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The map label for this gene is kdsB [H]

Identifier: 78358726

GI number: 78358726

Start: 3647931

End: 3648704

Strand: Direct

Name: kdsB [H]

Synonym: Dde_3687

Alternate gene names: 78358726

Gene position: 3647931-3648704 (Clockwise)

Preceding gene: 78358725

Following gene: 78358727

Centisome position: 97.79

GC content: 59.04

Gene sequence:

>774_bases
ATGAACATTATCGCCATAATACCCGCCCGCATGGGTTCCAGCCGGTTTCCCGGCAAACCGCTGGCCGACATCCACGGCGT
GCCCATGGTGGGCCACGTGGCACTGCGCACCGCCATGGCTCCCGCTGTCAGCGAAACATGGATAGCCACCTGCGACGAAG
AAATCATGGAATATGCCCGCAAGGCCGGCATCAAGGCGGTCATGACGGCAGACACCCATGAACGCTGCACGGACCGCACT
GCGGAAGCCATGCTGAAAATTGAAGAAATGACCGGTAAAAGCGTGGATATCGTCGTCATGGTGCAGGGAGATGAGCCCAT
GGTCACTCCGGACATGATAGACGCCGCCATAGCCCCCATGCTGGAAGACGCCTCGGTGAACGTGACCAACCTGATGGCCG
ACATGGAAACAGAAGCGGAATTTGAAGACCCCAATGAAGTCAAGGTGGTGACAGACCTGCACGGTGATGCGCTGTACTTT
TCGCGCGAGCCTGTGCCCTCGCGCAAAAAGGGCGTGCTCAACGTGCCCATGCGCAAACAGGTCTGCGTCATCCCGTTCCG
CCGCGATTATCTGCTGCGCTTCAACAACCTGCCTGAAACCCCGCTGGAACGCATCGAGTCGGTGGACATGATGCGCATTC
TCGAACACGGCGAAAAAGTACGCATGGTGCCGTTCTCCGGCAGAACCCTGAGCGTGGACACCCCGCAGGATCTGGAAAGG
GCCCGCGCCATGATGCAGCAGGATACTCTGCGCAGAGACTACACCGGAGCCTGA

Upstream 100 bases:

>100_bases
TATCCCTGATGATTTCTTTCTGATGATTTATTTCTGACAGCCCGCGGCTGCCGCAGCGGCAGTACGCGGGGCACAGCAAG
AACACCGCAAGGACACAGCA

Downstream 100 bases:

>100_bases
CCCATGCTGCCGCGTCCTGAAACGCTCTGCCTGCGCGCTGCGCTGCGCGACAACGCCGAAGAACTGTGGACATGGCTTGC
AGCCGTGCCGCCCACCGCAG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNIIAIIPARMGSSRFPGKPLADIHGVPMVGHVALRTAMAPAVSETWIATCDEEIMEYARKAGIKAVMTADTHERCTDRT
AEAMLKIEEMTGKSVDIVVMVQGDEPMVTPDMIDAAIAPMLEDASVNVTNLMADMETEAEFEDPNEVKVVTDLHGDALYF
SREPVPSRKKGVLNVPMRKQVCVIPFRRDYLLRFNNLPETPLERIESVDMMRILEHGEKVRMVPFSGRTLSVDTPQDLER
ARAMMQQDTLRRDYTGA

Sequences:

>Translated_257_residues
MNIIAIIPARMGSSRFPGKPLADIHGVPMVGHVALRTAMAPAVSETWIATCDEEIMEYARKAGIKAVMTADTHERCTDRT
AEAMLKIEEMTGKSVDIVVMVQGDEPMVTPDMIDAAIAPMLEDASVNVTNLMADMETEAEFEDPNEVKVVTDLHGDALYF
SREPVPSRKKGVLNVPMRKQVCVIPFRRDYLLRFNNLPETPLERIESVDMMRILEHGEKVRMVPFSGRTLSVDTPQDLER
ARAMMQQDTLRRDYTGA
>Mature_257_residues
MNIIAIIPARMGSSRFPGKPLADIHGVPMVGHVALRTAMAPAVSETWIATCDEEIMEYARKAGIKAVMTADTHERCTDRT
AEAMLKIEEMTGKSVDIVVMVQGDEPMVTPDMIDAAIAPMLEDASVNVTNLMADMETEAEFEDPNEVKVVTDLHGDALYF
SREPVPSRKKGVLNVPMRKQVCVIPFRRDYLLRFNNLPETPLERIESVDMMRILEHGEKVRMVPFSGRTLSVDTPQDLER
ARAMMQQDTLRRDYTGA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=257, Percent_Identity=36.5758754863813, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28750; Mature: 28750

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
7.8 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
7.8 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIAIIPARMGSSRFPGKPLADIHGVPMVGHVALRTAMAPAVSETWIATCDEEIMEYAR
CCEEEEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
KAGIKAVMTADTHERCTDRTAEAMLKIEEMTGKSVDIVVMVQGDEPMVTPDMIDAAIAPM
HCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHH
LEDASVNVTNLMADMETEAEFEDPNEVKVVTDLHGDALYFSREPVPSRKKGVLNVPMRKQ
HCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCC
VCVIPFRRDYLLRFNNLPETPLERIESVDMMRILEHGEKVRMVPFSGRTLSVDTPQDLER
EEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCHHHHHH
ARAMMQQDTLRRDYTGA
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNIIAIIPARMGSSRFPGKPLADIHGVPMVGHVALRTAMAPAVSETWIATCDEEIMEYAR
CCEEEEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
KAGIKAVMTADTHERCTDRTAEAMLKIEEMTGKSVDIVVMVQGDEPMVTPDMIDAAIAPM
HCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHH
LEDASVNVTNLMADMETEAEFEDPNEVKVVTDLHGDALYFSREPVPSRKKGVLNVPMRKQ
HCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCC
VCVIPFRRDYLLRFNNLPETPLERIESVDMMRILEHGEKVRMVPFSGRTLSVDTPQDLER
EEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCHHHHHH
ARAMMQQDTLRRDYTGA
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA