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The map label for this gene is glpR [H]

Identifier: 78358770

GI number: 78358770

Start: 3688805

End: 3689569

Strand: Reverse

Name: glpR [H]

Synonym: Dde_3731

Alternate gene names: 78358770

Gene position: 3689569-3688805 (Counterclockwise)

Preceding gene: 78358773

Following gene: 78358769

Centisome position: 98.91

GC content: 58.04

Gene sequence:

>765_bases
ATGAGCAAAAGCGCGGTTCGACACAAATCGTTACAGGAGTTCCTTGCCGAGAGGGGATATGCCACCATCGAAGAACTGGC
CGTCCGTTTCGGAGTGACTCCTCAGACCATCCGTAAAGATATAAACACGCTGGCCGCCGAAGGCCGGCTGCAGCGCTTTC
ACGGTGGGGCGGGGGTGCCTCTGGGCTCCAGCAACATTGTGTACGATCAGCGTAAATCCATGTTTATGGACGAAAAGCGG
CGCATAGGCGAGCTGGTGGCCCAGCATATTCCGGAAGGTGCTTCGCTGTGCATAAACATAGGCACCACCACGGAAGCAGT
GGCCCGCGCCCTGCTGGCTCATAAAGGCCTGCGGGTGGTGACCAACAGCCTTAACGTGGCTTCCATTCTTGCCCAGAATT
CATCACATGACGTTGTGGTGGCGGGGGGTACTGTCCGCCACAGAGACAACGGCATAGTGGGGCCCAGCGCAGAACGCTTC
ATACGCGAATTCCGGGTGGATTACGGCATCATCGGCATTTCAGGCATAGATGAAGACGGTAATCTGCTGGATTACGACTA
CCGCGAGGTGGCTGTGGCCCGTACCATCATCGAGTGTTCGCGCCATGTGTACATGGTGACTGATAACTCCAAGTTCGGCC
GGCCTGCCATGGTGCGCATGGCGCGCCTGAGCGACCTGACGGCGCTGTTCTCCAACGGGCCGCTGCCTTCGCCGCAGTGG
GAAACGCTGGTAAAGGAATCAGGCGCGGAACTGTTTCTTGCCTGA

Upstream 100 bases:

>100_bases
TATCCGAGCATGATACGCCGCGCCTGTATGTCTGTCCAGCACGGGCGGCCGCAGTGCCGGAACCCTTGTTTTCTGCGTCC
AGCAACGCTAAAGTGCGCCC

Downstream 100 bases:

>100_bases
TGTCTGCCGCATACGCCGGCGGGCATTGCCTCTTTGCCGGGCGCTGTCTTTTTCGGCCGGGAAATCAAAGAATTCAAAAA
GCGTCTCATACGCGCCTTTC

Product: regulatory protein, DeoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSKSAVRHKSLQEFLAERGYATIEELAVRFGVTPQTIRKDINTLAAEGRLQRFHGGAGVPLGSSNIVYDQRKSMFMDEKR
RIGELVAQHIPEGASLCINIGTTTEAVARALLAHKGLRVVTNSLNVASILAQNSSHDVVVAGGTVRHRDNGIVGPSAERF
IREFRVDYGIIGISGIDEDGNLLDYDYREVAVARTIIECSRHVYMVTDNSKFGRPAMVRMARLSDLTALFSNGPLPSPQW
ETLVKESGAELFLA

Sequences:

>Translated_254_residues
MSKSAVRHKSLQEFLAERGYATIEELAVRFGVTPQTIRKDINTLAAEGRLQRFHGGAGVPLGSSNIVYDQRKSMFMDEKR
RIGELVAQHIPEGASLCINIGTTTEAVARALLAHKGLRVVTNSLNVASILAQNSSHDVVVAGGTVRHRDNGIVGPSAERF
IREFRVDYGIIGISGIDEDGNLLDYDYREVAVARTIIECSRHVYMVTDNSKFGRPAMVRMARLSDLTALFSNGPLPSPQW
ETLVKESGAELFLA
>Mature_253_residues
SKSAVRHKSLQEFLAERGYATIEELAVRFGVTPQTIRKDINTLAAEGRLQRFHGGAGVPLGSSNIVYDQRKSMFMDEKRR
IGELVAQHIPEGASLCINIGTTTEAVARALLAHKGLRVVTNSLNVASILAQNSSHDVVVAGGTVRHRDNGIVGPSAERFI
REFRVDYGIIGISGIDEDGNLLDYDYREVAVARTIIECSRHVYMVTDNSKFGRPAMVRMARLSDLTALFSNGPLPSPQWE
TLVKESGAELFLA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=234, Percent_Identity=49.5726495726496, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI87082344, Length=247, Percent_Identity=41.2955465587045, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1788069, Length=247, Percent_Identity=27.9352226720648, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=30.5220883534137, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=26.5060240963855, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=24, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787540, Length=208, Percent_Identity=27.4038461538462, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790635, Length=239, Percent_Identity=25.1046025104602, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787063, Length=207, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790753, Length=253, Percent_Identity=23.7154150197628, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27838; Mature: 27707

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSAVRHKSLQEFLAERGYATIEELAVRFGVTPQTIRKDINTLAAEGRLQRFHGGAGVP
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGSSNIVYDQRKSMFMDEKRRIGELVAQHIPEGASLCINIGTTTEAVARALLAHKGLRVV
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCHHHH
TNSLNVASILAQNSSHDVVVAGGTVRHRDNGIVGPSAERFIREFRVDYGIIGISGIDEDG
HCCCHHHHHHHCCCCCCEEEECCEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCC
NLLDYDYREVAVARTIIECSRHVYMVTDNSKFGRPAMVRMARLSDLTALFSNGPLPSPQW
CEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
ETLVKESGAELFLA
HHHHHHCCCCEECC
>Mature Secondary Structure 
SKSAVRHKSLQEFLAERGYATIEELAVRFGVTPQTIRKDINTLAAEGRLQRFHGGAGVP
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGSSNIVYDQRKSMFMDEKRRIGELVAQHIPEGASLCINIGTTTEAVARALLAHKGLRVV
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCHHHH
TNSLNVASILAQNSSHDVVVAGGTVRHRDNGIVGPSAERFIREFRVDYGIIGISGIDEDG
HCCCHHHHHHHCCCCCCEEEECCEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCC
NLLDYDYREVAVARTIIECSRHVYMVTDNSKFGRPAMVRMARLSDLTALFSNGPLPSPQW
CEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
ETLVKESGAELFLA
HHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]