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The map label for this gene is 78358491

Identifier: 78358491

GI number: 78358491

Start: 3413313

End: 3414488

Strand: Direct

Name: 78358491

Synonym: Dde_3452

Alternate gene names: NA

Gene position: 3413313-3414488 (Clockwise)

Preceding gene: 78358490

Following gene: 78358492

Centisome position: 91.5

GC content: 63.1

Gene sequence:

>1176_bases
ATGCTGAACAAGCCCAGAATGCTCACCCCCGGCCCCACGCCCATACCCGCCGCAGTGCGGCTGGCCATGGCGCAGGACAT
GATCCACCACCGCAAACCCGCGTTCAAAGCCGTCATGGCCGAAACCCAGCGGTTGCTCAGACCGCTTTTCGGCACTGCGC
AGCCCGTACTGCCGCTGTCATGTTCCGGCACGGGCGCCATGACTGCCGCGGTCACCAACCTGTTTTCCGCCGGTGAAAAG
GTGGTGGTGGTGGAAGGCGGCAAATTCGGCCAGCGCTGGACAGAAATTGCCCGCTCGCACGGTCTTGTACCCGTGGTCAT
CGAGGTGCCCTGGGGCAGCGCGGTAACCGCGCAGGCCGTCAAACAGACGCTGGAACAGCACGGCGATGCGGCGGGTGTGC
TGGTGCAGTGCTCGGAAACATCCACCGGTGTCATGCATCCCGTCCGCGAGATAGCCGCCGTCACGCGCTCCGCCGAAACA
CTGCTGGTGGTGGACGGCATTTCCTCGGTGGGACTTTCGCCCTGTCCCATGGACGAATGGGGAGTTGACTGTCTGCTCAC
CGGCTCGCAAAAAGGACTGATGCTGCCCCCCGGTCTGGCGCTCATCGCCCTGTCCGAGCGGGCCTGGGCCCGTACCGCCA
CGGTGACGCCCTCATGCTTTTACTTCAACCTGCGGGCTGAACGTAAAAATGCCGAAGCCGACCAGACGCTGTTCACAACG
CCTGTCAGCCTGATAATCGGACTGCGCGAAAGTCTGCGCATGTACGAAGAAACAGGGCTGGAAGAGGTTTTCCGCAAGCA
GTGGGCGCTCACACAGATGGTGCGCACCGGTGTAAGCGCCATGGGGCTTGCTCCCTTTGTGGCCGCGGACTACGGCTGGG
GGCTGACCAGCATAGCACTGCCCGGAGGAATCGACGGCACTGCGGTGCTGGCCCATGCCGCGCAGCATTACGGCGTTATC
ATGGCCGGAGGACAGGACCACCTGAAGGGCCGTATCATACGCATGGGACACATGGGCTGGGTGGACTGGGGCGACATAGC
CGCCGGCCTGCACGCACTGGCAGAAAGCTACCGCGCCTGCGGGGGCTACATAGGCTGCCGCGATTATATCGAACAGGCCT
TGCAAGCCTACAACGAGGCATTACTCTCCTACGCAGAGAACAACCCGTTCGCCTGA

Upstream 100 bases:

>100_bases
CTGTTCATCCGGCCATGCCGGAAACGAATTATCTGAAAACATTCACCGTGCGGGTGAACCGCACAAGCTGATTCAGTACC
TACCTGAACCGGAGAATCTC

Downstream 100 bases:

>100_bases
GACGAAAAAACGGCGGTGCGGCAGCGCGTATGACGCTGCCGCAGAAACGGCATCAGGAGTCATCGCATGTCAGAAGCACA
GGAAAAAAGCGGCTGCGGCT

Product: class V aminotransferase

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLNKPRMLTPGPTPIPAAVRLAMAQDMIHHRKPAFKAVMAETQRLLRPLFGTAQPVLPLSCSGTGAMTAAVTNLFSAGEK
VVVVEGGKFGQRWTEIARSHGLVPVVIEVPWGSAVTAQAVKQTLEQHGDAAGVLVQCSETSTGVMHPVREIAAVTRSAET
LLVVDGISSVGLSPCPMDEWGVDCLLTGSQKGLMLPPGLALIALSERAWARTATVTPSCFYFNLRAERKNAEADQTLFTT
PVSLIIGLRESLRMYEETGLEEVFRKQWALTQMVRTGVSAMGLAPFVAADYGWGLTSIALPGGIDGTAVLAHAAQHYGVI
MAGGQDHLKGRIIRMGHMGWVDWGDIAAGLHALAESYRACGGYIGCRDYIEQALQAYNEALLSYAENNPFA

Sequences:

>Translated_391_residues
MLNKPRMLTPGPTPIPAAVRLAMAQDMIHHRKPAFKAVMAETQRLLRPLFGTAQPVLPLSCSGTGAMTAAVTNLFSAGEK
VVVVEGGKFGQRWTEIARSHGLVPVVIEVPWGSAVTAQAVKQTLEQHGDAAGVLVQCSETSTGVMHPVREIAAVTRSAET
LLVVDGISSVGLSPCPMDEWGVDCLLTGSQKGLMLPPGLALIALSERAWARTATVTPSCFYFNLRAERKNAEADQTLFTT
PVSLIIGLRESLRMYEETGLEEVFRKQWALTQMVRTGVSAMGLAPFVAADYGWGLTSIALPGGIDGTAVLAHAAQHYGVI
MAGGQDHLKGRIIRMGHMGWVDWGDIAAGLHALAESYRACGGYIGCRDYIEQALQAYNEALLSYAENNPFA
>Mature_391_residues
MLNKPRMLTPGPTPIPAAVRLAMAQDMIHHRKPAFKAVMAETQRLLRPLFGTAQPVLPLSCSGTGAMTAAVTNLFSAGEK
VVVVEGGKFGQRWTEIARSHGLVPVVIEVPWGSAVTAQAVKQTLEQHGDAAGVLVQCSETSTGVMHPVREIAAVTRSAET
LLVVDGISSVGLSPCPMDEWGVDCLLTGSQKGLMLPPGLALIALSERAWARTATVTPSCFYFNLRAERKNAEADQTLFTT
PVSLIIGLRESLRMYEETGLEEVFRKQWALTQMVRTGVSAMGLAPFVAADYGWGLTSIALPGGIDGTAVLAHAAQHYGVI
MAGGQDHLKGRIIRMGHMGWVDWGDIAAGLHALAESYRACGGYIGCRDYIEQALQAYNEALLSYAENNPFA

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=343, Percent_Identity=30.0291545189504, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17536281, Length=350, Percent_Identity=30, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321079, Length=362, Percent_Identity=29.0055248618785, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17530823, Length=343, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41840; Mature: 41840

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKPRMLTPGPTPIPAAVRLAMAQDMIHHRKPAFKAVMAETQRLLRPLFGTAQPVLPLS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
CSGTGAMTAAVTNLFSAGEKVVVVEGGKFGQRWTEIARSHGLVPVVIEVPWGSAVTAQAV
CCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
KQTLEQHGDAAGVLVQCSETSTGVMHPVREIAAVTRSAETLLVVDGISSVGLSPCPMDEW
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCCCCC
GVDCLLTGSQKGLMLPPGLALIALSERAWARTATVTPSCFYFNLRAERKNAEADQTLFTT
CCCEEEECCCCCCCCCCCCEEEEECCCHHHEEEECCCCEEEEEEEECCCCCCCCCHHHHH
PVSLIIGLRESLRMYEETGLEEVFRKQWALTQMVRTGVSAMGLAPFVAADYGWGLTSIAL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHCCCCCHHHEEC
PGGIDGTAVLAHAAQHYGVIMAGGQDHLKGRIIRMGHMGWVDWGDIAAGLHALAESYRAC
CCCCCHHHHHHHHHHHCCEEEECCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
GGYIGCRDYIEQALQAYNEALLSYAENNPFA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNKPRMLTPGPTPIPAAVRLAMAQDMIHHRKPAFKAVMAETQRLLRPLFGTAQPVLPLS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
CSGTGAMTAAVTNLFSAGEKVVVVEGGKFGQRWTEIARSHGLVPVVIEVPWGSAVTAQAV
CCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
KQTLEQHGDAAGVLVQCSETSTGVMHPVREIAAVTRSAETLLVVDGISSVGLSPCPMDEW
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCCCCC
GVDCLLTGSQKGLMLPPGLALIALSERAWARTATVTPSCFYFNLRAERKNAEADQTLFTT
CCCEEEECCCCCCCCCCCCEEEEECCCHHHEEEECCCCEEEEEEEECCCCCCCCCHHHHH
PVSLIIGLRESLRMYEETGLEEVFRKQWALTQMVRTGVSAMGLAPFVAADYGWGLTSIAL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHCCCCCHHHEEC
PGGIDGTAVLAHAAQHYGVIMAGGQDHLKGRIIRMGHMGWVDWGDIAAGLHALAESYRAC
CCCCCHHHHHHHHHHHCCEEEECCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
GGYIGCRDYIEQALQAYNEALLSYAENNPFA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]