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The map label for this gene is ywdH [H]

Identifier: 78358161

GI number: 78358161

Start: 3111211

End: 3112593

Strand: Direct

Name: ywdH [H]

Synonym: Dde_3121

Alternate gene names: 78358161

Gene position: 3111211-3112593 (Clockwise)

Preceding gene: 78358157

Following gene: 78358162

Centisome position: 83.41

GC content: 62.55

Gene sequence:

>1383_bases
ATGACACCTGAACGCATATACGAAGTGACGGAAGCCCAGAGAGCTTTTTTCCAGTCCGGAGCCACCCTTGACGTGGACGG
ACGCATTGCATCGCTGCGCACCCTGCGCGGCGCCGTGCATGATTACACCCGTCGCTTTATTGTAGCTGCGGCACAGGATG
CCGGACTTTCCGAGCACATGGTGCTTGCGGCTGAAATAGCCCCCGTCATCAACGACATCGACCACATGATCAAACGTCTG
CCCGCGCTGGCAAAGGGACGGCTGGTGCGTCGTTCGCGGCTGCATATGTGGGGCTGGTCGCGCAGCGTGCCCCGCCCCGC
AGGCATTGCCGTGGCCGTAACCGCCGCGGATATGCCCGTACAGCGCGCCCTTATGCCGGTGGTATCTGCCCTTGCCGCGG
GCACCCCGCTGCTGCTGGCACTTTCTCCCCGCACTCCGGCTGTCAACGGCATTGTGGAGCGCCTTGTGCAGCAGTTTTTC
AAGCCGGAACAGATAACCGTGACCACTGCGGACAATGAAACCACAGAGGCCATTCTCGGACAGCGTTTCGATGCCTGCCT
GTGCTCCGCACCGCGCGAAACCGCCGTCCGGTTTGCCCGCGCCGCTGCGGAACACCTTGTGCCCGCCGTCATTGAAACAG
CCGAACACCGCAATCCGGCCATAGTGCTTGAAGATGCCGATATCCGGCTGGCAGCGCGGCGCATAGTATGGGCCAAAACT
CTTGCCGCCGGTCAGACCGCCGCCGCGCCGGACTATCTGGTGGTGCACGGCGCAGTCCGCGAACGCCTGCTGGCAGCCCT
GCGCAAAGAACTGGAAGCGCAGCACGGCGCCATACCCTCCGCAAGTTCCGCATTCGGCCGCATGACAGACAACGCAGCCT
ATGAAGAAGCTGCGGCGTTTCTGACTGACGGCACGCCGGTCATAGGCGGCGACACCGACCCCGCAGGCAGGTTCATCAAC
TTTACCGTACTGGAAAACGTACAGCCGGACGCACCGGTCATGCGTTCCGTCACCCGCAGTCCGGTGCTGCCGCTTTTTGA
GGTGCAGTCTGCGGAACAGGCCGTTGAACTGGTGAACAGCCGTCCCGCACCGCTGGCTCTGTATGTGTTCAGCACCGATG
TGTTTACCGCACGCAAAGTGCTGGATGCCACAACATCGGGCACAGCGGCGGTCAACGACGTGCTGGTGCAGACCGTGTAC
CCCGCCCTGCCCTTCGGCGATGCGGCAGGCGGCGGCATGGGCAGCCACCGCGGCGAGGCGGGATTTTTTGCCTTTTCCAG
ACTGCGCAGTGTCACACGCGGCACAAACTTCATCGACCTGCCGTTCCGGTTCAGCCCCGATGCCGGCTGGAAGCAGAAAA
TCCTGCGGTACATCATCAGATAA

Upstream 100 bases:

>100_bases
GCTCCTGTGCAAAAAAAGCGCAGTGCGGTCTAGCCAGCTCCAAGTATGCGTGTTATCTTGCACGGGTATCACTTTCACAC
GCACACCAAGGAGCCTGACC

Downstream 100 bases:

