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The map label for this gene is nrnA [H]

Identifier: 78358204

GI number: 78358204

Start: 3151964

End: 3152971

Strand: Direct

Name: nrnA [H]

Synonym: Dde_3164

Alternate gene names: 78358204

Gene position: 3151964-3152971 (Clockwise)

Preceding gene: 78358203

Following gene: 78358205

Centisome position: 84.5

GC content: 62.1

Gene sequence:

>1008_bases
ATGCGGGAAAGCACAAACCACGGCATGCCCGCGGCACGCATTGCCGAAATACTGCGCCGCGAAGACGACTTTCTCATTGC
CAGTCATTATAATCCGGACGGAGACGCCATAGGTTCCATGGCCGCTCTTGCGCACATGCTGCGCCGCATGGGCAAACAGG
TCATGCTGTACAACGAGTCCGGCGTGCCGGACCAGTTCGGCTGGCTGGATATGGGCGCCCCCTGCGTCACCGCGCTGGAC
GAGATAGACAGCTTTGCTCCGCGCCGGCTTGTGGTGCTCGACTGCGGCGATGACCGCCGCCCGGGCCAGGAAATCCGTTC
ACTGCTTTCTTCTGTTCCCAGCATCAACATTGATCATCACTTGGGCAATCCCCAGTTCGCCGATGTGAACTGGGTTGATT
CTTCCTGCGCCGCCACCGGCGAGATGGTCGCGCTTATCGGCCGTGAACTGGGCGCAGTGCCCGACGGCCCCGTGGGCGAA
GCTCTCTACCTTGCGCTGGTATCCGATACCGGTTCGTTCAGCTATGGCAACACCACGGCGCAGGTGCTTGAAATTGCAGC
CGACATCCTGCGCTGCGGGCTTGATCTCGGCGATTTCGGCCCGAAAATGCAGAACAACTGGAGCCTGAACCGCATGCAGC
TGTGGGGCAGACTGATGGGTGCCGTGCGCCTGAGTGCAGACGGACGCATTGCGGCGCTGGGCATCAGCTCCGCCGTGCTG
GAAGAAACCGGCACCACCATCGCCGATGCCGAAGGAATTATAAATTACATGCGCCGCATCCGTGGTGTACAGGTGGCCGT
CACCGTGCGCGAACACGGTCCCGGACGTTCCAAAGCCAGCCTGCGTTCCAACGGCACGGCCGATGTACAGCGGGTTGCCG
CCGGCTTCGGCGGAGGCGGGCACCGCAATGCCGCCGGTGCCGAACTGGACATGCCGCTGGAATCCGCCGTGCAGGAAATA
CTTTCATCCGTCTCGCGCAATCTTGCACTGGACGCCGAGGGCGCTTAA

Upstream 100 bases:

>100_bases
TACCAAGTGCCTGAGCATGATGGAAGCAGCCTGCCCCGAAGAAATGACCTACAGCGATATGGAATTTTTCGGCGCCGAGT
AGCGCCAAAGGAACACCGCC

Downstream 100 bases:

>100_bases
CTGTATGGCTGATTCGAAACTTGCACAGCAGCACGGGGTACTGGTACTTAACAAACCTAAAGGCCCCACATCGGCTCACT
GCATCGCCAGAATCAAACGG

Product: DHH family protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRESTNHGMPAARIAEILRREDDFLIASHYNPDGDAIGSMAALAHMLRRMGKQVMLYNESGVPDQFGWLDMGAPCVTALD
EIDSFAPRRLVVLDCGDDRRPGQEIRSLLSSVPSINIDHHLGNPQFADVNWVDSSCAATGEMVALIGRELGAVPDGPVGE
ALYLALVSDTGSFSYGNTTAQVLEIAADILRCGLDLGDFGPKMQNNWSLNRMQLWGRLMGAVRLSADGRIAALGISSAVL
EETGTTIADAEGIINYMRRIRGVQVAVTVREHGPGRSKASLRSNGTADVQRVAAGFGGGGHRNAAGAELDMPLESAVQEI
LSSVSRNLALDAEGA

Sequences:

>Translated_335_residues
MRESTNHGMPAARIAEILRREDDFLIASHYNPDGDAIGSMAALAHMLRRMGKQVMLYNESGVPDQFGWLDMGAPCVTALD
EIDSFAPRRLVVLDCGDDRRPGQEIRSLLSSVPSINIDHHLGNPQFADVNWVDSSCAATGEMVALIGRELGAVPDGPVGE
ALYLALVSDTGSFSYGNTTAQVLEIAADILRCGLDLGDFGPKMQNNWSLNRMQLWGRLMGAVRLSADGRIAALGISSAVL
EETGTTIADAEGIINYMRRIRGVQVAVTVREHGPGRSKASLRSNGTADVQRVAAGFGGGGHRNAAGAELDMPLESAVQEI
LSSVSRNLALDAEGA
>Mature_335_residues
MRESTNHGMPAARIAEILRREDDFLIASHYNPDGDAIGSMAALAHMLRRMGKQVMLYNESGVPDQFGWLDMGAPCVTALD
EIDSFAPRRLVVLDCGDDRRPGQEIRSLLSSVPSINIDHHLGNPQFADVNWVDSSCAATGEMVALIGRELGAVPDGPVGE
ALYLALVSDTGSFSYGNTTAQVLEIAADILRCGLDLGDFGPKMQNNWSLNRMQLWGRLMGAVRLSADGRIAALGISSAVL
EETGTTIADAEGIINYMRRIRGVQVAVTVREHGPGRSKASLRSNGTADVQRVAAGFGGGGHRNAAGAELDMPLESAVQEI
LSSVSRNLALDAEGA

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 35655; Mature: 35655

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRESTNHGMPAARIAEILRREDDFLIASHYNPDGDAIGSMAALAHMLRRMGKQVMLYNES
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCC
GVPDQFGWLDMGAPCVTALDEIDSFAPRRLVVLDCGDDRRPGQEIRSLLSSVPSINIDHH
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCC
LGNPQFADVNWVDSSCAATGEMVALIGRELGAVPDGPVGEALYLALVSDTGSFSYGNTTA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCHHH
QVLEIAADILRCGLDLGDFGPKMQNNWSLNRMQLWGRLMGAVRLSADGRIAALGISSAVL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCEEEEEHHHHHH
EETGTTIADAEGIINYMRRIRGVQVAVTVREHGPGRSKASLRSNGTADVQRVAAGFGGGG
HHCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHCCCCC
HRNAAGAELDMPLESAVQEILSSVSRNLALDAEGA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRESTNHGMPAARIAEILRREDDFLIASHYNPDGDAIGSMAALAHMLRRMGKQVMLYNES
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCC
GVPDQFGWLDMGAPCVTALDEIDSFAPRRLVVLDCGDDRRPGQEIRSLLSSVPSINIDHH
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCC
LGNPQFADVNWVDSSCAATGEMVALIGRELGAVPDGPVGEALYLALVSDTGSFSYGNTTA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCHHH
QVLEIAADILRCGLDLGDFGPKMQNNWSLNRMQLWGRLMGAVRLSADGRIAALGISSAVL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCEEEEEHHHHHH
EETGTTIADAEGIINYMRRIRGVQVAVTVREHGPGRSKASLRSNGTADVQRVAAGFGGGG
HHCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHCCCCC
HRNAAGAELDMPLESAVQEILSSVSRNLALDAEGA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]