| Definition | Desulfovibrio desulfuricans subsp. desulfuricans str. G20 chromosome, complete genome. |
|---|---|
| Accession | NC_007519 |
| Length | 3,730,232 |
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The map label for this gene is mrcA [H]
Identifier: 78358164
GI number: 78358164
Start: 3114943
End: 3117366
Strand: Direct
Name: mrcA [H]
Synonym: Dde_3124
Alternate gene names: 78358164
Gene position: 3114943-3117366 (Clockwise)
Preceding gene: 78358163
Following gene: 78358165
Centisome position: 83.51
GC content: 59.32
Gene sequence:
>2424_bases ATGAAACGTTTTCTCACATACTTTCTTGTCAGCGTCACAGGTCTTGCCCTGCTGGGCATGCTCGGGCTGGGCGGCATCTA TATATGGGCCACCAAAGACCTGCCCGGCTTTACCCGTATCACCGATTACCGCCCGCCGCTGGTCACCACGGTGTACGCGC GCGATAACAGCATTCTGGGGTATTTCTACCGCGAAAAACGCTTTCTGGCGCGCCTTGATGAAATGCCGCAGCATCTGCCT CTGGCCTTTCTCGCCGCAGAGGACGACTCCTTTTACCGGCATGAAGGCATAGACTTCCGCGCCATTCTGCGCGCCTTCAT GAAAAACATGCAGGCAGGCACCATCCGGCAGGGCGGTTCCACCATCACACAGCAGGTCATCAAACGCCTGTTGCTTACTT CCGAACGCAGCTACGAGCGCAAGATAAAAGAAGCCATTCTGGCCTACCGGCTGGAACGCTATCTGAGCAAAGATGAAATT CTGACCATATACCTGAACCAGATATATCTCGGCGCGGGGGCATATGGCGTGGAAGCCGCCGCGCGCAGCTACTTCGGCAA ACATGTGGGCGAACTGTCCATAGCCGAATCTGCGCTGCTGGCCGGTCTGCCGCAGGCTCCTTCCAAATACAACCCGCTCA ACAACCCGCAGGACGCATACACCCGTCAGCTGTATGTGCTGCACCGCATGCTTCAGCTCGGGTGGATAACACCCTCGCAA TACGACGCGGCCATCAATGAAAAGCTTGTGTTCACCTCCATGGCCGATCCTTCGTGGGGCACCGGCGCATGGTATCTGGA AGAAGTGCGCCGCAGGCTCATCGACTATCTGAGCGAAGACAACATGGAAAAACTGGGCATCAAGCTGGAACGCTACGGCG AGGACGCCGTGTATGAATCCGGCCTGCATGTTTACACCGCCATGGACCCCAAGCACCAGAAGTACGCCGAACAGTCACTG CGCGACGGGCTGGTGGCCTCTACAAAACGGCGGGGCTGGCGCGGCCCTGTGGAGCATCTGGAAAGCAAGGAAGCACGCGA AGCTTTTCTGCGTGACAACCCCGTGGATGCGGCGGCAATGCAGCACGAAGGCTGGATAAAAGTGCTGGTCACCCGCGTGA CGGCCGCAGGGGCCGATGTGCGCTTTGGCAGCTACAAGGGCCGGATGGACGTGGAAACCATGCACTGGTGCCGTACGCCC GACCCCACCGTGGTGACGGACTATGTGCCCGCCGTGAAAGATGCCCGTACGGTGGTCAAAGCGGGCGATGTGGTATGGGC GCAGCTTATGCTGCCCGATGCGGGCAAAAGCTTTGATGCCGCCTCCGTCACGCCTGATACGGACTTTTCACTGGCCATCG CGCAGTACCCCGAAGTGCAGGGGGCACTGGTTTCCATAGAACCGCAGACGGGCGATGTGGTGGCACTGGTCGGCGGCTAT TCCTTTGCCGACAGCCAGTACAACCGCGCCGTGCAGGCCAAACGCCAGCCCGGTTCCGCTTTCAAGCCCATTGTCTATTC CACCGCGCTGGACAACGGCTACACACCGGCATCCACGGTACTGGACGCCCCGTTTGTCTATACCGACGACGCCACGGCCA AAACATGGCGCCCCGAAAACTTTTCGGGAGAATTCTACGGCCCCACGCTGCTGCGCACCGCGCTGGTCAAATCGCGTAAC CTGTGTACCATCCGCATTGCACAGGACATCGGCATACCGGCCATTGTCGAACGGGCCAAAGCACTGGGACTTGAAGGGCC CTTCCCCTTCGACCTTTCGGTAAGTCTGGGGTCTGTGGCCGTTTCGCCTCTGAACCTTACAGAAGCATACACGGCGTTCG CCCATGAAGGTCTGCGCGCACAACACCGCATGATCACCGGCATCAAATCGGCATGGGACGAACCCATAGCCACCTTTGAG CCGCAGCAGACAGAAGCGCTGACACCGCAGAACGCCTATATCATGGCGTCGCTGATGAAAGAGGTAGTGCGCGACGGCAC CGGCTTCCGCGCACGGGTGCTCAAACGTCCTCTGGGCGGCAAAACCGGCACATCCAACGACGAGCGTGACGCATGGTTTG TTCTCATCTCTCCGTACCTTGTCTCGGTGTCCTATGTGGGCTTTGACGACCTGACCCCCATGGGCAAATGGGAAACCGGC TCGCGGGCGGCATCGCCCATTGTGGTCGGCTACCGTCAGGGTGTGGAAGAAGACTACCCCGTACAGGATTTTCCCATGCC TCCCGGCATCGTGCAGGTGCGCATTGACGGCAAAACAGGAAATCTTGCGGGACCCGGCTCTGAAACAAGTTACTTCATGC CTTTCAAGGAAGGAACCCAGCCCACCGTGGTGGAAGGTTCCGCCCCCCGCCACGGCGCCGACGACGCCCGCAGCGGCGAA GACCTTATGAAGCAGATGTTCTGA
Upstream 100 bases:
>100_bases CTGATGTTCGGCCGCCTGCGACTTGCGTGGGGGCTTGATCCGGAGCATGACGAAGACGGCAACCGCTATCCGCTTTGCGA CCATACCCGATAAAAATATC
Downstream 100 bases:
>100_bases TCTGCCGGCACCGGCAACGCCCCGCGGAATTTCCCGCGGGGCGTTTTTCATGGCGGCAGTTCTGGCTCAGCCGGTCAGGC TGTGGTACACCGGTCATGAC
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 807; Mature: 807
Protein sequence:
>807_residues MKRFLTYFLVSVTGLALLGMLGLGGIYIWATKDLPGFTRITDYRPPLVTTVYARDNSILGYFYREKRFLARLDEMPQHLP LAFLAAEDDSFYRHEGIDFRAILRAFMKNMQAGTIRQGGSTITQQVIKRLLLTSERSYERKIKEAILAYRLERYLSKDEI LTIYLNQIYLGAGAYGVEAAARSYFGKHVGELSIAESALLAGLPQAPSKYNPLNNPQDAYTRQLYVLHRMLQLGWITPSQ YDAAINEKLVFTSMADPSWGTGAWYLEEVRRRLIDYLSEDNMEKLGIKLERYGEDAVYESGLHVYTAMDPKHQKYAEQSL RDGLVASTKRRGWRGPVEHLESKEAREAFLRDNPVDAAAMQHEGWIKVLVTRVTAAGADVRFGSYKGRMDVETMHWCRTP DPTVVTDYVPAVKDARTVVKAGDVVWAQLMLPDAGKSFDAASVTPDTDFSLAIAQYPEVQGALVSIEPQTGDVVALVGGY SFADSQYNRAVQAKRQPGSAFKPIVYSTALDNGYTPASTVLDAPFVYTDDATAKTWRPENFSGEFYGPTLLRTALVKSRN LCTIRIAQDIGIPAIVERAKALGLEGPFPFDLSVSLGSVAVSPLNLTEAYTAFAHEGLRAQHRMITGIKSAWDEPIATFE PQQTEALTPQNAYIMASLMKEVVRDGTGFRARVLKRPLGGKTGTSNDERDAWFVLISPYLVSVSYVGFDDLTPMGKWETG SRAASPIVVGYRQGVEEDYPVQDFPMPPGIVQVRIDGKTGNLAGPGSETSYFMPFKEGTQPTVVEGSAPRHGADDARSGE DLMKQMF
Sequences:
>Translated_807_residues MKRFLTYFLVSVTGLALLGMLGLGGIYIWATKDLPGFTRITDYRPPLVTTVYARDNSILGYFYREKRFLARLDEMPQHLP LAFLAAEDDSFYRHEGIDFRAILRAFMKNMQAGTIRQGGSTITQQVIKRLLLTSERSYERKIKEAILAYRLERYLSKDEI LTIYLNQIYLGAGAYGVEAAARSYFGKHVGELSIAESALLAGLPQAPSKYNPLNNPQDAYTRQLYVLHRMLQLGWITPSQ YDAAINEKLVFTSMADPSWGTGAWYLEEVRRRLIDYLSEDNMEKLGIKLERYGEDAVYESGLHVYTAMDPKHQKYAEQSL RDGLVASTKRRGWRGPVEHLESKEAREAFLRDNPVDAAAMQHEGWIKVLVTRVTAAGADVRFGSYKGRMDVETMHWCRTP DPTVVTDYVPAVKDARTVVKAGDVVWAQLMLPDAGKSFDAASVTPDTDFSLAIAQYPEVQGALVSIEPQTGDVVALVGGY SFADSQYNRAVQAKRQPGSAFKPIVYSTALDNGYTPASTVLDAPFVYTDDATAKTWRPENFSGEFYGPTLLRTALVKSRN LCTIRIAQDIGIPAIVERAKALGLEGPFPFDLSVSLGSVAVSPLNLTEAYTAFAHEGLRAQHRMITGIKSAWDEPIATFE PQQTEALTPQNAYIMASLMKEVVRDGTGFRARVLKRPLGGKTGTSNDERDAWFVLISPYLVSVSYVGFDDLTPMGKWETG SRAASPIVVGYRQGVEEDYPVQDFPMPPGIVQVRIDGKTGNLAGPGSETSYFMPFKEGTQPTVVEGSAPRHGADDARSGE DLMKQMF >Mature_807_residues MKRFLTYFLVSVTGLALLGMLGLGGIYIWATKDLPGFTRITDYRPPLVTTVYARDNSILGYFYREKRFLARLDEMPQHLP LAFLAAEDDSFYRHEGIDFRAILRAFMKNMQAGTIRQGGSTITQQVIKRLLLTSERSYERKIKEAILAYRLERYLSKDEI LTIYLNQIYLGAGAYGVEAAARSYFGKHVGELSIAESALLAGLPQAPSKYNPLNNPQDAYTRQLYVLHRMLQLGWITPSQ YDAAINEKLVFTSMADPSWGTGAWYLEEVRRRLIDYLSEDNMEKLGIKLERYGEDAVYESGLHVYTAMDPKHQKYAEQSL RDGLVASTKRRGWRGPVEHLESKEAREAFLRDNPVDAAAMQHEGWIKVLVTRVTAAGADVRFGSYKGRMDVETMHWCRTP DPTVVTDYVPAVKDARTVVKAGDVVWAQLMLPDAGKSFDAASVTPDTDFSLAIAQYPEVQGALVSIEPQTGDVVALVGGY SFADSQYNRAVQAKRQPGSAFKPIVYSTALDNGYTPASTVLDAPFVYTDDATAKTWRPENFSGEFYGPTLLRTALVKSRN LCTIRIAQDIGIPAIVERAKALGLEGPFPFDLSVSLGSVAVSPLNLTEAYTAFAHEGLRAQHRMITGIKSAWDEPIATFE PQQTEALTPQNAYIMASLMKEVVRDGTGFRARVLKRPLGGKTGTSNDERDAWFVLISPYLVSVSYVGFDDLTPMGKWETG SRAASPIVVGYRQGVEEDYPVQDFPMPPGIVQVRIDGKTGNLAGPGSETSYFMPFKEGTQPTVVEGSAPRHGADDARSGE DLMKQMF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=642, Percent_Identity=34.1121495327103, Blast_Score=332, Evalue=7e-92, Organism=Escherichia coli, GI1786343, Length=305, Percent_Identity=33.4426229508197, Blast_Score=130, Evalue=3e-31, Organism=Escherichia coli, GI1788867, Length=158, Percent_Identity=39.873417721519, Blast_Score=107, Evalue=4e-24, Organism=Escherichia coli, GI1789601, Length=163, Percent_Identity=39.2638036809816, Blast_Score=106, Evalue=5e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 89586; Mature: 89586
Theoretical pI: Translated: 6.41; Mature: 6.41
Prosite motif: PS00024 HEMOPEXIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRFLTYFLVSVTGLALLGMLGLGGIYIWATKDLPGFTRITDYRPPLVTTVYARDNSILG CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEE YFYREKRFLARLDEMPQHLPLAFLAAEDDSFYRHEGIDFRAILRAFMKNMQAGTIRQGGS HHHHHHHHHHHHHHCHHHCCEEEEEECCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCH TITQQVIKRLLLTSERSYERKIKEAILAYRLERYLSKDEILTIYLNQIYLGAGAYGVEAA HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHH ARSYFGKHVGELSIAESALLAGLPQAPSKYNPLNNPQDAYTRQLYVLHRMLQLGWITPSQ HHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH YDAAINEKLVFTSMADPSWGTGAWYLEEVRRRLIDYLSEDNMEKLGIKLERYGEDAVYES HHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHCCCHHHHHC GLHVYTAMDPKHQKYAEQSLRDGLVASTKRRGWRGPVEHLESKEAREAFLRDNPVDAAAM CCEEEEECCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH QHEGWIKVLVTRVTAAGADVRFGSYKGRMDVETMHWCRTPDPTVVTDYVPAVKDARTVVK CCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCCCEEECCHHHHHHHHHHHH AGDVVWAQLMLPDAGKSFDAASVTPDTDFSLAIAQYPEVQGALVSIEPQTGDVVALVGGY CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEECCC