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The map label for this gene is lutB [H]

Identifier: 78358285

GI number: 78358285

Start: 3240864

End: 3243005

Strand: Direct

Name: lutB [H]

Synonym: Dde_3245

Alternate gene names: 78358285

Gene position: 3240864-3243005 (Clockwise)

Preceding gene: 78358284

Following gene: 78358286

Centisome position: 86.88

GC content: 58.54

Gene sequence:

>2142_bases
ATGCAGAACGCGAAGAATCTGAAAGAATACCGCGCCGAACTGCGCGAATCGCTGGATAACGATTTTCTGCGCTCCACCAT
GGACAAATTTGCCGTTGCCTACCCCGTGGGCCGCGCCAACGCGTTCAAGGGCATGGACGTGCAGTCGCTCATCGCCGAAG
TGGCTGACGCCAAAGACGCCGCAGCAAAGCAGATGGATCAGCTGTACGCCCAGTTCAAGGCCGAAGCTGAAAAACGCGGC
GTCAAGGTGCATCTGGCCAAGACAGCTCAGGAAGCCAACGAAATCATCGCCCAGATCGCACGCGATGCCGGTGTGAAAAA
AATTGTCAAATCCAAATCCATGACCAGTGAAGAAACTCAGTTCAACCATCAGGTTGAAAATGAGTTTGAAGTGGTGGAAA
CCGACCTTGGCGAATGGATCATCCAGCTGCGCCACGAAGGTCCCACTCACATGGTTATGCCCGCAATCCACCTTTCGCGT
AATCAGGTGGCCGATCTGTTCAGCGACGTGACCAAGCAGAAGCAGGACAACGATCCGCAAAAGCTGACCAAAGTGGCCCG
CCGTGAACTGCGCAAAGAATACGCCACCGCCGAAATGGGCGTCACCGGCGCCAACTTCTGTGTGGCTTCCACCGGCACCA
TCGGTCTGGTGACAAACGAAGGCAACGCACGCCTTGTCTCCACCCTGCCCCGCGTACATGTGGCTCTGGCAGGTCTGGAC
AAGCTGGTGCCCACCATGCACGATGCTCTGCGCACGCTCAAGGTGCTGCCCCGTAACGCCACGGGTCAGGCCATCACCTC
GTACGTCACATGGATCACAGGTGCCAACGAATGCGCCACCGGTCCTGACGGCAAAAAAGAAATGCACATCGTGTTTCTGG
ACAACGGCCGCCGCGCCATGGCCGACGACCCGCTGTACTCGCAGGTACTGCGCTGCGTGCGCTGCGGCGCCTGCGCCAAC
GTATGTCCCGTGTACCGTCTGGTCGGCGGACACAAAATGGGCCATATCTACATCGGCGCCATCGGTCTTATTCTCACCTA
CTTCTTCCACGGCTCCGACAAGGCAAAGAACCTGGTGCACAACTGCATCAACTGTGAAGCCTGCAAAAACATCTGCGCCG
GCGGCATCGACCTGCCCCGTCTGATCAAGGACATCCGCGCACGCCTGAACGAAGAAGGCGACATGCCCATCGAAACCACC
CTGCTGGGCAAGGTGCTGAAAAACCGCAAGCTCTTCCACACCCTGCTGCGCTTCGGCAAGTGGGCTCAGAAGCCGGTGCA
GGACGGTCCCTTCCTGCGCCACCTGCCCCTCATGTTCATGAAGGATCAGGGCTTCCGCCGGTTCCCCTCCGTGGCCGAAA
AGGCATTCCGCGACGAGTTTGAATCCATCAAGCCCAAAGTGGCCAACGCCAAGCTGCGCGTGGCGCTGTTTGCAGGCTGC
GTGCAGGACTTTGTCTACCCCGAGCAGATGAAAGCCGCCGTTAAGCTTTTCGCCGCACACGGAGTGGATGTGGACTTCCC
CATGGATCAGAGCTGCTGCGGTCTGCCGGTGCAGATGATGGGTGAGCGTCAGGCAACCATTGACGTGGCCGCACAGAACG
TCATGGCGTTCGATCCTGCCAAGTATGACTACATCGTCACGCTGTGCGCTTCCTGCGGCTCCCAACTCAAGGAATCGTAC
CCCAACATTCTGGCAGACAAGCCCGAGCTGGCCATCCGCACCAAGCAGTTCTCCGAGCGCGTCATCGACTTCAGCTCCTT
TGCGCATGACGTACTGGGCGTAAAGGCCGAAGAGTTCAACAAGTCGGACGAAAAAGTGGCCTACCACGCTTCGTGCCACC
TGTGCCGCGGCCTGCATGTCACCGAACAGCCCCGCAACCTCATCAACATGGCCGCCGAATACGCCAAGGCGGAAGAAGAA
GAGGTCTGCTGCGGTTTCGGCGGCACCTTCTCGGTCAAGTTCCCCGAACTTTCCGAAAAGCTGCTGGACAAAAAGCTGAC
CAACATTGAAGCCACCGGCGCCAAAAAAATGGTCGCCGACTGCCCCGGCTGCATCATGCAGCTGCGCGGCGGCTGCAAAT
CGTCCGGCCGCGACATTGAAGTGCGCCACGTAGCCGAGCTGCTTGCAGACAAGCTTAAATAG

