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The map label for this gene is 78484427

Identifier: 78484427

GI number: 78484427

Start: 102827

End: 103723

Strand: Reverse

Name: 78484427

Synonym: Tcr_0081

Alternate gene names: NA

Gene position: 103723-102827 (Counterclockwise)

Preceding gene: 78484428

Following gene: 78484426

Centisome position: 4.27

GC content: 46.15

Gene sequence:

>897_bases
ATGTCAAAAAACACCTCTCACCTGACCCAACTGTTATTCAAAGAACTGGCTAAACAACCCAAATTGCTGCAAATCAGCTT
TTTCTGGCTTCCGGTAATATTTGGTTTTGTCCTGCTGGCCGGCGGCTTAAAGTATGTTTATGAAACCGAAGTCGCGCGCC
CTGCGATGGCGTATATGGGCGTTCCTAAAAGTAATCATGATTGGTCAAACTTAACCCATACCTTGCGTAATAAAGGGTTT
ATGTTGGCCTACTCCGAAAGACTCGCCAACCCGATCTGGGTAACCTACAAAGTAACACCGACCAAAGTTAAGTATGGCAA
GCGCCCTCACTTTCAGGCCGACTGGCGCTCACTGGCGCATATTCGCCATGAAGACTATACCAGCAGTGGTTATGATCGCG
GGCATATGGCGCCTAACTATGTCATCGCCAGCCGTTATGGCTATGAAGCTCAAAAAGAAACGTTTCTGATGACGAATATC
ACCCCACAAAAACCCAGTTTTAATCAGAAAATCTGGCAACGACTGGAAGAGGTCAGTGCCGATGTTTTTTCAAAACAAGT
CGGCACTTTTTGGGTCGTCACCGGTCCCATTTTTGACGCGAAGCCTAACACCCTGAAAAAAGCACCGGTGGCTATTCCAA
AAGCCTTTTATAAAATCTTTATTCGCCCAGAAATAGACGGCAAGCCCACCATTGCGTTGGCGTTTATTCTGCCGCAGACT
GCCAAACCAAAAGACAGTTTGCTAAACTACGTCACAACCATTGATCAGATTGAGCAACAAACGGGAATCGATTTTTTCTG
GCAGTTAGAAGACACCCTAGAAACGGCCCTTGAAGCAAGCAAAAACCCCCAGGCCTGGTCTTTAGAAAAAGTGGCTAATT
TACCCAGCCGCTATTAA

Upstream 100 bases:

>100_bases
CAATACTGTCGGCGTCCCACATATCGCGATATGGGGCGTTACATTCATATTCTCGCACGCAAAGCGATTTTATAAACCAA
CGGAACAATCAAAACTCAGT

Downstream 100 bases:

>100_bases
AGGAGAAACATGAAACGTCGCCAATTTCTTGCCCTATTGTCCAGCACTGGATTGGTGTCCGCCTGCACCGTGACCGAAGT
TCGGCGTGGTATCAACTCGG

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSKNTSHLTQLLFKELAKQPKLLQISFFWLPVIFGFVLLAGGLKYVYETEVARPAMAYMGVPKSNHDWSNLTHTLRNKGF
MLAYSERLANPIWVTYKVTPTKVKYGKRPHFQADWRSLAHIRHEDYTSSGYDRGHMAPNYVIASRYGYEAQKETFLMTNI
TPQKPSFNQKIWQRLEEVSADVFSKQVGTFWVVTGPIFDAKPNTLKKAPVAIPKAFYKIFIRPEIDGKPTIALAFILPQT
AKPKDSLLNYVTTIDQIEQQTGIDFFWQLEDTLETALEASKNPQAWSLEKVANLPSRY

Sequences:

>Translated_298_residues
MSKNTSHLTQLLFKELAKQPKLLQISFFWLPVIFGFVLLAGGLKYVYETEVARPAMAYMGVPKSNHDWSNLTHTLRNKGF
MLAYSERLANPIWVTYKVTPTKVKYGKRPHFQADWRSLAHIRHEDYTSSGYDRGHMAPNYVIASRYGYEAQKETFLMTNI
TPQKPSFNQKIWQRLEEVSADVFSKQVGTFWVVTGPIFDAKPNTLKKAPVAIPKAFYKIFIRPEIDGKPTIALAFILPQT
AKPKDSLLNYVTTIDQIEQQTGIDFFWQLEDTLETALEASKNPQAWSLEKVANLPSRY
>Mature_297_residues
SKNTSHLTQLLFKELAKQPKLLQISFFWLPVIFGFVLLAGGLKYVYETEVARPAMAYMGVPKSNHDWSNLTHTLRNKGFM
LAYSERLANPIWVTYKVTPTKVKYGKRPHFQADWRSLAHIRHEDYTSSGYDRGHMAPNYVIASRYGYEAQKETFLMTNIT
PQKPSFNQKIWQRLEEVSADVFSKQVGTFWVVTGPIFDAKPNTLKKAPVAIPKAFYKIFIRPEIDGKPTIALAFILPQTA
KPKDSLLNYVTTIDQIEQQTGIDFFWQLEDTLETALEASKNPQAWSLEKVANLPSRY

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI53759134, Length=205, Percent_Identity=28.2926829268293, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI224451073, Length=215, Percent_Identity=26.5116279069767, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI224451075, Length=165, Percent_Identity=29.6969696969697, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17505967, Length=229, Percent_Identity=24.4541484716157, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322253, Length=237, Percent_Identity=27.0042194092827, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24581065, Length=229, Percent_Identity=29.2576419213974, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI20129899, Length=232, Percent_Identity=25.8620689655172, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: NA

Molecular weight: Translated: 34217; Mature: 34086

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNTSHLTQLLFKELAKQPKLLQISFFWLPVIFGFVLLAGGLKYVYETEVARPAMAYMG
CCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHC
VPKSNHDWSNLTHTLRNKGFMLAYSERLANPIWVTYKVTPTKVKYGKRPHFQADWRSLAH
CCCCCCCHHHHHHHHHCCCEEEEEHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
IRHEDYTSSGYDRGHMAPNYVIASRYGYEAQKETFLMTNITPQKPSFNQKIWQRLEEVSA
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
DVFSKQVGTFWVVTGPIFDAKPNTLKKAPVAIPKAFYKIFIRPEIDGKPTIALAFILPQT
HHHHHCCCEEEEEECCEECCCCCCCCCCCHHHHHHHHEEEEEECCCCCCCEEEEEEECCC
AKPKDSLLNYVTTIDQIEQQTGIDFFWQLEDTLETALEASKNPQAWSLEKVANLPSRY
CCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCCC
>Mature Secondary Structure 
SKNTSHLTQLLFKELAKQPKLLQISFFWLPVIFGFVLLAGGLKYVYETEVARPAMAYMG
CCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHC
VPKSNHDWSNLTHTLRNKGFMLAYSERLANPIWVTYKVTPTKVKYGKRPHFQADWRSLAH
CCCCCCCHHHHHHHHHCCCEEEEEHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
IRHEDYTSSGYDRGHMAPNYVIASRYGYEAQKETFLMTNITPQKPSFNQKIWQRLEEVSA
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
DVFSKQVGTFWVVTGPIFDAKPNTLKKAPVAIPKAFYKIFIRPEIDGKPTIALAFILPQT
HHHHHCCCEEEEEECCEECCCCCCCCCCCHHHHHHHHEEEEEECCCCCCCEEEEEEECCC
AKPKDSLLNYVTTIDQIEQQTGIDFFWQLEDTLETALEASKNPQAWSLEKVANLPSRY
CCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]