>100_bases
CAGCCGCGCCGCCTGCCGCAGACCGGCAGGCGGCGTCGTTGTTCCGCAAGGATTTTATCCGCCGCGTCGTCTCTGTGCAG
TACCGGACAGGCAGGCTCTG

Product: putative aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTPERIYEVTEAQRAFFQSGATLDVDGRIASLRTLRGAVHDYTRRFIVAAAQDAGLSEHMVLAAEIAPVINDIDHMIKRL
PALAKGRLVRRSRLHMWGWSRSVPRPAGIAVAVTAADMPVQRALMPVVSALAAGTPLLLALSPRTPAVNGIVERLVQQFF
KPEQITVTTADNETTEAILGQRFDACLCSAPRETAVRFARAAAEHLVPAVIETAEHRNPAIVLEDADIRLAARRIVWAKT
LAAGQTAAAPDYLVVHGAVRERLLAALRKELEAQHGAIPSASSAFGRMTDNAAYEEAAAFLTDGTPVIGGDTDPAGRFIN
FTVLENVQPDAPVMRSVTRSPVLPLFEVQSAEQAVELVNSRPAPLALYVFSTDVFTARKVLDATTSGTAAVNDVLVQTVY
PALPFGDAAGGGMGSHRGEAGFFAFSRLRSVTRGTNFIDLPFRFSPDAGWKQKILRYIIR

Sequences:

>Translated_460_residues
MTPERIYEVTEAQRAFFQSGATLDVDGRIASLRTLRGAVHDYTRRFIVAAAQDAGLSEHMVLAAEIAPVINDIDHMIKRL
PALAKGRLVRRSRLHMWGWSRSVPRPAGIAVAVTAADMPVQRALMPVVSALAAGTPLLLALSPRTPAVNGIVERLVQQFF
KPEQITVTTADNETTEAILGQRFDACLCSAPRETAVRFARAAAEHLVPAVIETAEHRNPAIVLEDADIRLAARRIVWAKT
LAAGQTAAAPDYLVVHGAVRERLLAALRKELEAQHGAIPSASSAFGRMTDNAAYEEAAAFLTDGTPVIGGDTDPAGRFIN
FTVLENVQPDAPVMRSVTRSPVLPLFEVQSAEQAVELVNSRPAPLALYVFSTDVFTARKVLDATTSGTAAVNDVLVQTVY
PALPFGDAAGGGMGSHRGEAGFFAFSRLRSVTRGTNFIDLPFRFSPDAGWKQKILRYIIR
>Mature_459_residues
TPERIYEVTEAQRAFFQSGATLDVDGRIASLRTLRGAVHDYTRRFIVAAAQDAGLSEHMVLAAEIAPVINDIDHMIKRLP
ALAKGRLVRRSRLHMWGWSRSVPRPAGIAVAVTAADMPVQRALMPVVSALAAGTPLLLALSPRTPAVNGIVERLVQQFFK
PEQITVTTADNETTEAILGQRFDACLCSAPRETAVRFARAAAEHLVPAVIETAEHRNPAIVLEDADIRLAARRIVWAKTL
AAGQTAAAPDYLVVHGAVRERLLAALRKELEAQHGAIPSASSAFGRMTDNAAYEEAAAFLTDGTPVIGGDTDPAGRFINF
TVLENVQPDAPVMRSVTRSPVLPLFEVQSAEQAVELVNSRPAPLALYVFSTDVFTARKVLDATTSGTAAVNDVLVQTVYP
ALPFGDAAGGGMGSHRGEAGFFAFSRLRSVTRGTNFIDLPFRFSPDAGWKQKILRYIIR

