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The map label for this gene is ntrX [H]

Identifier: 78358756

GI number: 78358756

Start: 3676621

End: 3677826

Strand: Reverse

Name: ntrX [H]

Synonym: Dde_3717

Alternate gene names: 78358756

Gene position: 3677826-3676621 (Counterclockwise)

Preceding gene: 78358757

Following gene: 78358755

Centisome position: 98.6

GC content: 60.36

Gene sequence:

>1206_bases
ATGCCGGATCTGACAGCGGCAGCGGAGTCTGCACCTCTTTCTGTCATGCTTGTAGATGATGAGCCGGGCATTCTGGCAAC
AATGGGGCCTCTTGTTGCCGATATGGGGTATCAGGTTGTTACGGCTCAGTCCGGCGAAGCCGCGCTGCAGCTGGCACATG
ACAGCCGGCCGCCCCATGTGTTGCTGACCGATGTGCGCATGCCCGTTATGGACGGCATGGCCCTGCTGCGCGCCTTTAAA
ACAGCCTGGCCCGATACGGAAGTGCTGATGCTGACCGGACATGGCGACATGCAGCTGGCAGTGGAAAGTCTGCGGCAGGG
GGCCGGTGATTTTCTGACCAAGCCCGTTAATGCCGATGTGCTGGAATTTGCGCTGGCCCGCGCCGCAGAACGGATTGCTC
TGCGGGGGCAGGTGCGGCGCTATACCAGCCAGCTGGAATCACTGGTGGAACAGCGCACCCGCGAGTTGCTGGAAGCCGAA
CGCCTTGCCGCCATGGGGGAAACTGCCGGTACCATGGCACACGCCATCAAGAATCTGGCCGGAGGGCTGGAAGGGGCTAT
GTTTGTACTGGAAAAAGGGCTGGAACTTGATAACCGCGAGTATCTTGAGCAGGGCTGGCAGATGCTGCGTAAAGATGTGG
GCAGACTGCGTGACATGGCAATGAACCTGTTGCATCTTTCCAGACCGGCACAACCTGATATGCAGCCCGGCGATCCTCTG
GGCGTGGCGCGCGATGTTGTCCGGCTGCTGCAAAGCAGAGCGGCGGATGCCGGAGCGCTGTTGCGCCTTGAACCGTCGCA
CCAATCTGAAAATGCCAAAAAATCCGGAAGTGCGCTGTTTGATTATTCTGCACTGCACGCCTGCCTGATGAACCTTGTCA
TCAATGCCGTGGATGCGGTGGAAGAAGCCGTTGCCGCGGGCACTCTGGAACACGGTGCCGGTACTGTAAGCATCCGCGTG
GTACAGGACAATGTCTGCGTCCGCTGGATCGTATGCGACAACGGCTCCGGCCTGCCTGCTGAGGCGGCGGGGCAGCTCCG
CAACGGCCGCTTTACTTCCAAACCAGCCGGTTCCGGTTTCGGCCTGATGGCAACGCGTAAATCAATGCGCGAGCAGAACG
GCGAACTGCACATCCGTGCCCGTGCCCGGGGCGGCACTGAAGCCGAACTTTCCCTCCCACTGTCCGGTAAGGCTTGCCAC
GAGTGA

Upstream 100 bases:

>100_bases
TATTCTGCGGTTTCCTTCCACCAGCTCTCTGCCCGCCGGGTCTGAGAGCGCTGCAACATAACATCTTTATCCCGCCTGCG
CGGAGCGATGGAACAGTACC

Downstream 100 bases:

>100_bases
CCTTGCGTGGCGGGACAATGCCGCACAACGCGCCTCACGCCGGATCAGGCCGTACGCGGCGTGCGTGTTGAGGGTGCAGG
GAGATCATCTCCCTGCCCGC

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MPDLTAAAESAPLSVMLVDDEPGILATMGPLVADMGYQVVTAQSGEAALQLAHDSRPPHVLLTDVRMPVMDGMALLRAFK
TAWPDTEVLMLTGHGDMQLAVESLRQGAGDFLTKPVNADVLEFALARAAERIALRGQVRRYTSQLESLVEQRTRELLEAE
RLAAMGETAGTMAHAIKNLAGGLEGAMFVLEKGLELDNREYLEQGWQMLRKDVGRLRDMAMNLLHLSRPAQPDMQPGDPL
GVARDVVRLLQSRAADAGALLRLEPSHQSENAKKSGSALFDYSALHACLMNLVINAVDAVEEAVAAGTLEHGAGTVSIRV
VQDNVCVRWIVCDNGSGLPAEAAGQLRNGRFTSKPAGSGFGLMATRKSMREQNGELHIRARARGGTEAELSLPLSGKACH
E