Upstream 100 bases:

>100_bases
CATCAGCGGTCCCAGCCGTACCGCAGACATCGAACGCACCCTTGCACTGGGCGCCCACGGTCCCCTTGAACTGCACGTAT
TGCTGCTGGAGGATTAATCA

Downstream 100 bases:

>100_bases
TCGCGTCACTGCCAAACATACAAAGGCCACTACAGTGTAGTGGCCTTTTTTGTTATTTTCCGGCCTATTATTTTATTTAC
ACTGGAAATCACTGCAGATA

Product: iron-sulfur cluster-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MQNAKNLKEYRAELRESLDNDFLRSTMDKFAVAYPVGRANAFKGMDVQSLIAEVADAKDAAAKQMDQLYAQFKAEAEKRG
VKVHLAKTAQEANEIIAQIARDAGVKKIVKSKSMTSEETQFNHQVENEFEVVETDLGEWIIQLRHEGPTHMVMPAIHLSR
NQVADLFSDVTKQKQDNDPQKLTKVARRELRKEYATAEMGVTGANFCVASTGTIGLVTNEGNARLVSTLPRVHVALAGLD
KLVPTMHDALRTLKVLPRNATGQAITSYVTWITGANECATGPDGKKEMHIVFLDNGRRAMADDPLYSQVLRCVRCGACAN
VCPVYRLVGGHKMGHIYIGAIGLILTYFFHGSDKAKNLVHNCINCEACKNICAGGIDLPRLIKDIRARLNEEGDMPIETT
LLGKVLKNRKLFHTLLRFGKWAQKPVQDGPFLRHLPLMFMKDQGFRRFPSVAEKAFRDEFESIKPKVANAKLRVALFAGC
VQDFVYPEQMKAAVKLFAAHGVDVDFPMDQSCCGLPVQMMGERQATIDVAAQNVMAFDPAKYDYIVTLCASCGSQLKESY
PNILADKPELAIRTKQFSERVIDFSSFAHDVLGVKAEEFNKSDEKVAYHASCHLCRGLHVTEQPRNLINMAAEYAKAEEE
EVCCGFGGTFSVKFPELSEKLLDKKLTNIEATGAKKMVADCPGCIMQLRGGCKSSGRDIEVRHVAELLADKLK

Sequences:

>Translated_713_residues
MQNAKNLKEYRAELRESLDNDFLRSTMDKFAVAYPVGRANAFKGMDVQSLIAEVADAKDAAAKQMDQLYAQFKAEAEKRG
VKVHLAKTAQEANEIIAQIARDAGVKKIVKSKSMTSEETQFNHQVENEFEVVETDLGEWIIQLRHEGPTHMVMPAIHLSR
NQVADLFSDVTKQKQDNDPQKLTKVARRELRKEYATAEMGVTGANFCVASTGTIGLVTNEGNARLVSTLPRVHVALAGLD
KLVPTMHDALRTLKVLPRNATGQAITSYVTWITGANECATGPDGKKEMHIVFLDNGRRAMADDPLYSQVLRCVRCGACAN
VCPVYRLVGGHKMGHIYIGAIGLILTYFFHGSDKAKNLVHNCINCEACKNICAGGIDLPRLIKDIRARLNEEGDMPIETT
LLGKVLKNRKLFHTLLRFGKWAQKPVQDGPFLRHLPLMFMKDQGFRRFPSVAEKAFRDEFESIKPKVANAKLRVALFAGC
VQDFVYPEQMKAAVKLFAAHGVDVDFPMDQSCCGLPVQMMGERQATIDVAAQNVMAFDPAKYDYIVTLCASCGSQLKESY
PNILADKPELAIRTKQFSERVIDFSSFAHDVLGVKAEEFNKSDEKVAYHASCHLCRGLHVTEQPRNLINMAAEYAKAEEE
EVCCGFGGTFSVKFPELSEKLLDKKLTNIEATGAKKMVADCPGCIMQLRGGCKSSGRDIEVRHVAELLADKLK
>Mature_713_residues
MQNAKNLKEYRAELRESLDNDFLRSTMDKFAVAYPVGRANAFKGMDVQSLIAEVADAKDAAAKQMDQLYAQFKAEAEKRG
VKVHLAKTAQEANEIIAQIARDAGVKKIVKSKSMTSEETQFNHQVENEFEVVETDLGEWIIQLRHEGPTHMVMPAIHLSR
NQVADLFSDVTKQKQDNDPQKLTKVARRELRKEYATAEMGVTGANFCVASTGTIGLVTNEGNARLVSTLPRVHVALAGLD
KLVPTMHDALRTLKVLPRNATGQAITSYVTWITGANECATGPDGKKEMHIVFLDNGRRAMADDPLYSQVLRCVRCGACAN
VCPVYRLVGGHKMGHIYIGAIGLILTYFFHGSDKAKNLVHNCINCEACKNICAGGIDLPRLIKDIRARLNEEGDMPIETT
LLGKVLKNRKLFHTLLRFGKWAQKPVQDGPFLRHLPLMFMKDQGFRRFPSVAEKAFRDEFESIKPKVANAKLRVALFAGC
VQDFVYPEQMKAAVKLFAAHGVDVDFPMDQSCCGLPVQMMGERQATIDVAAQNVMAFDPAKYDYIVTLCASCGSQLKESY
PNILADKPELAIRTKQFSERVIDFSSFAHDVLGVKAEEFNKSDEKVAYHASCHLCRGLHVTEQPRNLINMAAEYAKAEEE
EVCCGFGGTFSVKFPELSEKLLDKKLTNIEATGAKKMVADCPGCIMQLRGGCKSSGRDIEVRHVAELLADKLK