Specific function: Acts Almost Equally Well On Phenylacetaldehyde, 4- Hydroxyphenylacetaldehyde And 3,4-Dihydroxyphenylacetaldehyde. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557303, Length=454, Percent_Identity=28.4140969162996, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI73466520, Length=454, Percent_Identity=28.4140969162996, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI206597441, Length=427, Percent_Identity=29.7423887587822, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI206597439, Length=427, Percent_Identity=29.7423887587822, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI22907049, Length=427, Percent_Identity=29.7423887587822, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI4502043, Length=418, Percent_Identity=30.3827751196172, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI238814371, Length=418, Percent_Identity=30.3827751196172, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI71773324, Length=326, Percent_Identity=33.1288343558282, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI73695881, Length=355, Percent_Identity=28.4507042253521, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI73695879, Length=355, Percent_Identity=28.4507042253521, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI25777730, Length=337, Percent_Identity=24.6290801186944, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI115387104, Length=351, Percent_Identity=22.7920227920228, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI11095441, Length=355, Percent_Identity=23.3802816901408, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI153266822, Length=341, Percent_Identity=21.7008797653959, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI25777732, Length=339, Percent_Identity=21.5339233038348, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081896, Length=353, Percent_Identity=26.0623229461756, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081926, Length=388, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789015, Length=345, Percent_Identity=22.8985507246377, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787558, Length=338, Percent_Identity=21.8934911242604, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25146391, Length=426, Percent_Identity=31.6901408450704, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI32566756, Length=426, Percent_Identity=31.6901408450704, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI25146394, Length=426, Percent_Identity=31.6901408450704, Blast_Score=224, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17564084, Length=431, Percent_Identity=28.7703016241299, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17562198, Length=338, Percent_Identity=23.9644970414201, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25143874, Length=352, Percent_Identity=21.875, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25143876, Length=352, Percent_Identity=21.875, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32564736, Length=339, Percent_Identity=22.7138643067847, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25144435, Length=339, Percent_Identity=22.7138643067847, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534119, Length=355, Percent_Identity=22.5352112676056, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71986308, Length=355, Percent_Identity=22.2535211267606, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534176, Length=347, Percent_Identity=22.478386167147, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323757, Length=480, Percent_Identity=26.25, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=447, Percent_Identity=23.0425055928412, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319478, Length=355, Percent_Identity=24.2253521126761, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=374, Percent_Identity=20.0534759358289, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325196, Length=364, Percent_Identity=21.7032967032967, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281360301, Length=452, Percent_Identity=26.5486725663717, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI281360299, Length=452, Percent_Identity=26.5486725663717, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI281360297, Length=452, Percent_Identity=26.5486725663717, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI281360295, Length=452, Percent_Identity=26.5486725663717, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24586250, Length=452, Percent_Identity=26.5486725663717, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI45552499, Length=452, Percent_Identity=26.5486725663717, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI281360303, Length=452, Percent_Identity=26.5486725663717, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI281360293, Length=246, Percent_Identity=25.609756097561, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281362580, Length=351, Percent_Identity=21.6524216524217, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI62472918, Length=351, Percent_Identity=21.6524216524217, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI62472926, Length=351, Percent_Identity=21.6524216524217, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI62472936, Length=351, Percent_Identity=21.6524216524217, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356737, Length=351, Percent_Identity=21.6524216524217, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR012394 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.3 [H]

Molecular weight: Translated: 49661; Mature: 49530

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPERIYEVTEAQRAFFQSGATLDVDGRIASLRTLRGAVHDYTRRFIVAAAQDAGLSEHM
CCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHH
VLAAEIAPVINDIDHMIKRLPALAKGRLVRRSRLHMWGWSRSVPRPAGIAVAVTAADMPV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCH
QRALMPVVSALAAGTPLLLALSPRTPAVNGIVERLVQQFFKPEQITVTTADNETTEAILG
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
QRFDACLCSAPRETAVRFARAAAEHLVPAVIETAEHRNPAIVLEDADIRLAARRIVWAKT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
LAAGQTAAAPDYLVVHGAVRERLLAALRKELEAQHGAIPSASSAFGRMTDNAAYEEAAAF
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHH
LTDGTPVIGGDTDPAGRFINFTVLENVQPDAPVMRSVTRSPVLPLFEVQSAEQAVELVNS
HCCCCEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
RPAPLALYVFSTDVFTARKVLDATTSGTAAVNDVLVQTVYPALPFGDAAGGGMGSHRGEA
CCCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
GFFAFSRLRSVTRGTNFIDLPFRFSPDAGWKQKILRYIIR
HHHHHHHHHHHHCCCCEEECCEEECCCCCHHHHHHHHHHC
>Mature Secondary Structure 
TPERIYEVTEAQRAFFQSGATLDVDGRIASLRTLRGAVHDYTRRFIVAAAQDAGLSEHM
CHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHH
VLAAEIAPVINDIDHMIKRLPALAKGRLVRRSRLHMWGWSRSVPRPAGIAVAVTAADMPV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCH
QRALMPVVSALAAGTPLLLALSPRTPAVNGIVERLVQQFFKPEQITVTTADNETTEAILG
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
QRFDACLCSAPRETAVRFARAAAEHLVPAVIETAEHRNPAIVLEDADIRLAARRIVWAKT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
LAAGQTAAAPDYLVVHGAVRERLLAALRKELEAQHGAIPSASSAFGRMTDNAAYEEAAAF
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHH
LTDGTPVIGGDTDPAGRFINFTVLENVQPDAPVMRSVTRSPVLPLFEVQSAEQAVELVNS
HCCCCEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
RPAPLALYVFSTDVFTARKVLDATTSGTAAVNDVLVQTVYPALPFGDAAGGGMGSHRGEA
CCCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
GFFAFSRLRSVTRGTNFIDLPFRFSPDAGWKQKILRYIIR
HHHHHHHHHHHHCCCCEEECCEEECCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]