Sequences:

>Translated_401_residues
MPDLTAAAESAPLSVMLVDDEPGILATMGPLVADMGYQVVTAQSGEAALQLAHDSRPPHVLLTDVRMPVMDGMALLRAFK
TAWPDTEVLMLTGHGDMQLAVESLRQGAGDFLTKPVNADVLEFALARAAERIALRGQVRRYTSQLESLVEQRTRELLEAE
RLAAMGETAGTMAHAIKNLAGGLEGAMFVLEKGLELDNREYLEQGWQMLRKDVGRLRDMAMNLLHLSRPAQPDMQPGDPL
GVARDVVRLLQSRAADAGALLRLEPSHQSENAKKSGSALFDYSALHACLMNLVINAVDAVEEAVAAGTLEHGAGTVSIRV
VQDNVCVRWIVCDNGSGLPAEAAGQLRNGRFTSKPAGSGFGLMATRKSMREQNGELHIRARARGGTEAELSLPLSGKACH
E
>Mature_400_residues
PDLTAAAESAPLSVMLVDDEPGILATMGPLVADMGYQVVTAQSGEAALQLAHDSRPPHVLLTDVRMPVMDGMALLRAFKT
AWPDTEVLMLTGHGDMQLAVESLRQGAGDFLTKPVNADVLEFALARAAERIALRGQVRRYTSQLESLVEQRTRELLEAER
LAAMGETAGTMAHAIKNLAGGLEGAMFVLEKGLELDNREYLEQGWQMLRKDVGRLRDMAMNLLHLSRPAQPDMQPGDPLG
VARDVVRLLQSRAADAGALLRLEPSHQSENAKKSGSALFDYSALHACLMNLVINAVDAVEEAVAAGTLEHGAGTVSIRVV
QDNVCVRWIVCDNGSGLPAEAAGQLRNGRFTSKPAGSGFGLMATRKSMREQNGELHIRARARGGTEAELSLPLSGKACHE

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in the activation of nitrogen assimilatory genes such as glnA. NtrX is probably phosphorylated by ntrY and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=40, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788905, Length=122, Percent_Identity=39.344262295082, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=35.3448275862069, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=24.1803278688525, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=23.6, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 43040; Mature: 42909

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLTAAAESAPLSVMLVDDEPGILATMGPLVADMGYQVVTAQSGEAALQLAHDSRPPHV
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHEEECCCCCCCEE
LLTDVRMPVMDGMALLRAFKTAWPDTEVLMLTGHGDMQLAVESLRQGAGDFLTKPVNADV
EEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHH
LEFALARAAERIALRGQVRRYTSQLESLVEQRTRELLEAERLAAMGETAGTMAHAIKNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLEGAMFVLEKGLELDNREYLEQGWQMLRKDVGRLRDMAMNLLHLSRPAQPDMQPGDPL
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GVARDVVRLLQSRAADAGALLRLEPSHQSENAKKSGSALFDYSALHACLMNLVINAVDAV
HHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EEAVAAGTLEHGAGTVSIRVVQDNVCVRWIVCDNGSGLPAEAAGQLRNGRFTSKPAGSGF
HHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCC
GLMATRKSMREQNGELHIRARARGGTEAELSLPLSGKACHE
CHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
PDLTAAAESAPLSVMLVDDEPGILATMGPLVADMGYQVVTAQSGEAALQLAHDSRPPHV
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHEEECCCCCCCEE
LLTDVRMPVMDGMALLRAFKTAWPDTEVLMLTGHGDMQLAVESLRQGAGDFLTKPVNADV
EEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHH
LEFALARAAERIALRGQVRRYTSQLESLVEQRTRELLEAERLAAMGETAGTMAHAIKNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLEGAMFVLEKGLELDNREYLEQGWQMLRKDVGRLRDMAMNLLHLSRPAQPDMQPGDPL
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GVARDVVRLLQSRAADAGALLRLEPSHQSENAKKSGSALFDYSALHACLMNLVINAVDAV
HHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EEAVAAGTLEHGAGTVSIRVVQDNVCVRWIVCDNGSGLPAEAAGQLRNGRFTSKPAGSGF
HHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCC
GLMATRKSMREQNGELHIRARARGGTEAELSLPLSGKACHE
CHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]