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The map label for this gene is rsgA2 [H]

Identifier: 78484382

GI number: 78484382

Start: 44664

End: 45698

Strand: Reverse

Name: rsgA2 [H]

Synonym: Tcr_0036

Alternate gene names: 78484382

Gene position: 45698-44664 (Counterclockwise)

Preceding gene: 78484383

Following gene: 78484376

Centisome position: 1.88

GC content: 49.95

Gene sequence:

>1035_bases
ATGACACCACATTATTCTCTTCATCAATTAGGGTGGAAACCCTTTTTTCAACACCAACTGTCACTTTATGAGTTGGAAAC
CTTGATTCCGGCGCGTGTCTTTGGCATCGAACGTTCGATTATCCAGTTATTGACCACCGAAGGTCCGTTGTCCATGGCGA
TGACACAATCCATTCCGAATCTGGCGGTGGGCGACTGGATTTTAATCGATGCTCAGCATCGGTTTGTTCGCTTGTTGGAC
AGGGCGTCGTTGTTTTCGCGAAAGGCAGCGGGTACAAGGGTTGACCGCCAACTGATTTCCGCCAATGTGGAGTCGGTTTT
GATTGTCAGTTCTCTGAACAACGACTTTAATTTGAACCGGATTGAGCGTTATTTAGCGTTGGCGCATGAAGCTGGTGTAG
AACCGATTGTTTTGCTTACCAAAGCCGATTTATGCGATGATCCCGAATCGTTTGTCGAAGCGGTTCAAGAGTTGGCTCAG
ATGCTGCCGGTGTTTGCGGTCAATGCTCATGATTGGGCGACTTTGCAAACGCTCGAAATGTGGCTGTCGCCAGGCCATAC
TCTGGCTTTTTTTGGGTCGTCCGGCGTGGGAAAATCGACGTTGGTGAACACGCTATTGGGCGGTGAAGTGCAGGAAACCA
ATCAAGTTCGTGAAGATGACAGCCGAGGGCGTCACACCACGACAGCCCGTTCGCTGCATTTGACGGCTTCTGGCGTGTTG
TTGTTGGACACGCCGGGCATGCGAGAGTTGCAATTGGCGGATTGCGAACAGGGCGTAGAGGAAACCTTTGCAGACATTGC
ATCTTTGGCGACGCGGTGTAAGTTTTCTGATTGCCAGCATGAATCTGAACCGGGGTGTGCGGTTCAGGCTGCGATTCAAT
CCGGGCAGCTGGCAGAGCGCCGCTTGGTGAATTATCATAAGTTGATGAAGGAGCAAGCGTTTAATGCCGTTACTTTGGCG
GAGAAACGTGCAAAAGACAAGCGATTCAGCAAGTTGGTTAAATCCGCCAAAAATATCAAGCAACAACCTACATAA

Upstream 100 bases:

>100_bases
TTTTTCGTAGATTTATTCTTCGCTACCCGGTCTGAGCACCGGGGCGTTTTCAGCCCCAAAGTTTGATTTCTTACAACGCT
TAAGCGTTATGGGGCCTATG

Downstream 100 bases:

>100_bases
AGCTGTTTTACGATACCCGCCAGACCTGGTCAATTTAGAACATTAATGAATAGGAGAGCGGGTTGTTTATAAATCCAGTT
TTTTCATGCGGTAACTGAAT

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTPHYSLHQLGWKPFFQHQLSLYELETLIPARVFGIERSIIQLLTTEGPLSMAMTQSIPNLAVGDWILIDAQHRFVRLLD
RASLFSRKAAGTRVDRQLISANVESVLIVSSLNNDFNLNRIERYLALAHEAGVEPIVLLTKADLCDDPESFVEAVQELAQ
MLPVFAVNAHDWATLQTLEMWLSPGHTLAFFGSSGVGKSTLVNTLLGGEVQETNQVREDDSRGRHTTTARSLHLTASGVL
LLDTPGMRELQLADCEQGVEETFADIASLATRCKFSDCQHESEPGCAVQAAIQSGQLAERRLVNYHKLMKEQAFNAVTLA
EKRAKDKRFSKLVKSAKNIKQQPT