SFADSQYNRAVQAKRQPGSAFKPIVYSTALDNGYTPASTVLDAPFVYTDDATAKTWRPEN CCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHCCCEEEECCCCCCCCCCCC FSGEFYGPTLLRTALVKSRNLCTIRIAQDIGIPAIVERAKALGLEGPFPFDLSVSLGSVA CCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCEE VSPLNLTEAYTAFAHEGLRAQHRMITGIKSAWDEPIATFEPQQTEALTPQNAYIMASLMK ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH EVVRDGTGFRARVLKRPLGGKTGTSNDERDAWFVLISPYLVSVSYVGFDDLTPMGKWETG HHHHCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHEEEECCCCCCCCCCCCCCC SRAASPIVVGYRQGVEEDYPVQDFPMPPGIVQVRIDGKTGNLAGPGSETSYFMPFKEGTQ CCCCCCEEEEHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCC PTVVEGSAPRHGADDARSGEDLMKQMF CEEEECCCCCCCCCCCCCHHHHHHHCC >Mature Secondary Structure MKRFLTYFLVSVTGLALLGMLGLGGIYIWATKDLPGFTRITDYRPPLVTTVYARDNSILG CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEE YFYREKRFLARLDEMPQHLPLAFLAAEDDSFYRHEGIDFRAILRAFMKNMQAGTIRQGGS HHHHHHHHHHHHHHCHHHCCEEEEEECCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCH TITQQVIKRLLLTSERSYERKIKEAILAYRLERYLSKDEILTIYLNQIYLGAGAYGVEAA HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHH ARSYFGKHVGELSIAESALLAGLPQAPSKYNPLNNPQDAYTRQLYVLHRMLQLGWITPSQ HHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH YDAAINEKLVFTSMADPSWGTGAWYLEEVRRRLIDYLSEDNMEKLGIKLERYGEDAVYES HHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHCCCHHHHHC GLHVYTAMDPKHQKYAEQSLRDGLVASTKRRGWRGPVEHLESKEAREAFLRDNPVDAAAM CCEEEEECCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH QHEGWIKVLVTRVTAAGADVRFGSYKGRMDVETMHWCRTPDPTVVTDYVPAVKDARTVVK CCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCCCEEECCHHHHHHHHHHHH AGDVVWAQLMLPDAGKSFDAASVTPDTDFSLAIAQYPEVQGALVSIEPQTGDVVALVGGY CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEECCC SFADSQYNRAVQAKRQPGSAFKPIVYSTALDNGYTPASTVLDAPFVYTDDATAKTWRPEN CCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHCCCEEEECCCCCCCCCCCC FSGEFYGPTLLRTALVKSRNLCTIRIAQDIGIPAIVERAKALGLEGPFPFDLSVSLGSVA CCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCEE VSPLNLTEAYTAFAHEGLRAQHRMITGIKSAWDEPIATFEPQQTEALTPQNAYIMASLMK ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH EVVRDGTGFRARVLKRPLGGKTGTSNDERDAWFVLISPYLVSVSYVGFDDLTPMGKWETG HHHHCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHEEEECCCCCCCCCCCCCCC SRAASPIVVGYRQGVEEDYPVQDFPMPPGIVQVRIDGKTGNLAGPGSETSYFMPFKEGTQ CCCCCCEEEEHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCC PTVVEGSAPRHGADDARSGEDLMKQMF CEEEECCCCCCCCCCCCCHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10984043; 7901733 [H]