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The map label for this gene is htpX [H]

Identifier: 78358458

GI number: 78358458

Start: 3382058

End: 3383023

Strand: Direct

Name: htpX [H]

Synonym: Dde_3419

Alternate gene names: 78358458

Gene position: 3382058-3383023 (Clockwise)

Preceding gene: 78358457

Following gene: 78358459

Centisome position: 90.67

GC content: 68.12

Gene sequence:

>966_bases
ATGACCCGTCATCATCCCAGTGACCCGCGCGCGGCGTTGTTGCAACACCGCTGGCTCAACCGCCTGCAGACCGGGCTGTT
GGTCCTGACCCTGGTCGGGATCGCAGCCGCCGCAGGAAGCCTGCTGTTCGGGGAAAGCGGCCTGTGGCTCGCGCTGTTTG
CCGTTGCAGGCACGCTGCTGCTGGAACCGGCAGCCGCATCTGCCTTGACCTTGCGCCTATACCGCGCCCGGGCGCTGCAC
CCGCACGAAGCCCCGGAAATTTGGGCCCTGTTGCACGAGCTGTCCGTCCGTGCCGGTTTGCCCGCAACGCCGGTGCCGCA
CTACGTGCCCAGTGCCGTCGTCAACGCCTTCGCCACCGGATCGAAGCAGGAGGCATCGATCGCCCTCACGGATGGCCTGC
TGCGCCGCCTGAGCCCACGCGAGCTGGCGGGTGTGCTCGCGCACGAGATCGCGCACATCGCCAATGAGGATCTGCGCGTC
ATGGGGCTGGCGGATTCCGTCAGTCGCCTCACGCGCCTACTGGCCCTTGTGGGACAGATCGCGATCCTGCTGAGCCTGCC
CGCGCTGCTGGTTGGCGCGGCGGAGGTCTATTGGCCTGGTTTATTGTTATTGGCCGCATCGCCCCAGCTGGCCCTGCTCG
CACAGCTCGGCTTGTCTCGCGTGCGTGAGTTCGACGCTGACCGCCTCGCGGTGGAACTGACCGGCGACCCGCAAGGGCTG
GCGTCCGCGCTGGCGAAGATCGAGCGGGTCAGTCGCTCCTGGCGTGCCTGGCTGTGGCCGGGATGGGGCAATCCCGAGCC
CTCCTGGTTGCGCACGCATCCGGCCACGCAAGAGCGCATCTCACGCCTGCTGACGTTGGCGCCCAGGCCAGCATCAGCGT
TGCCGTTTCACGAGATCCATTCCTTGCCGGAATCCGCTGTGACGCTGCGCCCCCCGCGCTGGCGCCCGAGCGGGCTATGG
CGCTGA

Upstream 100 bases:

>100_bases
CCTGGCAAGATCGCCGCGCTTGCAGACGCCACGCTGGCGCTTGGTTCCACTTACTGGCTGCTGCGCGAGCGCGACGACCG
CGCCGCCGAGACATCTGAGC

Downstream 100 bases:

>100_bases
TTGTCTATCAACAGGAGACTTCTCATGGCCTACCCCGACCCGTACGCGCGCCCGCCACAGGACCACTTTATCCGTCGCTG
GCTCTTCATCACCGCCTGCA

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTRHHPSDPRAALLQHRWLNRLQTGLLVLTLVGIAAAAGSLLFGESGLWLALFAVAGTLLLEPAAASALTLRLYRARALH
PHEAPEIWALLHELSVRAGLPATPVPHYVPSAVVNAFATGSKQEASIALTDGLLRRLSPRELAGVLAHEIAHIANEDLRV
MGLADSVSRLTRLLALVGQIAILLSLPALLVGAAEVYWPGLLLLAASPQLALLAQLGLSRVREFDADRLAVELTGDPQGL
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPRPASALPFHEIHSLPESAVTLRPPRWRPSGLW
R

Sequences:

>Translated_321_residues
MTRHHPSDPRAALLQHRWLNRLQTGLLVLTLVGIAAAAGSLLFGESGLWLALFAVAGTLLLEPAAASALTLRLYRARALH
PHEAPEIWALLHELSVRAGLPATPVPHYVPSAVVNAFATGSKQEASIALTDGLLRRLSPRELAGVLAHEIAHIANEDLRV
MGLADSVSRLTRLLALVGQIAILLSLPALLVGAAEVYWPGLLLLAASPQLALLAQLGLSRVREFDADRLAVELTGDPQGL
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPRPASALPFHEIHSLPESAVTLRPPRWRPSGLW
R
>Mature_320_residues
TRHHPSDPRAALLQHRWLNRLQTGLLVLTLVGIAAAAGSLLFGESGLWLALFAVAGTLLLEPAAASALTLRLYRARALHP
HEAPEIWALLHELSVRAGLPATPVPHYVPSAVVNAFATGSKQEASIALTDGLLRRLSPRELAGVLAHEIAHIANEDLRVM
GLADSVSRLTRLLALVGQIAILLSLPALLVGAAEVYWPGLLLLAASPQLALLAQLGLSRVREFDADRLAVELTGDPQGLA
SALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPRPASALPFHEIHSLPESAVTLRPPRWRPSGLWR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=298, Percent_Identity=28.1879194630872, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 34827; Mature: 34696

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRHHPSDPRAALLQHRWLNRLQTGLLVLTLVGIAAAAGSLLFGESGLWLALFAVAGTLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LEPAAASALTLRLYRARALHPHEAPEIWALLHELSVRAGLPATPVPHYVPSAVVNAFATG
HCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
SKQEASIALTDGLLRRLSPRELAGVLAHEIAHIANEDLRVMGLADSVSRLTRLLALVGQI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
AILLSLPALLVGAAEVYWPGLLLLAASPQLALLAQLGLSRVREFDADRLAVELTGDPQGL
HHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHH
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPRPASALPFHEIH
HHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
SLPESAVTLRPPRWRPSGLWR
CCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
TRHHPSDPRAALLQHRWLNRLQTGLLVLTLVGIAAAAGSLLFGESGLWLALFAVAGTLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LEPAAASALTLRLYRARALHPHEAPEIWALLHELSVRAGLPATPVPHYVPSAVVNAFATG
HCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
SKQEASIALTDGLLRRLSPRELAGVLAHEIAHIANEDLRVMGLADSVSRLTRLLALVGQI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
AILLSLPALLVGAAEVYWPGLLLLAASPQLALLAQLGLSRVREFDADRLAVELTGDPQGL
HHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHH
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPRPASALPFHEIH
HHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
SLPESAVTLRPPRWRPSGLWR
CCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA