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The map label for this gene is rffG [C]

Identifier: 78358730

GI number: 78358730

Start: 3651000

End: 3651959

Strand: Direct

Name: rffG [C]

Synonym: Dde_3691

Alternate gene names: 78358730

Gene position: 3651000-3651959 (Clockwise)

Preceding gene: 78358729

Following gene: 78358731

Centisome position: 97.88

GC content: 60.52

Gene sequence:

>960_bases
ATGGCAAACTATCTTGTAACCGGCATTGCCGGATTCATCGGTTCCGCCGTGGCGCGCGCCCTGCTGCGGCAGGGACATCA
GGTCACCGGCGTGGATAACCTGACAACAGGATACCGCGACAATGTTCCCGCGGGTGCCGCCTTTATCAAGGCAGACTGTC
AGGACGCCGCCCTGTACGATACCGTCCTGCCGCGCACCCCCTTTGACGCGATTTTTCACATAGCCGGACAAAGCAGCGGC
GAAGTGAGTTTTGACGATCCCGCATATGACCTGCGCACCAACACTGAATCGACGCTGCATCTGCTGCGGTTTGCCCGCCG
CACCGGCTGCACGCGGCTCATATATGCCAGCACCATGTCGGTATACGGCTGCCAGCCGGACGAACCCGTGCATGAAACAG
CCCCCGCAGCACCGCTTTCATTCTACGGTGTGGGCAAACTGGCCAGCGAGCACTACCTGCGCCTGCATGAACAGTTCGGC
ATCCGTTCCACCGCGCTGCGCCTGTTCAATGTGTACGGCCACGGGCAGAACATGGACAACATGCGTCAGGGCATGGTTTC
CATTTTCATGGCCATGATGCTGCGCAACGGGCACATTCATGTGAAAGGCAGCCCGGAAAGATACCGGGACTTTGTGCACA
TTGACGACGTGGTACGCGCCTTTCTGCTCTGTCTCGGGCAGCAGCGCTCGCACGGCGAAGTGATCAACATCGCCGGCAGC
GGCCGTGTTACCGTGGGGCAGCTGGTGGAAGAACTGCGTGCTCTGCATCCGGCACCTGTCACCGTGGAGTTTTCCGGCTG
CACGGCAGGAGACATGCACGGCATACATGCAGACAAAGACAAAGCCCGCACAGTACTGGGCTATACGCCGCAGGTTTCGC
TGCGGCAGGGGCTGGAAGACATGTACCGGCGCACCGCACCTCTGCTGACCCGGCACCACGGGGCAGAAAACGCATCCTGA

Upstream 100 bases:

>100_bases
AGGACCACCTGCTGCAGCTGTTGCAGTGCGGCGGGGCATAACCCGTCCCAAAGCAGACAGACCACGTTCCGGCCCGTGCC
GGACACGGAGCATACAGACA

Downstream 100 bases:

>100_bases
ACGCAGGGAGACGCCATGACCAGCGCAGAACAGCCTGCCATGCACAGCGGCGGCCAGACCGGCTGCAACCATATTCATCC
CGCAGCCACCGTGGCACAGG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MANYLVTGIAGFIGSAVARALLRQGHQVTGVDNLTTGYRDNVPAGAAFIKADCQDAALYDTVLPRTPFDAIFHIAGQSSG
EVSFDDPAYDLRTNTESTLHLLRFARRTGCTRLIYASTMSVYGCQPDEPVHETAPAAPLSFYGVGKLASEHYLRLHEQFG
IRSTALRLFNVYGHGQNMDNMRQGMVSIFMAMMLRNGHIHVKGSPERYRDFVHIDDVVRAFLLCLGQQRSHGEVINIAGS
GRVTVGQLVEELRALHPAPVTVEFSGCTAGDMHGIHADKDKARTVLGYTPQVSLRQGLEDMYRRTAPLLTRHHGAENAS

Sequences:

