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The map label for this gene is ttdA [C]

Identifier: 78358678

GI number: 78358678

Start: 3602647

End: 3603486

Strand: Reverse

Name: ttdA [C]

Synonym: Dde_3639

Alternate gene names: 78358678

Gene position: 3603486-3602647 (Counterclockwise)

Preceding gene: 78358679

Following gene: 78358677

Centisome position: 96.6

GC content: 62.02

Gene sequence:

>840_bases
ATGAGGATAATAGAAGCGTCCGCTGTGCACGCTGCGGTACGGCAGATGATTCTGGCCGCCAACAGGGTGTTGGGCGATGA
TGTGTACGCCGCATTGAAAAGCAGCATGGAGAGTGAGACTTCGGCTTCGGGCAGAGAGGTGCTGCGTCAGCTGCTGGAAA
ACGCCGACCTTGCCGCATCCGGCGGACTGGCATTGTGTCAGGACACCGGCGCTGCGGTCTTTTTTGTGGAAATGGGCGAA
GACGTGCGTCTGGGTGGCGGTTCGCTGCAGCATGTGCTGAACAGCGCCATGGCGCAGGCGTATGAAGAAGGCTGCCTGCG
CAAGTCCATGTGCCATCCGCTTACGCGCTGCAACACCGGCGACAACCGTCCCGCCATCGTGCATACGGAACTGGTGGAAG
GCGACCGGCTGACCATACGCTATATGGCCAAAGGCGGCGGCAGCGAAAACATGTCGCGCTGCACCATGCTGACCCCCGCG
CAGGGCTGGCAGGGTATAAAGGAATTTGTGGTACGCCGCATGGCCGAAGCCGGTCCCAACCCCTGCCCGCCCACCATCGT
GGGAGTGGGTATAGGCGGTACGTTCGACCTTGCTCCCGCGCTGGCAAAGCGGGCGCTGTTCCGCAGACTGGACGACGTGC
ACCCCGATGCGGAAGTGGCCGCCATGGAAACCGAGCTGCTGGATGCGCTCAACGCGCTGGGCATCGGTCCCATGGGCCTT
GGCGGACGCACGACATGTCTGGCTGTGAAAATTGCCCTGCATCCCTGCCATATTGCCAGCCTGCCTGTGGCGGTGAATGT
GCAGTGCCATTCGGCGCGGCACAGAGAGGTGATTCTCTGA

Upstream 100 bases:

>100_bases
TTTAAGACAGGGGTTGCGCGCGCGGACGGGGCCGTGTCCGGTGCCGTATGCCGCCGCGCGGGCCGGTATGTCTGCAATAT
GTCGGAAAAGGTGTGACCAT

Downstream 100 bases:

>100_bases
TGGCTACCTGGCATCTTACCACACCACTCAGGTCTGAGGATGTGCTGCAACTGCGCGCCGGTGATGTCGTGCTGCTTTCG
GGCGATATATATACAGCCCG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRIIEASAVHAAVRQMILAANRVLGDDVYAALKSSMESETSASGREVLRQLLENADLAASGGLALCQDTGAAVFFVEMGE
DVRLGGGSLQHVLNSAMAQAYEEGCLRKSMCHPLTRCNTGDNRPAIVHTELVEGDRLTIRYMAKGGGSENMSRCTMLTPA
QGWQGIKEFVVRRMAEAGPNPCPPTIVGVGIGGTFDLAPALAKRALFRRLDDVHPDAEVAAMETELLDALNALGIGPMGL
GGRTTCLAVKIALHPCHIASLPVAVNVQCHSARHREVIL

Sequences:

>Translated_279_residues
MRIIEASAVHAAVRQMILAANRVLGDDVYAALKSSMESETSASGREVLRQLLENADLAASGGLALCQDTGAAVFFVEMGE
DVRLGGGSLQHVLNSAMAQAYEEGCLRKSMCHPLTRCNTGDNRPAIVHTELVEGDRLTIRYMAKGGGSENMSRCTMLTPA
QGWQGIKEFVVRRMAEAGPNPCPPTIVGVGIGGTFDLAPALAKRALFRRLDDVHPDAEVAAMETELLDALNALGIGPMGL
GGRTTCLAVKIALHPCHIASLPVAVNVQCHSARHREVIL
>Mature_279_residues
MRIIEASAVHAAVRQMILAANRVLGDDVYAALKSSMESETSASGREVLRQLLENADLAASGGLALCQDTGAAVFFVEMGE
DVRLGGGSLQHVLNSAMAQAYEEGCLRKSMCHPLTRCNTGDNRPAIVHTELVEGDRLTIRYMAKGGGSENMSRCTMLTPA
QGWQGIKEFVVRRMAEAGPNPCPPTIVGVGIGGTFDLAPALAKRALFRRLDDVHPDAEVAAMETELLDALNALGIGPMGL
GGRTTCLAVKIALHPCHIASLPVAVNVQCHSARHREVIL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=252, Percent_Identity=32.5396825396825, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1787897, Length=254, Percent_Identity=31.8897637795276, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1790564, Length=254, Percent_Identity=31.8897637795276, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29620; Mature: 29620

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIEASAVHAAVRQMILAANRVLGDDVYAALKSSMESETSASGREVLRQLLENADLAAS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GGLALCQDTGAAVFFVEMGEDVRLGGGSLQHVLNSAMAQAYEEGCLRKSMCHPLTRCNTG
CCEEEEECCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DNRPAIVHTELVEGDRLTIRYMAKGGGSENMSRCTMLTPAQGWQGIKEFVVRRMAEAGPN
CCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCC
PCPPTIVGVGIGGTFDLAPALAKRALFRRLDDVHPDAEVAAMETELLDALNALGIGPMGL
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
GGRTTCLAVKIALHPCHIASLPVAVNVQCHSARHREVIL
CCCCEEEEEEEEECCHHHCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRIIEASAVHAAVRQMILAANRVLGDDVYAALKSSMESETSASGREVLRQLLENADLAAS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GGLALCQDTGAAVFFVEMGEDVRLGGGSLQHVLNSAMAQAYEEGCLRKSMCHPLTRCNTG
CCEEEEECCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DNRPAIVHTELVEGDRLTIRYMAKGGGSENMSRCTMLTPAQGWQGIKEFVVRRMAEAGPN
CCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCC
PCPPTIVGVGIGGTFDLAPALAKRALFRRLDDVHPDAEVAAMETELLDALNALGIGPMGL
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
GGRTTCLAVKIALHPCHIASLPVAVNVQCHSARHREVIL
CCCCEEEEEEEEECCHHHCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]