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The map label for this gene is rsmB [H]

Identifier: 78484536

GI number: 78484536

Start: 225057

End: 226367

Strand: Reverse

Name: rsmB [H]

Synonym: Tcr_0191

Alternate gene names: 78484536

Gene position: 226367-225057 (Counterclockwise)

Preceding gene: 78484537

Following gene: 78484535

Centisome position: 9.32

GC content: 47.22

Gene sequence:

>1311_bases
ATGGCCGTTAACAGTCGCTATATCGCTTTGAAAATTTGTTTAACCGTCATTGAGCATGGACGCTCTTTAAGCCAATCTTT
AGCAGAAGGCCTGGCACAATTCAGCGATCGACGCGAGCGCGCCTTTACCCAAAATCTGGTACTGGGCACGTTACGTTGGC
AAGAACGTTTGGAAGCCATTCGAAGCCATTTATTAAAAAAACCGTTAAAAGCCAAAGACGAAGACGTTAATCAACTCATA
TTGTTGGGACTCTATCAAATTCTGTATATGGATACCCCGGAGCATGCGGCTGTTTCTGAAACCGTCAATCTCACCAAATC
ATTGAAAAAGCCTTGGGCAAGAGGTCTCATCAACGGAGTGTTAAGAACTTTTCTTCGGGATAAAGACAGCATTTGCGAGG
AAGTCGATAAAAAACCAGCTTATCGTTACTCGCACCCGCAATGGTTTACCAAAACCATACGAAACGCTTATCCCGATCAC
TGGGAGCAGATTTTATCGGCTAATAATGAGCCAGCTCCGTTAACCTTACGCGTGAACCCACTTTACCAAACCCGGGAAGC
GTTTTTAGCCCTGCTGTCAGACCAAGCTGTGGAAGCGGATATCCACCCGAAAGCTCCGCAGGGCATCGTGTTAAAAAACA
GTTTGGACATTACACAATTGCCCACTTATGACGAAGGGGGATTCAGTGTGCAGGATGCGGCGGCGCAACAAGCGGCTTAC
TTATTGGCTCCCCAGCCGAATGAATTTATTCTCGACGCCTGCGCCGCCCCCGGAGGCAAAACCACACATCTTTTGGAACT
GAGTGATAACCAGGCCAAGGTATTTGCCTTAGAAAAAGAGCCGGAACGTATTGAACGCTTGTCTGAAAATCTATACCGCC
TGGCCCTCACCGCTGAAATTGAAGTTGGTGATGCCTCACAACCCGATCAATGGTGGCCGGAAATTCAATTTGATAAAATC
TTATTGGATGCGCCTTGTTCCGCCACGGGCATTATTCGACGCCATCCCGATATTAAATGGCATCGAACGCCTGAAGACAT
TACCGTCCTGACGCAATTACAGGCGGCTATCCTGCAAGCTATTTGGCCTAGATTAAAGCCGGGCGGAAAACTACTCTATG
CCACCTGCTCGGTCTTACCGCAGGAAAATCGAGATCAAATCTCACAATTTCTTCAACAGACACCTGATGCGAAAGAAATA
CCCATTGGAGCGGACTGGGGGATTACAATTGATGCACCCGGTCGACAAATTTTGCCAGGCCAGGATGGCATGGACGGCTT
TTATTATTGCTTAATTGAAAAGGGTTGTTAA

Upstream 100 bases:

>100_bases
ATTACTAATTAAGCAGGTACAACCGTCGGGCAAAAAAGCCATGCCTGCTTATGACTTTGCGCAAGCTCGCCAGCTGACTG
GCCAAACATTAGGATAATAC

Downstream 100 bases:

>100_bases
ACCATGAAAATGCTGGGTGTTGATACGATTCTTTTTTCATTTTTAAAACGCCTTAGCTTACTGATGACACTAGGGTTCAG
TTCGCTCATTCATGCGGCTG

Product: sun protein

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MAVNSRYIALKICLTVIEHGRSLSQSLAEGLAQFSDRRERAFTQNLVLGTLRWQERLEAIRSHLLKKPLKAKDEDVNQLI
LLGLYQILYMDTPEHAAVSETVNLTKSLKKPWARGLINGVLRTFLRDKDSICEEVDKKPAYRYSHPQWFTKTIRNAYPDH
WEQILSANNEPAPLTLRVNPLYQTREAFLALLSDQAVEADIHPKAPQGIVLKNSLDITQLPTYDEGGFSVQDAAAQQAAY
LLAPQPNEFILDACAAPGGKTTHLLELSDNQAKVFALEKEPERIERLSENLYRLALTAEIEVGDASQPDQWWPEIQFDKI
LLDAPCSATGIIRRHPDIKWHRTPEDITVLTQLQAAILQAIWPRLKPGGKLLYATCSVLPQENRDQISQFLQQTPDAKEI
PIGADWGITIDAPGRQILPGQDGMDGFYYCLIEKGC

Sequences:

>Translated_436_residues
MAVNSRYIALKICLTVIEHGRSLSQSLAEGLAQFSDRRERAFTQNLVLGTLRWQERLEAIRSHLLKKPLKAKDEDVNQLI
LLGLYQILYMDTPEHAAVSETVNLTKSLKKPWARGLINGVLRTFLRDKDSICEEVDKKPAYRYSHPQWFTKTIRNAYPDH
WEQILSANNEPAPLTLRVNPLYQTREAFLALLSDQAVEADIHPKAPQGIVLKNSLDITQLPTYDEGGFSVQDAAAQQAAY
LLAPQPNEFILDACAAPGGKTTHLLELSDNQAKVFALEKEPERIERLSENLYRLALTAEIEVGDASQPDQWWPEIQFDKI
LLDAPCSATGIIRRHPDIKWHRTPEDITVLTQLQAAILQAIWPRLKPGGKLLYATCSVLPQENRDQISQFLQQTPDAKEI
PIGADWGITIDAPGRQILPGQDGMDGFYYCLIEKGC
>Mature_435_residues
AVNSRYIALKICLTVIEHGRSLSQSLAEGLAQFSDRRERAFTQNLVLGTLRWQERLEAIRSHLLKKPLKAKDEDVNQLIL
LGLYQILYMDTPEHAAVSETVNLTKSLKKPWARGLINGVLRTFLRDKDSICEEVDKKPAYRYSHPQWFTKTIRNAYPDHW
EQILSANNEPAPLTLRVNPLYQTREAFLALLSDQAVEADIHPKAPQGIVLKNSLDITQLPTYDEGGFSVQDAAAQQAAYL
LAPQPNEFILDACAAPGGKTTHLLELSDNQAKVFALEKEPERIERLSENLYRLALTAEIEVGDASQPDQWWPEIQFDKIL
LDAPCSATGIIRRHPDIKWHRTPEDITVLTQLQAAILQAIWPRLKPGGKLLYATCSVLPQENRDQISQFLQQTPDAKEIP
IGADWGITIDAPGRQILPGQDGMDGFYYCLIEKGC

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=346, Percent_Identity=30.3468208092486, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI76150623, Length=346, Percent_Identity=30.3468208092486, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI8922322, Length=249, Percent_Identity=30.9236947791165, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI270288816, Length=247, Percent_Identity=31.1740890688259, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI270288818, Length=249, Percent_Identity=30.9236947791165, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI23199998, Length=249, Percent_Identity=30.5220883534137, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI32698918, Length=200, Percent_Identity=34, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI301336155, Length=279, Percent_Identity=28.673835125448, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI39995082, Length=306, Percent_Identity=27.1241830065359, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI40316918, Length=182, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI2367212, Length=432, Percent_Identity=45.6018518518519, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI87081985, Length=269, Percent_Identity=28.996282527881, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17536757, Length=333, Percent_Identity=28.2282282282282, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25143471, Length=223, Percent_Identity=34.0807174887892, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71998419, Length=173, Percent_Identity=32.3699421965318, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115534021, Length=173, Percent_Identity=32.9479768786127, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=358, Percent_Identity=28.2122905027933, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319447, Length=284, Percent_Identity=26.4084507042254, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324306, Length=244, Percent_Identity=27.0491803278689, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI22024126, Length=312, Percent_Identity=30.1282051282051, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21355201, Length=317, Percent_Identity=27.1293375394322, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668781, Length=227, Percent_Identity=28.1938325991189, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356513, Length=202, Percent_Identity=30.1980198019802, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356579, Length=228, Percent_Identity=27.6315789473684, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920494, Length=191, Percent_Identity=33.5078534031414, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 49119; Mature: 48987

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNSRYIALKICLTVIEHGRSLSQSLAEGLAQFSDRRERAFTQNLVLGTLRWQERLEAI
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHLLKKPLKAKDEDVNQLILLGLYQILYMDTPEHAAVSETVNLTKSLKKPWARGLINGV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTFLRDKDSICEEVDKKPAYRYSHPQWFTKTIRNAYPDHWEQILSANNEPAPLTLRVNP
HHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECC
LYQTREAFLALLSDQAVEADIHPKAPQGIVLKNSLDITQLPTYDEGGFSVQDAAAQQAAY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHEE
LLAPQPNEFILDACAAPGGKTTHLLELSDNQAKVFALEKEPERIERLSENLYRLALTAEI
EECCCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHEEEEEEEEE
EVGDASQPDQWWPEIQFDKILLDAPCSATGIIRRHPDIKWHRTPEDITVLTQLQAAILQA
EECCCCCCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
IWPRLKPGGKLLYATCSVLPQENRDQISQFLQQTPDAKEIPIGADWGITIDAPGRQILPG
HHHCCCCCCEEEEEEEHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEECCC
QDGMDGFYYCLIEKGC
CCCCCCEEEEEEECCC
>Mature Secondary Structure 
AVNSRYIALKICLTVIEHGRSLSQSLAEGLAQFSDRRERAFTQNLVLGTLRWQERLEAI
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHLLKKPLKAKDEDVNQLILLGLYQILYMDTPEHAAVSETVNLTKSLKKPWARGLINGV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTFLRDKDSICEEVDKKPAYRYSHPQWFTKTIRNAYPDHWEQILSANNEPAPLTLRVNP
HHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECC
LYQTREAFLALLSDQAVEADIHPKAPQGIVLKNSLDITQLPTYDEGGFSVQDAAAQQAAY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHEE
LLAPQPNEFILDACAAPGGKTTHLLELSDNQAKVFALEKEPERIERLSENLYRLALTAEI
EECCCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHEEEEEEEEE
EVGDASQPDQWWPEIQFDKILLDAPCSATGIIRRHPDIKWHRTPEDITVLTQLQAAILQA
EECCCCCCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
IWPRLKPGGKLLYATCSVLPQENRDQISQFLQQTPDAKEIPIGADWGITIDAPGRQILPG
HHHCCCCCCEEEEEEEHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEECCC
QDGMDGFYYCLIEKGC
CCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]