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=397, Percent_Identity=35.7682619647355, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI1786497, Length=242, Percent_Identity=30.9917355371901, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI48994913, Length=438, Percent_Identity=24.2009132420091, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788576, Length=423, Percent_Identity=25.7683215130024, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 79071; Mature: 79071

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNAKNLKEYRAELRESLDNDFLRSTMDKFAVAYPVGRANAFKGMDVQSLIAEVADAKDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
AAKQMDQLYAQFKAEAEKRGVKVHLAKTAQEANEIIAQIARDAGVKKIVKSKSMTSEETQ
HHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FNHQVENEFEVVETDLGEWIIQLRHEGPTHMVMPAIHLSRNQVADLFSDVTKQKQDNDPQ
HHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHH
KLTKVARRELRKEYATAEMGVTGANFCVASTGTIGLVTNEGNARLVSTLPRVHVALAGLD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KLVPTMHDALRTLKVLPRNATGQAITSYVTWITGANECATGPDGKKEMHIVFLDNGRRAM
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCC
ADDPLYSQVLRCVRCGACANVCPVYRLVGGHKMGHIYIGAIGLILTYFFHGSDKAKNLVH
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
NCINCEACKNICAGGIDLPRLIKDIRARLNEEGDMPIETTLLGKVLKNRKLFHTLLRFGK
HHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WAQKPVQDGPFLRHLPLMFMKDQGFRRFPSVAEKAFRDEFESIKPKVANAKLRVALFAGC
HHCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VQDFVYPEQMKAAVKLFAAHGVDVDFPMDQSCCGLPVQMMGERQATIDVAAQNVMAFDPA
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHEECCC
KYDYIVTLCASCGSQLKESYPNILADKPELAIRTKQFSERVIDFSSFAHDVLGVKAEEFN
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
KSDEKVAYHASCHLCRGLHVTEQPRNLINMAAEYAKAEEEEVCCGFGGTFSVKFPELSEK
CCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHH
LLDKKLTNIEATGAKKMVADCPGCIMQLRGGCKSSGRDIEVRHVAELLADKLK
HHHHHHHCCCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQNAKNLKEYRAELRESLDNDFLRSTMDKFAVAYPVGRANAFKGMDVQSLIAEVADAKDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
AAKQMDQLYAQFKAEAEKRGVKVHLAKTAQEANEIIAQIARDAGVKKIVKSKSMTSEETQ
HHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FNHQVENEFEVVETDLGEWIIQLRHEGPTHMVMPAIHLSRNQVADLFSDVTKQKQDNDPQ
HHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHH
KLTKVARRELRKEYATAEMGVTGANFCVASTGTIGLVTNEGNARLVSTLPRVHVALAGLD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KLVPTMHDALRTLKVLPRNATGQAITSYVTWITGANECATGPDGKKEMHIVFLDNGRRAM
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCC
ADDPLYSQVLRCVRCGACANVCPVYRLVGGHKMGHIYIGAIGLILTYFFHGSDKAKNLVH
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
NCINCEACKNICAGGIDLPRLIKDIRARLNEEGDMPIETTLLGKVLKNRKLFHTLLRFGK
HHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WAQKPVQDGPFLRHLPLMFMKDQGFRRFPSVAEKAFRDEFESIKPKVANAKLRVALFAGC
HHCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VQDFVYPEQMKAAVKLFAAHGVDVDFPMDQSCCGLPVQMMGERQATIDVAAQNVMAFDPA
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHEECCC
KYDYIVTLCASCGSQLKESYPNILADKPELAIRTKQFSERVIDFSSFAHDVLGVKAEEFN
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
KSDEKVAYHASCHLCRGLHVTEQPRNLINMAAEYAKAEEEEVCCGFGGTFSVKFPELSEK
CCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHH
LLDKKLTNIEATGAKKMVADCPGCIMQLRGGCKSSGRDIEVRHVAELLADKLK
HHHHHHHCCCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA