TGCCCGCAAGCGTGTTTACAAGGAACCTTATGATTCGTTCTTGTGAAAGCAGGCTAAAAACCGCCAGGCCTGGGCGTTTT
TAGCTCTCATTACCTTCTTT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFHLKQHGTTVKTEFVAGLTTFLTMLYIVPVNGFILSDAGMPMAAVITATALITIFSTLLNGLWSNTPIAMSVGMGLNAY
FTYGLVLGMQIPWQTALGVVFLSGVLFVILSFTPFRAWMMSSIPIDLRRAISAGIGAFIAFIGLEQMGVITHNDATLVAL
GDFSSPQVLLGIVGFFLALIAYAYKMKGAFVLSIAITALIGWAFGLAKMPESFFSLPASIAPIALELDIVSAFTLSLLPV
ILIFLITDMFDTLGSVTGIGMRAQLFQTSDKKNYSLENTLKADALSTVAGSTVGVTSVTAFIESATGIEQGGRTGLTAVF
TGLLFISTLFMLPLFQALPQNAIYPILVIVGILMFSELGKVAFKESDLGTNAAVFLIVLLMPLTYSITTGVAAGFLVYVA
LKLVKKEFQDLNLGIIVIALISGLVFIL

Sequences:

>Translated_428_residues
MFHLKQHGTTVKTEFVAGLTTFLTMLYIVPVNGFILSDAGMPMAAVITATALITIFSTLLNGLWSNTPIAMSVGMGLNAY
FTYGLVLGMQIPWQTALGVVFLSGVLFVILSFTPFRAWMMSSIPIDLRRAISAGIGAFIAFIGLEQMGVITHNDATLVAL
GDFSSPQVLLGIVGFFLALIAYAYKMKGAFVLSIAITALIGWAFGLAKMPESFFSLPASIAPIALELDIVSAFTLSLLPV
ILIFLITDMFDTLGSVTGIGMRAQLFQTSDKKNYSLENTLKADALSTVAGSTVGVTSVTAFIESATGIEQGGRTGLTAVF
TGLLFISTLFMLPLFQALPQNAIYPILVIVGILMFSELGKVAFKESDLGTNAAVFLIVLLMPLTYSITTGVAAGFLVYVA
LKLVKKEFQDLNLGIIVIALISGLVFIL
>Mature_428_residues
MFHLKQHGTTVKTEFVAGLTTFLTMLYIVPVNGFILSDAGMPMAAVITATALITIFSTLLNGLWSNTPIAMSVGMGLNAY
FTYGLVLGMQIPWQTALGVVFLSGVLFVILSFTPFRAWMMSSIPIDLRRAISAGIGAFIAFIGLEQMGVITHNDATLVAL
GDFSSPQVLLGIVGFFLALIAYAYKMKGAFVLSIAITALIGWAFGLAKMPESFFSLPASIAPIALELDIVSAFTLSLLPV
ILIFLITDMFDTLGSVTGIGMRAQLFQTSDKKNYSLENTLKADALSTVAGSTVGVTSVTAFIESATGIEQGGRTGLTAVF
TGLLFISTLFMLPLFQALPQNAIYPILVIVGILMFSELGKVAFKESDLGTNAAVFLIVLLMPLTYSITTGVAAGFLVYVA
LKLVKKEFQDLNLGIIVIALISGLVFIL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=428, Percent_Identity=40.6542056074766, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1790150, Length=423, Percent_Identity=40.1891252955083, Blast_Score=297, Evalue=8e-82,
Organism=Escherichia coli, GI1790499, Length=428, Percent_Identity=35.5140186915888, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI48994909, Length=428, Percent_Identity=34.8130841121495, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45588; Mature: 45588

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHLKQHGTTVKTEFVAGLTTFLTMLYIVPVNGFILSDAGMPMAAVITATALITIFSTLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
NGLWSNTPIAMSVGMGLNAYFTYGLVLGMQIPWQTALGVVFLSGVLFVILSFTPFRAWMM
HHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SSIPIDLRRAISAGIGAFIAFIGLEQMGVITHNDATLVALGDFSSPQVLLGIVGFFLALI
HCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHH
AYAYKMKGAFVLSIAITALIGWAFGLAKMPESFFSLPASIAPIALELDIVSAFTLSLLPV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHH
ILIFLITDMFDTLGSVTGIGMRAQLFQTSDKKNYSLENTLKADALSTVAGSTVGVTSVTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
FIESATGIEQGGRTGLTAVFTGLLFISTLFMLPLFQALPQNAIYPILVIVGILMFSELGK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VAFKESDLGTNAAVFLIVLLMPLTYSITTGVAAGFLVYVALKLVKKEFQDLNLGIIVIAL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ISGLVFIL
HHHHHHHC
>Mature Secondary Structure
MFHLKQHGTTVKTEFVAGLTTFLTMLYIVPVNGFILSDAGMPMAAVITATALITIFSTLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
NGLWSNTPIAMSVGMGLNAYFTYGLVLGMQIPWQTALGVVFLSGVLFVILSFTPFRAWMM
HHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SSIPIDLRRAISAGIGAFIAFIGLEQMGVITHNDATLVALGDFSSPQVLLGIVGFFLALI
HCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHH
AYAYKMKGAFVLSIAITALIGWAFGLAKMPESFFSLPASIAPIALELDIVSAFTLSLLPV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHH
ILIFLITDMFDTLGSVTGIGMRAQLFQTSDKKNYSLENTLKADALSTVAGSTVGVTSVTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
FIESATGIEQGGRTGLTAVFTGLLFISTLFMLPLFQALPQNAIYPILVIVGILMFSELGK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VAFKESDLGTNAAVFLIVLLMPLTYSITTGVAAGFLVYVALKLVKKEFQDLNLGIIVIAL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ISGLVFIL
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]