Sequences:

>Translated_344_residues
MTPHYSLHQLGWKPFFQHQLSLYELETLIPARVFGIERSIIQLLTTEGPLSMAMTQSIPNLAVGDWILIDAQHRFVRLLD
RASLFSRKAAGTRVDRQLISANVESVLIVSSLNNDFNLNRIERYLALAHEAGVEPIVLLTKADLCDDPESFVEAVQELAQ
MLPVFAVNAHDWATLQTLEMWLSPGHTLAFFGSSGVGKSTLVNTLLGGEVQETNQVREDDSRGRHTTTARSLHLTASGVL
LLDTPGMRELQLADCEQGVEETFADIASLATRCKFSDCQHESEPGCAVQAAIQSGQLAERRLVNYHKLMKEQAFNAVTLA
EKRAKDKRFSKLVKSAKNIKQQPT
>Mature_343_residues
TPHYSLHQLGWKPFFQHQLSLYELETLIPARVFGIERSIIQLLTTEGPLSMAMTQSIPNLAVGDWILIDAQHRFVRLLDR
ASLFSRKAAGTRVDRQLISANVESVLIVSSLNNDFNLNRIERYLALAHEAGVEPIVLLTKADLCDDPESFVEAVQELAQM
LPVFAVNAHDWATLQTLEMWLSPGHTLAFFGSSGVGKSTLVNTLLGGEVQETNQVREDDSRGRHTTTARSLHLTASGVLL
LDTPGMRELQLADCEQGVEETFADIASLATRCKFSDCQHESEPGCAVQAAIQSGQLAERRLVNYHKLMKEQAFNAVTLAE
KRAKDKRFSKLVKSAKNIKQQPT

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover [H]

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain [H]

Homologues:

Organism=Escherichia coli, GI87082381, Length=220, Percent_Identity=36.3636363636364, Blast_Score=144, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010914
- InterPro:   IPR004881 [H]

Pfam domain/function: PF03193 DUF258 [H]

EC number: NA

Molecular weight: Translated: 38233; Mature: 38102

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHYSLHQLGWKPFFQHQLSLYELETLIPARVFGIERSIIQLLTTEGPLSMAMTQSIPN
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
LAVGDWILIDAQHRFVRLLDRASLFSRKAAGTRVDRQLISANVESVLIVSSLNNDFNLNR
CCCCCEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCHHH
IERYLALAHEAGVEPIVLLTKADLCDDPESFVEAVQELAQMLPVFAVNAHDWATLQTLEM
HHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHH
WLSPGHTLAFFGSSGVGKSTLVNTLLGGEVQETNQVREDDSRGRHTTTARSLHLTASGVL
HHCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHEEEEEECCEE
LLDTPGMRELQLADCEQGVEETFADIASLATRCKFSDCQHESEPGCAVQAAIQSGQLAER
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHCCHHHHH
RLVNYHKLMKEQAFNAVTLAEKRAKDKRFSKLVKSAKNIKQQPT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPHYSLHQLGWKPFFQHQLSLYELETLIPARVFGIERSIIQLLTTEGPLSMAMTQSIPN
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
LAVGDWILIDAQHRFVRLLDRASLFSRKAAGTRVDRQLISANVESVLIVSSLNNDFNLNR
CCCCCEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCHHH
IERYLALAHEAGVEPIVLLTKADLCDDPESFVEAVQELAQMLPVFAVNAHDWATLQTLEM
HHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHH
WLSPGHTLAFFGSSGVGKSTLVNTLLGGEVQETNQVREDDSRGRHTTTARSLHLTASGVL
HHCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHEEEEEECCEE
LLDTPGMRELQLADCEQGVEETFADIASLATRCKFSDCQHESEPGCAVQAAIQSGQLAER
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHCCHHHHH
RLVNYHKLMKEQAFNAVTLAEKRAKDKRFSKLVKSAKNIKQQPT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]