>Translated_319_residues
MANYLVTGIAGFIGSAVARALLRQGHQVTGVDNLTTGYRDNVPAGAAFIKADCQDAALYDTVLPRTPFDAIFHIAGQSSG
EVSFDDPAYDLRTNTESTLHLLRFARRTGCTRLIYASTMSVYGCQPDEPVHETAPAAPLSFYGVGKLASEHYLRLHEQFG
IRSTALRLFNVYGHGQNMDNMRQGMVSIFMAMMLRNGHIHVKGSPERYRDFVHIDDVVRAFLLCLGQQRSHGEVINIAGS
GRVTVGQLVEELRALHPAPVTVEFSGCTAGDMHGIHADKDKARTVLGYTPQVSLRQGLEDMYRRTAPLLTRHHGAENAS
>Mature_318_residues
ANYLVTGIAGFIGSAVARALLRQGHQVTGVDNLTTGYRDNVPAGAAFIKADCQDAALYDTVLPRTPFDAIFHIAGQSSGE
VSFDDPAYDLRTNTESTLHLLRFARRTGCTRLIYASTMSVYGCQPDEPVHETAPAAPLSFYGVGKLASEHYLRLHEQFGI
RSTALRLFNVYGHGQNMDNMRQGMVSIFMAMMLRNGHIHVKGSPERYRDFVHIDDVVRAFLLCLGQQRSHGEVINIAGSG
RVTVGQLVEELRALHPAPVTVEFSGCTAGDMHGIHADKDKARTVLGYTPQVSLRQGLEDMYRRTAPLLTRHHGAENAS

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=301, Percent_Identity=30.2325581395349, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI7657641, Length=325, Percent_Identity=25.8461538461538, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI56237023, Length=330, Percent_Identity=22.4242424242424, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI56118217, Length=330, Percent_Identity=22.4242424242424, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI189083684, Length=330, Percent_Identity=22.4242424242424, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI48994969, Length=331, Percent_Identity=28.7009063444109, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=26.7267267267267, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788353, Length=329, Percent_Identity=26.4437689969605, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788366, Length=355, Percent_Identity=24.2253521126761, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=303, Percent_Identity=29.042904290429, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17507723, Length=339, Percent_Identity=25.0737463126844, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=22.8486646884273, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356223, Length=302, Percent_Identity=30.4635761589404, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34998; Mature: 34867

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYLVTGIAGFIGSAVARALLRQGHQVTGVDNLTTGYRDNVPAGAAFIKADCQDAALYD
CCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHEEECCCCCHHHHH
TVLPRTPFDAIFHIAGQSSGEVSFDDPAYDLRTNTESTLHLLRFARRTGCTRLIYASTMS
HHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHH
VYGCQPDEPVHETAPAAPLSFYGVGKLASEHYLRLHEQFGIRSTALRLFNVYGHGQNMDN
HCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
MRQGMVSIFMAMMLRNGHIHVKGSPERYRDFVHIDDVVRAFLLCLGQQRSHGEVINIAGS
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GRVTVGQLVEELRALHPAPVTVEFSGCTAGDMHGIHADKDKARTVLGYTPQVSLRQGLED
CCEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHCEEECCCCCHHHHHHHHH
MYRRTAPLLTRHHGAENAS
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANYLVTGIAGFIGSAVARALLRQGHQVTGVDNLTTGYRDNVPAGAAFIKADCQDAALYD
CCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHEEECCCCCHHHHH
TVLPRTPFDAIFHIAGQSSGEVSFDDPAYDLRTNTESTLHLLRFARRTGCTRLIYASTMS
HHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHH
VYGCQPDEPVHETAPAAPLSFYGVGKLASEHYLRLHEQFGIRSTALRLFNVYGHGQNMDN
HCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHH
MRQGMVSIFMAMMLRNGHIHVKGSPERYRDFVHIDDVVRAFLLCLGQQRSHGEVINIAGS
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GRVTVGQLVEELRALHPAPVTVEFSGCTAGDMHGIHADKDKARTVLGYTPQVSLRQGLED
CCEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHCEEECCCCCHHHHHHHHH
MYRRTAPLLTRHHGAENAS
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]